Murine peritoneal macrophages treated with cisplatin and interferon-γ undergo NO-mediated apoptosis via activation of an endonuclease

Anti-Cancer Drugs

Volumn 9, Issue 4, 1998, Pages 333-341

  Ranjan, Priya ^a   Sodhi, Ajit ^a   Singh, Sukh Mahendra ^a  

^a BANARAS HINDU UNIVERSITY   (India)

Author keywords

Apoptosis; Cisplatin; Endonuclease; Interferon ; Macrophage; Nitric oxide

Indexed keywords

AURINTRICARBOXYLIC ACID; CISPLATIN; DNA FRAGMENT; ENDONUCLEASE; ENZYME INHIBITOR; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE INHIBITOR; NITROPRUSSIDE SODIUM; RECOMBINANT GAMMA INTERFERON;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; FEMALE; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL;

EID: 0031777593     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-199804000-00007     Document Type: Article

References (39)

1. Keller R, Geiges M, Keist R. L-arginine-dependent reactive nitrogen intermediates as mediators of tumor cell killing by activated macrophages. Cancer Res 1990; 50: 1421-5.
2. Nathan CF, Brukner LH, Silverstein SC, Cohn ZA. Extracellular cytolysis by activated macrophages and granulocytes: I. Pharmacological triggering of effecter cells and release of hydrogen peroxide. J Exp Med 1979; 149: 84-9.
3. Adams DO, Nathan CF. Molecular mechanisms in tumor-cell killing by activated macrophages. Immunol Today 1983; 4: 166-77.
4. Klostergaard J, Leroux ME, Hung MC. Cellular models of macrophage tumoricidal effecter mechanisms in vitro: characterization of cytolytic responses to tumor necrosis factor and nitric oxide pathways in vitro. J Immunol 1991; 147: 2802-8.
5. Stuehr DH, Nathan CF. Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. J Exp Med 1989; 169: 1543-55.
6. Farias-Eisener R, Sherman MP, Aeberhard E, Choudhuri G. Nitric oxide is an important mediator for tumoricidal activity in vivo. Proc Natl Acad Sci USA 1994; 91: 9407-11.
7. Stamler JS. Redox signaling: nitrosylation and related target interactions of nitric oxide. Cell 1994; 78: 931-6.
8. Kim YM, Bergonia HA, Muller C, Pitt BR, Watkins WD, Lancaster JR. Loss and degradation of enzyme-bound heme induced by cellular nitric oxide synthesis. J Biol Chem 1995; 270: 5710-3.
9. Cui S, Reichner JS, Mateo RB, Albina JB. Activated murine peritoneal macrophages induce apoptosis in tumor cells through nitric oxide-dependent or -independent mechanisms. Cancer Res 1994; 54: 2462-7.
10. Ranjan P, Sodhi A, Srivastava A. Cisplatin and interferon-γ treated murine peritoneal macrophages induce apoptosis in tumor cells. Anti-Cancer Drugs 1997; 8: 797-806.
11. Sarih M, Souvannavong V, Adam A. Nitric oxide synthase induces macrophage death by apoptosis. Biochem Biophy Res Commun 1993; 191: 503-8.
12. Albina EJ, Cui S, Mateo RB, Reichner JS. Nitric oxide mediated apoptosis in murine peritoneal macrophages. J Immunol 1993; 150: 5080-5.
13. Wyllie AH, Kerr JFR, Currie AR. Cell death: the significance of apoptosis. Int Rev Cytol 1980; 8: 251-6.
14. Terenzi F, Guerra MJMD, Casado M, Hortelano S, Leoni S, Bosca L. Bacterial lipopeptides induce nitric oxide synthase and promote apoptosis through nitric oxide-independent pathways in rat macrophages. J Biol Chem 1995; 270: 6017-21.
15. Rosenberg B. Fundamental studies with cisplatin. Cancer 1984; 55: 2303-16.
16. Gately DP, Howell SB. Cellular accumulation of anticancer agent cisplatin: a review. Br J Cancer 1993; 67: 1771-6.
17. Sodhi A, Basu S. Role of human blood monocytes in up regulation of lymphokine (interleukin-2)-activated killer cell activity with cisplatin and FK-565: involvement of calcium ion. Immunol Lett 1992; 32: 139-46.
18. Kleinerman ES, Zwelling LA, Muchmore AV. Enhancement of naturally occurring human monocyte mediated cytotoxicity by cis-dichlorodiamine platinum(II). Cancer Res 1980; 40: 3099-102.
19. Sodhi A, Pai K, Singh RK, Singh SM. Activation of human NK cells and monocytes with cisplatin in vitro. Int J Immunopharmacol 1990; 12: 893-8.
20. Sodhi A, Gupta P, Singh SM. In vivo activation of murine peritoneal macrophages by intraperitoneal administration of cisplatin. Arch Immunol Ther Exp 1988; 36: 3003-14.
21. Sodhi A, Singh SM. Release of cytotoxic factor(s) by murine macrophages in vitro on treatment with cisplatin. Int J Immunopharmacol 1986; 8: 701-7.
22. Lichtenstein AK, Pende D. Enhancement of natural killer cytotoxicity by cis-dichlorodiamine platinum(II) in vivo and in vitro. Cancer Res 1986; 46: 639-44.
23. Singh SM, Sodhi A. Interaction between cisplatin treated macrophages and Dalton's lymphoma cells in vitro. Exp Cell Biol 1988; 56: 1-11.
24. - and interleukin-1. Nat Immun Cell Growth Regul 1989; 8: 108-16.
25. Eastman A. Activation of programmed cell death by anticancer agents: cisplatin as a model system. Cancer Cells 1990; 2: 275-80.
26. Sellins KS, Cohen JJ. Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes. J Immunol 1987; 139: 3199-206.
27. Prigent P, Blanpied C, Aten J, Hirsch F. A safe and rapid method for analyzing apoptosis induced fragmentation of DNA extracted from tissues or cultured cells. J Immunol Methods 1993; 160: 139-40.
28. Ueda N, Shah SV. Role of intracellular calcium in hydrogen peroxide-induced renal tubular cell injury. Am J Physiol 1992; 263: F214-21.
29. Ding AH, Nathan CF, Stuehr DJ. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages: comparison of activating cytokines and evidence for independent production. J Immunol 1988; 141: 2407-67.
30. Mogil RJ, Shi Y, Bissonnette, Bromley P, Yamaguchi I, Green DR. Role of DNA fragmentation in T cell activation induced apoptosis in vitro and in vivo. J Immunol 1994; 152: 1674-83.
31. Evans DL, Dive C. Effects of cisplatin on the induction of apoptosis in proliferating hepatoma cells and non proliferating immature thymocytes. Cancer Res 1993; 53: 2133-9.
32. Zarkeri ZA, Quaglino D, Latham T, Lockshin RA. Delayed internucleosomal DNA fragmentation in programmed cell death. FASEB J 1993; 7: 470-8.
33. Brown DG, Sun XM, Cohen GM. Dexamethasone-induced apoptosis involves cleavage of DNA to larger fragments prior to internucleosomal fragmentation. J Biol Chem 1993; 268: 3037-9.
34. Munn DH, Ball AC, Song D, Wrenn RW, Throckmorton DC. Activation induced apoptosis in human macrophages: developmental regulation of a novel cell death pathway by macrophage colony-stimulating factor and interferon-γ. J Exp Med 1995; 181: 127-36.
35. Thompson CB. Apoptosis in the pathogensis and treatment of disease. Science 1995; 267: 1456-62.
36. Buttke TM, Sandstrom PA. Oxidative stress as a mediator of apoptosis. Immunol Today 1994; 15: 7-10.
37. Cohen GM, Sun XM, Snowden RT, Dinsdale D, Skilleter DN. Key morphological features of apoptosis may occur in the absence of internucleosomal DNA fragmentation. Biochem J 1992; 286: 331-4.
38. Cerami A. Inflammatory cytokines. Clin Immunol Immunopathol 1992; 62: S3-10.
39. Car BD, Eng VM, Schnyder B, et al. Interferon gamma-receptor deficient mice are resistant to endotoxic shock. J Exp Med 1994; 179: 1437-44.