The soluble extracellular portion of the human interferon-γ receptor is a valid substitute for evaluating binding characteristics and for neutralizing the biological activity of this cytokine

International Journal of Biochemistry and Cell Biology

Volumn 30, Issue 4, 1998, Pages 505-516

  Michiels, Lieve ^a   Haelewyn, Joost ^a   Proost, Paul ^b   De Ley, Marc ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

BIAcore; Binding; Eucaryotic expression; Interferon receptor

Indexed keywords

CYTOKINE; DNA FRAGMENT; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; HYBRID PROTEIN;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CROSS LINKING; ENZYME LINKED IMMUNOSORBENT ASSAY; GLYCOSYLATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IONIC STRENGTH; MASS SPECTROMETRY; MOUSE; NONHUMAN; ONCOGENE C MYC; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; RADIOIMMUNOASSAY; RECEPTOR BINDING;

ANIMALS; BINDING SITES; HUMANS; INTERFERON TYPE II; MICE; PROTO-ONCOGENE PROTEINS C-MYC; RADIOLIGAND ASSAY; RECEPTORS, INTERFERON; RECOMBINANT FUSION PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA; EUKARYOTA; MAMMALIA;

EID: 0031777578     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(98)00004-1     Document Type: Article

References (34)

1. Farrar M.A., Schreiber R.D. The molecular cell biology of interferon-γ and its receptor. Annu. Rev. Immunol. 11:1993;571-611.
2. Sen G.C., Lengyel P. The interferon system: a bird eye view of its biochemistry. J. Biol. Chem. 267:1992;5017-5020.
3. Ealick S.E., Cook W.J., Vijay-Kumar S., Carson M., Nagabhusan T.L., Trotta P.P., Bugg C.E. Three-dimensional structure of recombinant human interferon-γ Science. 252:1991;698-701.
4. van Loon A.P.G.M., Ozmen L., Fountoulakis M., Kania M., Haiker M., Garotta G. High-affinity receptor for interferon-gamma (IFN-γ), a ubiquitous protein occuring in different molecular forms on human cells: blood monocytes and eleven different cell lines have the same IFN-γ receptor protein. J. Leukocyte Biol. 49:1991;462-473.
5. Aguet M., Dembic Z., Merlin G. Molecular cloning and expression of the human interferon-gamma receptor. Cell. 55:1988;273-280.
6. Gray P.W., Leong S., Fennie E.H., Farrar M.A., Pingel J.T., Fernandez-Luna J., Schreiber R.D. Cloning and expression of the cDNA for the murine interferon-γ receptor. Proc. Natl. Acad. Sci. USA. 86:1989;8497-8501.
7. Garotta G., Ozmen L., Fountoulakis M., Dembic Z., van Loon A.P.G.M., Stüber D. Human interferon-γ receptor: Mapping of epitopes recognized by neutralizing antibodies using native and recombinant receptor proteins. J. Biol. Chem. 265:1990;6908-6915.
8. Gibbs V.C., Williams S.R., Gray P.W., Schreiber R.D., Pennicia D., Rice G., Goeddel D.V. The extracellular domain of the human interferon gamma receptor interacts with a species-specific signal transducer. Mol. Cell. Biol. 11:1991;5860-5866.
9. Hibino Y., Kumar C.S., Mariano T.M., Lai D., Pestka S. Chimeric interferon-γ receptors demonstrate that an accessory factor required for activity interacts with the extracellular domain. J. Biol. Chem. 267:1992;3741-3749.
10. Jung V., Rashidbaigi A., Jones C., Tischfield J.A., Shows T.B., Pestka S. Human chromosomes 6 and 21 are required for sensitivity to human interferon-γ Proc. Natl. Acad. Sci. USA. 84:1987;4154-4155.
11. Soh J., Donnelly R.J., Mariano T.M., Cook J.R., Schwartz B., Pestka S. Identification of a yeast artificial chromosome clone encoding an accessory factor for the human interferon γ receptor: Evidence for multiple accessory factors. Proc. Natl. Acad. Sci. USA. 90:1993;8737-8741.
12. Cook J.R., Emanuel S. L, Donnelly R.J., Soh J., Mariano T.M., Schwartz B., Rhee S., Pestka S. Sublocalization of the human interferon-γ receptor accessory factor gene and characterization of accessory factor activity by yeast artificial chromosomal fragmentation. J. Biol. Chem. 269:1994;7013-7018.
13. Soh J., Donnelly R.J., Kotenko S., Mariano T.M., Cook J.R., Wang N., Emanuel S., Schwartz B., Miki T., Pestka S. Identification and sequence of an accessory factor required for activation of the human interferon γ receptor. Cell. 76:1994;793-802.
14. Kotenko S.V., Izotova L.S., Pollack B.P., Mariano T.M., Donnelly R.J., Muthukumaran G., Cook J.R., Garotta G., Silvennoinen O., Ihle J.N., Pestka S. Interaction between the components of the interferon γ receptor complex. J. Biol. Chem. 270:1995;20915-20921.
15. Walter M.R., Windsor W.T., Nagabhushan T.L., Lundell D.J., Lunn C.A., Zauodny P.J., Narula S.K. Crystal structure of a complex between interferon-γ and its soluble high-affinity receptor. Nature. 376:1995;230-235.
16. Fountoulakis M., Juranville J.-F., Stüber D., Weibel E.K., Garotta G. Purification and characterization of a soluble interferon-γ receptor expressed in Escherichia coli. J. Biol. Chem. 265:1990;13268-13275.
17. Gentz R., Hayes A., Grau N., Fountoulakis M., Lahm H.-W., Ozmen L., Garotta G. Analysis of soluble human and mouse IFN-γ receptors expressed in eukaryotic cells. Eur. J. Biochem. 210:1992;545-554.
18. Shulmann M., Wilde C.D., Köhler G. A better cell line for making hybridomas secreting specific antibodies. Nature. 276:1978;269.
19. Oi V.T., Morrison S.L., Herzenberg L.A., Berg P. Immunoglobulin gene expression in transformed lymphoid cells. Proc. Natl. Acad. Sci. USA. 80:1983;825-829.
20. Giard D.J., Aaronson S.A., Todaro G.J., Arnstein P., Kershey J.M., Dosik H., Parks W.P. In vitro cultivation of human tumory: establishment of cell lines derived from series of solid tumors. J. Natl. Cancer Inst. 51:1973;1417-1423.
21. B.G. Sahagan, H. Dorai, J. Saltzgaber-Muller, F. Tonegurro, C.A. Guindon, S.P. Lilly, K.W. McDonald, D.V. Morrissey, B.A. Stone, G.L. Davis, P.K. McIntosh, G.P. Moore, A genetically engineered murine/human chimeric antibody retains specificity for human tumor-associated antigen J. Immunol. 137 (1986) 1066-1074.
22. Haelewyn J., De Ley M. A rapid single step purification method for human interferon-γ from isolated Escherichia coli inclusion bodies. Biochem. Mol. Biol. Int. 37:1995;1163-1171.
23. Wietzerbin J., Gaudelet C., Aguet M., Falcoff E. Binding and cross-linking of recombinant mouse interferon-γ to receptors in mouse leukemic L1210 cells; interferon-γ internalization and receptor down-regulation. J. Immunol. 136:1986;2451-2455.
24. Evan G.I., Lewis G.K., Ramsay G., Bishop J.M. Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol. Cell. Biol. 5:1985;3610-3616.
25. Hendricks M.B., Banker M.J., McLaughlin M. A high-efficiency vector for expression of foreign genes in myeloma cells. Gene. 64:1988;43-51.
26. Birnboim H.C., Doly J. A rapid alkaline extraction procedure for screening recombinant plasmide DNA. Nucleic Acids Res. 7:1979;1519.
27. T. Maniatis, E.F. Fritsch, J. Sambrook, in: Molecular Cloning. A Laboratory Manual. Cold Spring Harbor Laboratory Press, New York, 1989.
28. Sanger F., Nicklen S., Coulson A.R. DNA sequencing with chain-termination inhibitors. Proc. Natl. Acad. Sci. USA. 74:1977;5463-5467.
29. Laemmli U.K. Charge of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
30. D. Walker, Silverstaining in gel electrophoresis, Lab. Tech. (1987) 12-16.
31. Gershoni J.M., Palade G.E. Protein blotting: principles and application. Anal. Biochem. 131:1983;1-15.
32. L. Stryer, in: Biochemistry, W.H. Freeman and Company, New York, 1988.
33. Fountoulakis M., Gentz R. Effect of glycosylation on properties of soluble interferon gamma receptors produced in prokaryotic and eukaryotic expression systems. BioTechnology. 10:1992;1143-1147.
34. Dijkmans R., Tobback M., Beuken E., Van Damme J., Billiau A. Molecular cloning of the baboon interferon-gamma cDNA. Lymphokine Res. 9:1990;345-354.