In vitro release of colchicine using poly(phosphazenes): The development of delivery systems for musculoskeletal use

Pharmaceutical Development and Technology

Volumn 3, Issue 1, 1998, Pages 55-62

  Ibim, Sobrasua M ^a,b   El Amin, Saadiq F ^c   Goad, Mary E P ^d   Ambrosio, Archel M A ^c   Allcock, Harry R ^e   Laurencin, Cato T ^c,f  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b Morris Brown College   (United States)

^c DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^d Biodevelopment Laboratories Incorporated   (United States)

^e PENNSYLVANIA STATE UNIVERSITY   (United States)

^f Drexel University   (United States)

Author keywords

Colchicine; Delivery; Osteoblasts; Poly(phosphazene); Polymer; Skeletal

Indexed keywords

COLCHICINE; PHOSPHAZENE DERIVATIVE; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; BIOAVAILABILITY; CELL KINETICS; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG RELEASE; INTRAARTICULAR DRUG ADMINISTRATION; OSTEOBLAST; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY;

EID: 0031777551     PISSN: 10837450     EISSN: None     Source Type: Journal    
DOI: 10.3109/10837459809028479     Document Type: Article

References (23)

1. S. L. Wallace and J. Z. Singer, Review: systemic toxicity associated with the intravenous administration of colchicine - guidelines for use, J. Rheumatol., 15, 495-498 (1988).
2. Y.-H. Chang, S. L. Silverman, and H. E. Paulus, Colchicine, in Drugs for Rheumatoid Disease (H. Paulus, D. Furst, and S. Dromgoole, eds.), Churchill, Livingstone, New York, 1987, pp. 431-442.
3. M. M. Kaplan, D. Ailing, H. J. Zimmerman, H. J. Wolke, R. A. Sepersky, G. S. Hirsch, G. H. Elta, R. A. Glick, and K. A. Eagen, A prospective trial of colchicine for primary biliary cirrhosis, N. Engl. J. Med., 315, 1448-1454 (1986).
4. W. N. Robert, M. H. Liang, and S. H. Stern, Colchicine in acute gout. Reassessment of risks and benefits, JAMA, 257, 1920-1922 (1987).
5. S. E. Malawista, Colchicine: a common mechanism for its anti-inflammatory and anti-mitotic effects, Arthritis Rheum., 11, 191-197 (1968).
6. G. G. Borisy and E. W. Taylor, The mechanism of action of colchicine. Binding of colchicine-3H to cellular protein, J. Cell Biol., 34, 525-533 (1967).
7. L. Wilson and M. Friedkin, The biochemical events of mitosis. II. The in vivo and in vitro binding of colchicine in grasshopper embryos and its possible relation to inhibition of mitosis, Biochemistry, 6, 3126-3135 (1967).
8. M. Duijndam-van den Berge and J. G. Goekoop, Lymphocyte concanavalin A capping: a similarity between Down's syndrome and early onset primary degenerative dementia, J. Neurol. Neurosurg. Psychiatry, 49, 595-598 (1986).
9. T. K. Fu, S. S. Matsuyama, J. O. Kessler, and L. F. Jarvick, Philothermal response microtubules and dementia, Neurobiol. Aging, 7, 41-43 (1968).
10. K. Iqbal, I. Grundke-Iqbal, T. Zaidi, P. A. Merz, G. Y.Wen, S. S. Shaikh, and H. M. Wisneiwski, Defective brain microtubule assembly in Alzheimer's disease, Lancet, 2(8504), 421-426 (1986).
11. S. S. Matsuyama and L. F. Jarvick, Hypothesis: microtubules, a key to Alzheimer disease, Proc. Natl. Acad. Sci. USA, 86, 8152-8156 (1989).
12. E. M. Ruiz, C. A. Ramirez, M. A. Aponte, and G. V. Barbosa-Canovas, Degradation of poly[bis(glycine ethyl ester)phosphazene] in aqueous media, Biomaterials, 14, 491-496 (1993).
13. P. Wuthrich, B. K. Ng, K. V. Fritzinger, and J. Heller, Pulsatile and delayed release of lysozymes from ointment-like poly(orthoesters), J. Controlled Release, 21, 191-200 (1992).
14. S. Cohen, T. Yoshioka, M. Lucarelli, L. H. Hwang, and R. S. Langer, Controlled delivery systems for proteins based on poly(lactic/glycolic acid), Pharm. Res., 8, 713-720 (1991).
15. C. T. Laurencin, H. J. Koh, R. H. Neenan, H. R. Allcock, and R. Langer, Controlled release using a new bioerodible polyphosphazene matrix system, J. Biomed. Mater. Res., 21, 1231-1246 (1987).
16. H. R. Allcock, T. J. Fuller, D. P. Mack, K. Matsumura, and K. M. Smeltz, Synthesis of poly[(amino acid alkyl ester) phosphazenes], Macromolecules, 10, 824-830 (1977).
17. H. R. Allcock and T. J Fuller. Synthesis and hydrolysis of hexakis(imidazolyl) cyclotriphosphazene, J. Am. Chem. Soc., 103, 2250-2256 (1981).
18. C. W. J. Grolleman, A. C. deVisser, J. G. C. Wolke, H. van der Goot, and H. Timmerman, Studies on a bioerodible drug carrier system based on PPHOS: Part I. Synthesis, J. Controlled Release, 3, 143-154 (1986).
19. H. M. Elgendy, M. E. Norman, A. R Keaton, and C. T. Laurencin, Osteoblast-like cell (MC3T3-E1) proliferation on bioerodible polymers: an approach towards the development of a bone-bioerodible polymer composite material, Biomaterials, 14(4), 263-268 (1992).
20. I. Guttman, S. S. Wilks, and J. S. Hunter, Introductory Engineering Statistics, John Wiley, New York, 1982.
21. C. T. Laurencin, M. E. Norman, H. M. Elgendy, S. F. El-Amin, H. R. Allcock, S. R. Pucher, and A. A. Ambrosio, Use of polyphosphazenes for skeletal regeneration, J. Biomed. Mater. Res., 27, 963-73 (1993).
22. S. M. Ibim, A. Ambrosio, D. Larrier, H. R. Allcock, and C. T. Laurencin, Controlled macromolecule release from poly(phosphazene) matrices, J. Controlled Release, 40, 31-39 (1996).
23. Drugs used in gout and hyperuricemia, in AMA Drug Evaluations, American Medical Association, Chicago, IL, 1983, pp. 139-152.