trithorax and the regulation of homeotic gene expression in Drosophila: A historical perspective

International Journal of Developmental Biology

Volumn 42, Issue 3, 1998, Pages 423-429

  Ingham, Philip W ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Cell heredity; Drosophila; Homeotic; Trithorax

Indexed keywords

BINDING PROTEIN; DNA;

ABDOMEN; CHROMATIN; DNA SEQUENCE; DROSOPHILA; GENE EXPRESSION REGULATION; GENE MUTATION; HOMEOBOX; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; REVIEW; THORAX;

ANIMALS; DEVELOPMENTAL BIOLOGY; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, HOMEOBOX; HISTORY, 20TH CENTURY; MOLECULAR BIOLOGY; TRANSCRIPTION FACTORS;

ANIMALIA; HEXAPODA;

EID: 0031777172     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (45)

1. ASTAUROFF, (1930) Analyse der erblichen Störungsfälle der bilateralen Symmetrie im Zusammenhang mit der selbstandigen Variabilitat ahnlicher Strukturen Z. indukt. Abstamm. Vererb 55: 183-262.
2. BOWNES, M. and SEILER, M. (1977) Developmental effects of exposing Drosophila embryos to ether. J. Exp. Zool 199: 9-24.
3. BREEN, T. and HARTE, P. (1993). trithorax regulates multiple homeotic genes in the Bithorax and Antennapedia complexes and exerts different issue-specific, parasegment-specific an promoter-specific effects on each. Development. 117: 119-134
4. BREEN, T , CHINWALLA, V. and HARTE, P (1995). trithorax is required to maintain engrailed expression in a subset of engrailed-expressing cells. Mech. Dev. 52: 89-98.
5. CAPDEVILA, M and GARCÍA-BELLIDO, A. (1974) Development and genetic analysis of bithorax phenocopies in Drosophila, Nature. 250: 500-502.
6. CAPDEVILA, M. and GARCÍA-BELLIDO, A (1978). Phenocopies of bithorax mutants. Genetic and developmental analysis. Roux Arch Dev Biol. 185: 105-126
7. CAPDEVILA, M and GARCÍA-BELLIDO, A. (1981). Genes involvd in the activation of the Bithorax complex of Drosophila. Roux Arch. Dev. Biol. 190: 339-350.
8. CASTELLI-GAIR, J. and GARCÍA-BELLIDO, A. (1990). Interactions of the Polycomb and trithorax with cis regulatory regions of Ultrabithorax during the development of Drosophila melanogaster. EMBO J. 9: 4267-4275.
9. CHANG, Y., KING, B., O'CONNOR, M , MAZO A. and HUANG, D. (1995). Functional reconstruction of trans regulation of the Ultrabithorax - promoter by the products of two antagonistic genes, trithorax and Polycomb Mol. Cell. Biol. 15: 6601-6612.
10. CHINWALLA, V., JANE, E. and HARTE, P (1995). The Drosophila trithorax protein binds to specific chromosomal sites and is co-localized with polycomb at many sites. EMBO J 14: 2056-2065
11. DENELL, R., HUMMELS, K., WAKIMOTO, B. and KAUFMAN, T. (1981). Developmental Studies of Lethality Associated with the Antennapedia Gene Complex in Drosophila melanogaster. Dev. Biol 81: 43-50.
12. DJABALI, M , SELLERI, L., PARRY, P , BOWER, M., YOUNG, B. and EVANS, G (1992). A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukemias. Nature Genet 2: 113
13. GARCÍA-BELLIDO, A (1975) Genetic control of wing disc development in Drosophila. In Cell Patterning (Ed. S. Brenner) Ciba Foundation Symposium 29 Associated Scientific Publishers Amsterdam, pp 161-177.
14. GARCÍA-BELLIDO, A (1977). Homoeotic and atavic mutations in insects Am. Zool. 17: 613-629
15. GARCÍA-BELLIDO, A., RIPOLL P. and MORATA, G (1973). Developmental compartmentalisation of the wing disc of Drosophila. Nature New Biol. 245: 251-253
16. GARCÍA-BELLIDO, A., RIPOLL P. and MORATA, G. (1976). Developmental compartmentalization in the dorsal mesothoracic disc of Drosophila. Dev. Biol 48: 132-147.
17. GINDHART, J and KAUFMAN, T. (1995) Identification of Polycomb and trithorax group responsive elements in the regulatory region of the Drosophila homeotic gene Sex combs reduced. Genetics 139: 797-814
18. GLOOR, H (1947). Phänokopie-Versuche mit Àtheran Drosophila. Rev Suisse Zool. 54: 637-712.
19. INGHAM, P W (1981 ). trithorax: A new homoeotic mutation of Drosophila melanogaster. II Roux Arch. Dev Biol 190: 365-369
20. INGHAM, P.W (1983) Differential expression of bithorax complex genes in the absence of the extra sex combs and trithora genes Nature 306 591-593.
21. INGHAM, P.W (1985). A clonal analysis of the trithorax gene in Drosophila. J. Embryol. Exp. Morphol. 89: 349-365.
22. INGHAM, P.W. (1988). The molecular genetics of embryonic pattern formation in Drosophila Nature 335: 25-34.
23. INGHAM, P W. and MARTINEZ-ARIAS, A (1986). The correct activation of Antennapedia and bithorax complex genes requires the fushi-tarazu gene. Nature 324: 592
24. INGHAM, P W. and WHITTLE, R (1980) trithorax: a new homoeotic mutation of Drosophila melanogaster causing transformations of abdominal and thoracic imaginai segments. Mol. Gen. Genet 179: 607-614
25. INGHAM, P.W., BAKER N. E and MARTINEZ-ARIAS, A (1988) Regulation of segment polarity genes in the Drosophila blastoderm by fushi-tarazu and even-skipped. Nature. 331: 73-75.
26. INGHAM, P.W., MARTINEZ-ARIAS, A. LAWRENCE, P.A. and HOWARD, K. (1985). Expression of engrailed in the parasegment of Drosophila Nature. 317: 634-636.
27. KUZIN, B , TILLIB, S , SEDKOV, Y., MIZROKHI, L. and MAZO, A. (1994). The drosophila trithorax gene encodes a chromosomal protein and directly regulates the region-specific homeotic gene fork head. Genes Dev 8: 2478-2490.
28. LAWRENCE, P.A and MORATA, G. (1976). The compartment hypothesis. In Insect Development (Ed. P.A. Lawrence) Blackwell Scientific Publications, Oxford, pp. 132-149.
29. LEWIS, E.B. (1963). Genes and developemtal pathways. Am. Zool. 3: 33-56.
30. LEWIS, E.B. (1964). Genetic control and regulation of developmental pathways. In Role of Chromosomes in Development (Ed. M. Locke) Academic Press, New York, pp 232-251.
31. LEWIS, E.B. (1978). A gene complex controlling segmentation in Drosophila. Nature. 276 565-570.
32. LEWIS, R., KAUFMAN, T., DENELL, R. and TALLERICO, P. (1980a). Genetic analysis of the Antennapedia Gene Complex (ANT-C) and adjacent chromosomal regions of Drosophila melanogaster I Polytene chromosome segemnts 84B-D. Genetics. 95: 367-381
33. LEWIS, R., WAKIMOTO, B., DENELL, R. and KAUFMAN, T. (1980b). Genetic analysis of the Antennapedia Gene Complex (ANT-C) and adjacent chromosomal regions of Drosophila melanogaster. II Polytene chromosome segemnts 84A-84B1,2 Genetics. 95 383-397.
34. LINDSLEY, D. and GRELL, E. (1968). Genetic variations of Drosophila melanogaster. Carnegie Inst Washington Publ. No 627.
35. MAZO, A., HUNG, D-H , MOZER, B and DAWID, I. (1990). The trithorax gene, a trans-acting regulator of the bithorax complex in Drosophila, encodes a protein with zinc-binding domains Proc Natl. Acad Sci. USA. 87: 2112-2116.
36. MORATA, G and KERRIDGE, S. (1981). Sequential functions of the Bithorax complex in Drosophila. Nature 290: 778-781
37. MORATA, G. and LAWRENCE, P A. (1975). Control of compartment development by the engrailed gene in Drosophila. Nature 255: 624-627.
38. NÜSSLEIN-VOLHARD, C and WIESCHAUS, E. (1980). Mutations affecting segment number and polarity in Drosophila Nature 287: 795-801.
39. SEDKOV, Y., TILLIB, S., MIZROKHI, L and MAZO, A. (1994). The Bithorax complex is regulated by trithorax earlier during Drosophila embryogenesis than is the Antennapedia complex, correlating with a bithorax-like expression pattern of distinct early trithorax transcripts. Development. 120: 1907-1917.
40. SIMON, J., CHIANG, A and BENDER, W (1992). Ten different Polycomb group genes are required for spatial control of the abdA and AbdB homeotic products. Development 114: 493-505.
41. STRUHL, G. (1981). A gene product required for correct initiation of segmental determination in Drosophila. Nature 293: 36-41.
42. STRUHL, G. and AKAM, M. (1985) Altered distributions of Ultrabithorax transcripts in extra sex combs mutant embryos of Drosophila EMBO J 4: 3259-3264.
43. WADDINGTON, C. (1956). Genetic assimilation of the bithorax phenotype. Evolution 10: 1-13.
44. WAKIMOTO, B and KAUFMAN, T. (1981). Analysis of Larval Segmentation in Lethal Genotypes Associated with the Antennapedia Gene Complex in Drosophila melanogaster. Dev. Biol 81: 51-64.
45. YU, B., HESS, J , HORNING, S., BROWN, G. and KORSMEYER., S. (1995). Altered Hox expression and segmental identity in Mll mutant mice. Nature 378: 505-508