Colonic mucin release in response to immobilization stress is mast cell dependent

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 274, Issue 6 37-6, 1998, Pages

  Castagliuolo, Ignazio ^a   Wershil, Barry K ^a,b   Karalis, Katia ^a,b   Pasha, Asiya ^a   Nikulasson, Sigfus T ^c   Pothoulakis, Charalabos ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Central nervous system; Colonic motility; Hypothalamic pituitary adrenal axis; Mast cell deficient mice; Prostaglandin E2

Indexed keywords

MUCIN; PROSTAGLANDIN E2;

ANIMAL CELL; ARTICLE; CELL ACTIVITY; CENTRAL NERVOUS SYSTEM; DEGRANULATION; GOBLET CELL; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMOBILIZED CELL; INTESTINE TRANSIT TIME; MALE; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN BLOOD LEVEL; STATISTICAL ANALYSIS; STRESS;

EID: 0031776639     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1998.274.6.g1094     Document Type: Article

References (40)

1. Antoni, F. A. Hypothalamic control of adrenocorticotropin secretion: advances since the discovery of the 41-residue corticotropin-releasing factor. Endocr. Rev. 7: 351-378, 1986.
2. Bugajski, A. J., Z. Chlap, A. Gadek-Michalska, and J. Bugajski. Effect of isolation stress on brain mast cells and brain histamine levels in rats. Agents Actions 41: 75-76, 1994.
3. Carraway, R., D. E. Cochrane, J. B. Lansman, S. E. Leeman, B. M. Paterson, and H. J. Welch. Neurotensin stimulates exocytotic histamine secretion from rat mast cells and elevates plasma histamine levels. J. Physlol. Paris 323: 403-414, 1982.
4. Carraway, R., and S. E. Leeman. Characterization of radioimmuno-assayable neurotensin in the rat. Its differential distribution in the central nervous system, small intestine and stomach. J. Biol. Chem. 251: 7045-7052, 1976.
5. Castagliuolo, I., J. T. LaMont, R. Letourneau, C. P. Kelly, J. C. O'Keane, A. Jaffer, T. C. Theoharides, and C. Pothoulakis. Neuronal involvement in the intestinal effects of Closiridium difficile toxin A and Vibrio cholera enterotoxin. Gastroenterology 107: 657-665, 1994.
6. Castagliuolo, I., J. T. LaMont, B. S. Qiu, S. M. Flemming, K. R. Bhaskar, S. T. Nikulasson, C. Kornetsky, and C. Pothoulakis. Acute stress causes mucin release from rat colon: role of corticotropin releasing factor and mast cells. Am. J. Physiol. 271 (Gastrointest. Liver Physiol. 34): G884-G892, 1996.
7. Castagliuolo, I., S. E. Leeman, E. Bartolak-Suki, S. T. Nikulasson, B. S. Qiu, R. E. Carraway, and C. Pothoulakis. A neurotensin antagonist, SR 48692 inhibits colonie responses to immobilization stress in rats. Proc. Natl. Acad. Sci. USA 93: 12611-12615, 1996.
8. Farthing, M. J. G. Irritable bowel, irritable body, or irritable brain? Br. Med. J. 310: 171-175, 1995.
9. 2+ and PKC. Am. J. Physiol. 266 (Gastrointest. Liver Physiol. 29): G606-G612, 1994.
10. Galli, S. J., E. N. Geissler, B. K. Wershil, J. R. Gordon, M. Tsai, and I. Hammel. Insights into mast cell development and function derived from analyses of mice carrying mutations at beige, W/c-kit, or Sl/SCF (c-kit ligand) loci. In: The Role of Mast Cells in Health and Disease, edited by M. A. Kaliner and D. D. Metcalfe. New York: Marcel Dekker, 1992, p. 129-202.
11. Galli, S. J., K. M. Zsebo, and E. N. Geissler. The kit ligand, stem cell factor. Adv. Immunol. 55: 1-96, 1994.
12. Hinson, J. P., G. P. Vinson, S. Kapas, and R. Teja. The relationship between adrenal vascular events and steroid secretion: the role of mast cells and endothelin. J. Steroid Biochem. Mol. Biol. 40: 381-389, 1991.
13. Hinson, J. P., G. P. Vinson, J. Pudney, and B. J. Whitehouse. Adrenal mast cells modulate vascular and secretory responses in the intact adrenal gland of the rat. J. Endocrinol. 121: 253-260, 1989.
14. Huizinga, L., L. Thuneberg, M. Kluppel, L. Malysz, H. B. Mikkelsen, and A. Bernstein. Kit/W gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature 373: 347-349, 1995.
15. LaMorte, W. W., J. T. LaMont, M. L. Booker, T. E. Scott, and B. Turner. Gallbladder prostaglandins and lysophospholipids as mediators of mucin secretion during cholelithiasis. Am. J. Physiol. 251 (Gastrointest. Liver Physiol. 14): G701-G709, 1986.
16. Lenz, H. J. Regulation of duodenal bicarbonate secretion during stress by corticotropin-releasing factor and β-endorphin. Proc. Natl. Acad. Sci. USA 86: 1417-1420, 1989.
17. Libel, R., W. L. Biddle, and P. B. Miner. Evaluation of anorectal physiology in patients with increased mast cells. Dig. Dis. Sci. 38: 877-881, 1993.
18. MacQueen, G., J. Marshall, M. Perdue, S. Siegel, and J. Bienenstock. Pavlovian conditioning of rat mucosal mast cells to secrete rat mast cell protease II. Science 243: 83-85, 1989.
19. Monnikes, H., B. G. Schmidt, and Y. Taché. Psychological stress-induced accelerated colonic transit in rats involves hypothalamic corticotropin-releasing factor. Gastroenterology 104: 716-723, 1993.
20. v mice. J. Exp. Med. 162: 1025-1043, 1985.
21. Pang, X., W. Boucher, G. Triadafilopoulos, G. R. Sant, and T. C. Theoharides. Mast cells (MC) and substance P (SP)-positive nerve involvement in a patient with both irritable bowel syndrome (IBS) and interstitial cystitis (IC). Urology 47: 436-438, 1996.
22. v mice by bone marrow transplantation. J. Clin. Invest. 87: 687-693, 1991.
23. Pothoulakis, C., F. Karmeli, C. P. Kelly, R. Eliakim, M. A. Joshi, J. C. O'Keane, I. Castagliuolo, J. T. LaMont, and D. Rachmilewitz. Ketotifen inhibits Clostridium difficile toxin A-induced enteritis in rat ileum. Gastroenterology 105: 701-707, 1993.
24. Puddington, L., S. Olson, and L. Lefrancois. Interactions between stem cell factor and c-kit are required for intestinal immune system homeostasis. Immunity 1: 733-739, 1994.
25. Russel, M., K. A. Dark, R. W. Cummins, G. Ellman, E. Callaway, and H. V. S. Peeke. Learned histamine release. Science 225: 733-734, 1984.
26. Santos, J., E. Saperas, M. Mourelle, M. Antolin, C. Nogueiras, and J.-R. Malagelada. The central nervous system (CNS) activates mast cell-mediated inflammation in humans (Abstract). Gastroenterology 112: A1184, 1997.
27. Saunders, P. R., U. Kosecka, D. M. McKay, and M. H. Perdue. Acute stressors stimulate ion secretion and increase epithelial permeability in rat intestine. Am. J. Physiol. 267 (Gastrointest. Liver Physiol. 30): G794-G799, 1994.
28. 2+-dependent and -independent secretagogue action on gastric mucus secretion in rabbit mucosal expiants. Am. J. Physiol. 256 (Gastrointest. Liver Physiol. 19): G739-G746, 1989.
29. Spanos, C., X. Pang, K. Ligris, R. Letourneau, L. Alferes, N. Alexakos, G. R. Sant, and T. C. Theoharides. Stress-induced bladder mast cell activation: implications for interstitial cystitis. J. Urol. 157: 669-672, 1997.
30. Stead, R. H., R. F. Dixon, N. H. Bramwell, R. H. Ridell, and J. Bienenstock. Mast cells are closely apposed to nerves in the human gastrointestinal mucosa. Gastroenterology 97: 575-585, 1989.
31. Stead, R. H., M. Tomioka, G. Quinonez, G. T. Simon, S. Y. Felten, and J. Bienenstock. Intestinal mucosal mast cells in normal and nematode-infected rat intestines are in intimate contact with peptidergic nerves. Proc. Natl. Acad. Sci. USA 84: 2975-2979, 1987.
32. Theoharides, T. C., C. Spanos, X. Pang, L. Alferes, K. Ligris, R. Letourneau, J. J. Rozniecki, E. Webster, and G. P. Chrousos. Stress-induced intracranial mast cell degranulation: a corticotropin-releasing hormone-mediated effect. Endocrinology 136: 5745-5750, 1995.
33. Tuncel, N., F. Gurer, E. Aral, K. Uzuner, Y. Aydin, and C. Baycu. The effect of vasoactive intestinal peptide on mast invasion/degranulation in testicular interstitium of immobilized + cold stressed and β-endorphin-treated rats. Peptides 17: 817-821, 1996.
34. Vale, W., and M. Greer. Corticotropin-releasing factor. Fed. Proc. 44, pt. 2, 1985.
35. Vale, W., J. Spiess, C. Rivier, and J. Rivier. Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and β-endorphin. Science 213: 1394-1397, 1981.
36. Wang, L., A. M. Stanisz, B. K. Wershil, S. J. Galli, and M. H. Perdue. Substance P induces ion secretion in mouse small intestine through effects on enteric nerves and mast cells. Am. J. Physiol. 269 (Gastrointest. Liver Physiol. 32): G85-G92, 1995.
37. Wershil, B. K. The role of mast cells and basophils in gastrointestinal inflammation. Chem. Immunol. 62: 204-238, 1992.
38. Weston, A. P., W. L. Biddle, P. S. Bathia, and P. B. Miner, Jr. Terminal ileal mucosal mast cells in irritable bowel syndrome. Dig. Dis. Sci. 38: 1590-1595, 1993.
39. Williams, C. L., R. G. Villar, J. M. Peterson, and T. F. Burks. Stress-induced changes in intestinal transit in the rat: a model for irritable bowel syndrome. Gastroenterology 94: 611-621, 1988.
40. Yano, H., B. K. Wershil, N. Arizano, and S. J. Galli. Substance P-induced augmentation of cutaneous vascular permeability and granulocyte infiltration in mice is mast cell dependent. J. Clin. Invest. 84: 1276-1286, 1989.