Association of specific LDL receptor gene mutations with differential plasma lipoprotein response to simvastatin in young French Canadians with heterozygous familial hypercholesterolemia

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 18, Issue 6, 1998, Pages 1007-1012

  Couture, Patrick ^a,b   Brun, Louis D ^b   Szots, François ^c   Lelièvre, Michel ^c   Gaudet, Daniel ^d   Després, Jean Pierre ^b   Simard, Jacques ^a   Lupien, Paul J ^b   Gagné, Claude ^b,c  

^a Lab of Molecular Endocrinology   (Canada)

^b Lipid Research Center   (Canada)

^c LAVAL UNIVERSITY   (Canada)

^d CHICOUTIMI HOSPITAL   (Canada)

Author keywords

Children; Familial hypercholesterolemia; French Canadian; LDL receptor gene mutation; Simvastatin

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN RECEPTOR; SIMVASTATIN;

ADOLESCENT; ARTICLE; CANADA; CHOLESTEROL BLOOD LEVEL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; FEMALE; GENE MUTATION; HUMAN; HYPERCHOLESTEROLEMIA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

EID: 0031776536     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.18.6.1007     Document Type: Article

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