A cluster of cases of severe cardiotoxicity among kala-azar patients treated with a high-osmolarity lot of sodium antimony gluconate

American Journal of Tropical Medicine and Hygiene

Volumn 59, Issue 1, 1998, Pages 139-143

  Sundar, Shyam ^a   Sinha, Prabhat R ^a   Agrawal, Nutan K ^a   Srivastava, Rakesh ^a   Rainey, Petrie M ^b   Berman, Jonathan D ^c   Murray, Henry W ^d   Singh, Vijay P ^a  

^a BANARAS HINDU UNIVERSITY   (India)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMONY GLUCONATE;

ADULT; ARTICLE; CARDIOTOXICITY; CASE REPORT; CONGESTIVE HEART FAILURE; DRUG INDUCED DISEASE; DRUG MANUFACTURE; DRUG STRUCTURE; FEMALE; HEART VENTRICLE EXTRASYSTOLE; HEART VENTRICLE TACHYCARDIA; HUMAN; HUMAN TISSUE; LEISHMANIASIS; MALE; OSMOLARITY; QT INTERVAL;

EID: 0031776345     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.1998.59.139     Document Type: Article

References (18)

1. Kiri R, Sati ME, 1947. Observations on the use of sodium antimony gluconate (sodium stibogluconate) in the treatment of kala-azar. Ann Trop Med Parasitol 41: 14-21.
2. Manson-Bahr PEC, Bell DR, eds, 1987. Visceral Leishmaniasis. Manson's Tropical Diseases. 19th edition, London: Bailliere Tindal, 87-113.
3. World Health Organization, 1984. The leishmaniases: report of a WHO expert committee. World Health Organ Tech Rep Ser 701.
4. World Health Organization. 1990. Control of leishmaniases: report of a WHO expert committee. World Health Organ Tech Rep Ser 793: 50-55.
5. Thakur CP, Kumar M, Pandey AK, 1993. Evaluation of efficacy of longer duration of therapy of fresh cases of kala-azar with sodium stibogluconate. Indian J Med Res 93 (A): 103-110.
6. Herwaldt BL, Berman JD, 1992. Recommendations for treating leishmaniasis with sodium stibogluconate (Pentostam) and review of pertinent clinical studies. Am J Trop Med Hyg 46: 296-306.
7. Navin TR, Arana BA, Arana FE, Berman JD, Chajon JF, 1992. Placebo-controlled clinical trial of sodium stibogluconate (Pentostam) versus ketoconazole for treating cutaneous leishmaniasis in Guatemala. J Infect Dis 165: 528-534.
8. Chulay JD, Spencer HC, Mugambi M, 1985. Electrocardiographic changes during treatment of leishmaniasis with pentavaient antimony (sodium stibogluconate). Am J Trop Med Hyg 34: 792-799.
9. Sundar S, Singh VP, Sharma S, Makharia MK, Murray HW, 1991. Response to interferon-γ plus antimony in Indian visceral leishmaniasis. J Infect Dis 176: 1117-1119.
10. Singh NKP, Sharma D, Jha TK, 1989. Kala-azar mortality in hospitalized cases in North Bihar, India. J Assoc Physicians India 37: 514-516.
11. Fisch C, 1984. Electrotardiography and vectorcardiography. Braunwald E. ed. Heart Disease. Second edition. Philadelphia: W. B. Saunders Co., 195-257.
12. Meyerburg RJ, Castellanos A., 1988. Cardiac arrest and sudden cardiac death. Braunwaid E, ed. Heart Disease. Philadelphia: W. B. Saunders, 742-777.
13. Roberts WL, Rainey PM, 1993. Antimony quantification in Leishmania by electrothermal atomic absorption spectroscopy. Anal Biochem 311: 1-6.
14. Thakur CP, Kumar M, Kumar P, Mishra BN, Pandey AK, 1988. Rationalisation of regimens of treatment of kala-azar with sodium stibogluconate in India: a randomised study. Br Med J 296: 1557-1561.
15. Berman JD, Grogl M, 1988. Leishmania mexicana: chemistry and biochemistry of sodium stibogluconate (Pentostam). Exp Parasitol 67: 96-103.
16. Roberts WL, Rainey PM, 1993, Antileishmanial activity of sodium stibogluconate fractions. Antimicrob Agents Chemother 37: 1842-1846.
17. Winship KA, 1987. Toxicity of antimony and its compounds. Adv Drug React Acute Poison Rev 2: 67-90.
18. Franco MA, Barbosa AC, Rath S, Dorea JG, 1995. Antimony oxidation states in antileishmanial drugs. Am J Trop Med Hyg 52: 435-437.