Influence of polytetrafluoroethylene on spheroid production by rotary processing

S.T.P. Pharma Sciences

Volumn 8, Issue 5, 1998, Pages 297-302

  Liew, C V ^a   Wan, L S C ^a   Heng, P W S ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Material adhesion; Polytetrafluoroethylene; Rotary processor; Spheroid production; Spheroids; Spheronization

Indexed keywords

LACTOSE; MICROCRYSTALLINE CELLULOSE; POLITEF;

ADHESION; ARTICLE; DRUG COATING; DRUG FORMULATION; PARTICLE SIZE; SURFACE PROPERTY;

EID: 0031775741     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. ROBINSON R.L. and HOLLENBECK R.G. - Manufacture of spherical acetaminophen pellets: comparison of rotary processing with multiple-step extrusion and spheronization. -Pharm. Tech., 15, 48, 50-54, 56, 1991.
2. HENG P.W.S., WAN L.S.C. and LIEW C.V. - Reduction of formation of oversized particles during spheronization in a rotoprocessor. - National University of Singapore (NUS)/Japan Society for the Promotion of Science (JSPS) Seminar on the Advances in Pharmaceutical Sciences, Singapore, 8 to 10 December 1994, pp. 76-80.
3. VECCHIO C., BRUNI G. and GAZZANIGA A. - Preparation of indobufen pellets by using centrifugal rotary fluidized bed equipment without starting seeds. - Drug Dev. Ind, Pharm., 20, 1943-1956, 1994.
4. WAN L.S.C., HENG P.W.S. and LIEW C.V. - The role of moisture and gap air pressure in the formation of spherical granules by rotary processing. - Drug Dev. Ind. Pharm., 20, 2551-2561, 1994.
5. WAN L.S.C., HENG P.W.S. and LIEW C.V. - The influence of liquid spray rate and atomizing air pressure on the size of spray droplets and spheroids. - Int. J. Pharm., 118, 213-219, 1995.
6. HENG P.W.S., WAN L.S.C. and TAN Y.T.F. - Optimization of spheroid production by centrifugal rotary processing. - Int. J. Pharm., 143, 107-112, 1996.
7. VERTOMMEN J. and KINGET R. - The influence of five selected processing and formulation variables on the particle size, particle size distribution, and friability of pellets produced in a rotary processor. - Drug Dev. Ind. Pharm., 23, 39-46, 1997.
8. VERTOMMEN J. , ROMBAUT P. and KINGET R. - Shape and surface smoothness of pellets made in a rotary processor. - Int. J. Pharm., 146, 21-29, 1997.
9. KRISTENSEN H.G. - Agglomeration of powders. - Acta Pharm. Suec., 25, 187-204, 1988.
10. RITALA M., HOLM P., SCHAEFER T. and KRISTENSEN H.G. - Influence of liquid bonding strength on power consumption during granulation in a high-shear mixer. - Drug Dev. Ind. Pharm., 14, 1041-1060, 1988.
11. SCHAEFER T., HOLM P. and KRISTENSEN H.G. - Melt granulation in a laboratory scale high shear mixer. - Drug Dev. Ind. Pharm., 16, 1249-1277, 1990.
12. SCHAEFER T., HOLM P. and KRISTENSEN H.G. - Melt pelletization in a high shear mixer. I: Effects of process variables and binder. - Acta Pharm. Nord., 4, 133-140, 1992.
13. HOLM P. SCHAEFER T. and KRISTENSEN H.G. - Pelletization by controlled wet granulation in a high-shear mixer. - S.T.P. Pharma Sci., 3, 286-293, 1993.
14. KRISTENSEN H.G. and SCHAEFER T. - Granulations. - In: Encyclopedia of Pharmaceutical Technology, Vol. VII, J. Swarbrick and J.C. Boyland Eds., Marcel Dekker, New York, 1993, pp. 121-160.
15. SCHAEFER T. and WøRTS O. - Control of fluidized bed granulation. I: Effect of spray angle, nozzle height and starting materials on granule size and size distribution. - Arch. Pharm. Chemi. Sci. Ed., 5, 51-60, 1977.