Synthesis and evaluation of some masked phosphate esters of the anti- herpesvirus drug 882C (netivudine) as potential antiviral agents

Antiviral Chemistry and Chemotherapy

Volumn 9, Issue 3, 1998, Pages 233-243

  McGuigan, C ^a   Perry, A ^a   Yarnold, C J ^a   Sutton, P W ^a   Lowe, D ^b   Miller, W ^c   Rahim, S G ^b   Slater, M J ^b  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c GLAXOSMITHKLINE   (United States)

Author keywords

882C; kinase by pass; Netivudine; Nucleoside phosphate esters; Phosphorylation

Indexed keywords

ANTIVIRUS AGENT; DNA POLYMERASE; ESTERASE; NETIVUDINE; NUCLEOSIDE ANALOG; PRODRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HERPES VIRUS INFECTION; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; SPECTROSCOPY;

EID: 0031775623     PISSN: 09563202     EISSN: None     Source Type: Journal    
DOI: 10.1177/095632029800900304     Document Type: Article

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