Heterotrophic production potential of omega-3 polyunsaturated fatty acids by microalgae and algae-like microorganisms

Botanica Marina

Volumn 41, Issue 6, 1998, Pages 553-558

  Vazhappilly, R ^a   Chen, F ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ALGAE; AMPHIDINIUM; AMPHIDINIUM CARTERAE; CRYPTHECODINIUM COHNII; DINOPHYCEAE; EUKARYOTA; SCHIZOCHYTRIUM; SCHIZOCHYTRIUM AGGREGATUM;

EID: 0031775536     PISSN: 00068055     EISSN: None     Source Type: Journal    
DOI: 10.1515/botm.1998.41.1-6.553     Document Type: Article

References (26)

1. Barclay, W. R., K. M. Meager and J. R. Abril. 1994. Heterotrophic production of long chain omega-3 fatty acids utilizing algae and algae-like microorganisms. J. Appl. Phycol. 6: 123-129.
2. Behrens, P. W., S. D. Hoeksema, K. L. Arnett, M. S. Cole, T. A. Heubne, J. M. Rutten and D. J. Kyle. 1989. Eicosapentaenoic acid from microalgae. In: (A. L. Demain, J. A. Somkuti, J. C. Hunter-Cever and H. W. Rossmoore, eds) Novel Microbial Products for Medicine and Agriculture. Elsevier Science Publishers, Amsterdam, 253-259.
3. Bligh, E. G. and W. J. Dyer. 1959. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37: 911-817.
4. Chen, F. 1996. High cell density culture of microalgae in heterotrophic growth. Trends Biotechnol. 14: 421-426.
5. Chen, F. and M. R. Johns. 1991. Effect of C/N ratio and aeration on fatty acid composition of heterotrophic Chlorella sorokiniana. J. Appl. Phycol. 3: 203-209.
6. Chen, F. and M. R. Johns. 1994. Substrate inhibition of Chlamydomonas reinhardtii by acetate in heterotrophic culture. Process Biochem. 29: 245-252.
7. Chen, F. and M. R. Johns. 1996. High cell density culture of Chlamydomonas reinhardtii on acetate using fed-batch and hollow fibre cell recycle systems. Biores. Technol. 55: 103-110.
8. Christie, W. W. 1992. Gas Chromatography and Lipids. A Practical Guide. The Oily Press, Ayr. pp. 29-70.
9. Cohen, Z. 1994. Production potential of eicosapentaenoic acid by Monodus subterraneus. J. Am. Oil. Chem. Soc. 77: 941-945.
10. Conway, E. J. and M. Downey. 1950. An outer metabolic region of the yeast cell. Biochem. J. 47: 347-355.
11. Dervon, C. A., I. Baksaas and H. E. Krokan. 1993. Omega-3 Fatty Acids: Metabolism and Biological Effects. Birkhauser Verlag, Basel, Switzerland, pp. 87-343.
12. Dickson, L. G., R. A. Galloway and G. W. Patterson. 1969. Environmentally induced changes in the fatty acids of Chlorella. Plant Physiol. 44: 1413-1416.
13. Eichenberger, W. 1976. Lipids of Chlamydomonas reinhardii under different growth conditions. Phytochem. 15: 459-463.
14. James, A. T., R. V. Harris, C. Hitchcock, B. J. B. Wood and B. W. Nichols. 1965. Investigation of the biosynthesis and degradation of unsaturated fatty acids in higher plants and photosynthetic bacteria. Fette-Seifen-Anstrichmittel 67: 393-396.
15. Maiorella, B., H. W. Blanch and C. R. Wike. 1983. By product inhibition effects on ethanolic fermentation by Saccharomyces cerevisiae. Biotechnol. Bioengng. 25: 103-121.
16. Nerad, T. A. 1993. American Type Culture Collection, Catalogue of Protists, 18th edn. Rockville, Maryland, USA. pp. 66-75.
17. Nettleton, A. J. 1995. Omega-3 Fatty Acids and Health. Chapman and Hall, New York. pp. 64-328.
18. Nichols, B. W. and R. S. Appleby. 1969. The distribution and biosynthesis of arachidonic acid in algae. Phytochem. 8: 1907-1915.
19. Radwan, S. S. and H. K. Mangold. 1980. Biochemistry of lipids in plant cell cultures. Adv. Biochem. Eng. 16: 109-133.
20. Samson, F. E. 1955. Effects of acetate and other short-chain fatty acids on yeast metabolism. Arch. Biochem. Biophys. 54: 406-423.
21. Simopoulos, A. P., R. R. Kifer, R. E. Martin and S. M. Barlaw. 1991. Health Effects of Omega-3 Polyunsaturated Fatty Acids. S. Karger, Basel, Switzerland, pp. 74-448.
22. Starr, R. C. and J. A. Zeikus. 1993. The culture collection of algae at the University of Texas at Austin. J. Phycol. 29 (suppl.): 1-106.
23. Suen, Y., J. S. Hubbard, G. Holzer and T. G. Tornabene. 1987. Total lipid production of the green alga Nannochloropsis sp. QII under different nitrogen regimes. J. Phycol. 23: 289-296.
24. Tan, C. K. and M. R. Johns. 1996. Screening of diatoms for heterotrophic eicosapentaenoic acid production. J. Appl. Phycol. 8: 59-64.
25. Vazhappilly, R. and F. Chen. 1998. Eicosapentaenoic aicd and docosahexaenoic acid production potential of microalgae and their heterotrophic growth. J. Am. Oil Chem. Soc. 75: 393-397.
26. Yongmanitachai, W. and O. P. Ward. 1989. Omega-3 fatty acids: alternative sources of production. Process Biochem. 24: 117-125.