Defective Kin28, a subunit of yeast TFIIH, impairs transcription-coupled but not global genome nucleotide excision repair

Mutation Research - DNA Repair

Volumn 409, Issue 3, 1998, Pages 181-188

  Tijsterman, Marcel ^a   Tasseron De Jong, Judith G ^a   Verhage, Richard A ^a   Brouwer, Jaap ^a  

^a Dept Molec Genet Leiden Inst C   (Netherlands)

Author keywords

CPD; Kin28; Nucleotide excision repair; Transcription; Transcription coupled repair; Yeast

Indexed keywords

DNA BINDING PROTEIN; PYRIMIDINE DIMER; RNA POLYMERASE II;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; EXCISION REPAIR; IN VITRO STUDY; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; YEAST;

CYCLIN-DEPENDENT KINASES; DNA DAMAGE; DNA REPAIR; FUNGAL PROTEINS; GENES, FUNGAL; PROTEIN-SERINE-THREONINE KINASES; PYRIMIDINE DIMERS; RNA POLYMERASE II; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TATA-BINDING PROTEIN ASSOCIATED FACTORS; TRANSCRIPTION FACTOR TFIID; TRANSCRIPTION FACTOR TFIIH; TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS, TFII; TRANSCRIPTION, GENETIC; ULTRAVIOLET RAYS;

SACCHAROMYCES CEREVISIAE;

EID: 0031775217     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(98)00060-3     Document Type: Article

References (41)

1. Mellon I., Spivak G., Hanawalt P.C. Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene. Cell. 51:1987;241-249.
2. Conaway R.C., Conaway J.W. General initiation factors for RNA polymerase II. Annu. Rev. Biochem. 62:1993;161-190.
3. Aboussekhra A., Biggerstaff M., Shivji M.K., Vilpo J.A., Moncollin V., Podust V.N., Protic M., Hubscher U., Egly J.-M., Wood R.D. Mammalian DNA nucleotide excision repair reconstituted with purified protein components. Cell. 80:1995;859-868.
4. Mu D., Park C.H., Matsunaga T., Hsu D.S., Reardon J.T., Sancar A. Reconstitution of human DNA repair excision nuclease in a highly defined system. J. Biol. Chem. 270:1995;2415-2418.
5. Schaeffer L., Roy R., Humbert S., Moncollin V., Vermeulen W., Hoeijmakers J.H.J., Chambon P., Egly J.-M. DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor. Science. 260:1993;58-63.
6. Feaver W.J., Svejstrup J.Q., Bardwell L., Bardwell A.J., Buratowski S., Gulyas K.D., Donahue T.F., Friedberg E.C., Kornberg R.D. Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair. Cell. 75:1993;1379-1387.
7. Drapkin R., Reardon J.T., Ansari A., Huang J.C., Zawel L., Ahn K., Sancar A., Reinberg D. Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II. Nature. 368:1994;769-772.
8. Buratowski S. DNA repair and transcription: the helicase connection. Science. 260:1993;37-38.
9. Zawel L., Kumar K.P., Reinberg D. Recycling of the general transcription factors during RNA polymerase II transcription. Genes Dev. 9:1995;1479-1490.
10. Goodrich J.A., Tjian R. Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II. Cell. 77:1994;145-156.
11. Gulyas K.D., Donahue T.F. SSL2, a suppressor of a stem-loop mutation in the HIS4 leader encodes the yeast homolog of human ERCC-3. Cell. 69:1992;1031-1042.
12. Sung P., Prakash L., Matson S.W., Prakash S. RAD3 protein of Saccharomyces cerevisiae is a DNA helicase. Proc. Natl. Acad. Sci. USA. 84:1987;8951-8955.
13. Valay J.G., Simon M., Faye G. The kin28 protein kinase is associated with a cyclin in Saccharomyces cerevisiae. J. Mol. Biol. 234:1993;307-310.
14. Feaver W.J., Svejstrup J.Q., Henry N.L., Kornberg R.D. Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK. Cell. 79:1994;1103-1109.
15. Valay J.G., Simon M., Dubois M.F., Bensaude O., Facca C., Faye G. The KIN28 gene is required both for RNA polymerase II mediated transcription and phosphorylation of the Rpb1p CTD. J. Mol. Biol. 249:1995;535-544.
16. Cismowski M.J., Laff G.M., Solomon M.J., Reed S.I. KIN28 encodes a C-terminal domain kinase that controls mRNA transcription in Saccharomyces cerevisiae but lacks cyclin-dependent kinase-activating kinase (CAK) activity. Mol. Cell. Biol. 15:1995;2983-2992.
17. Yoon H., Miller S.P., Pabich E.K., Donahue T.F. SSL1, a suppressor of a HIS4 5′-UTR stem-loop mutation, is essential for translation initiation and affects UV resistance in yeast. Genes Dev. 6:1992;2463-2477.
18. Gileadi O., Feaver W.J., Kornberg R.D. Cloning of a subunit of yeast RNA polymerase II transcription factor b and CTD kinase. Science. 257:1992;1389-1392.
19. Feaver W.J., Henry N.L., Wang Z., Wu X., Svejstrup J.Q., Bushnell D.A., Friedberg E.C., Kornberg R.D. Genes for Tfb2, Tfb3, and Tfb4 subunits of yeast transcription/repair factor IIH. Homology to human cyclin-dependent kinase activating kinase and IIH subunits. J. Biol. Chem. 272:1997;19319-19327.
20. Wang Z., Svejstrup J.Q., Feaver W.J., Wu X., Kornberg R.D., Friedberg E.C. Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast. Nature. 368:1994;74-76.
21. Svejstrup J.Q., Feaver W.J., LaPointe J., Kornberg R.D. RNA polymerase transcription factor IIH holoenzyme from yeast. J. Biol. Chem. 269:1994;28044-28048.
22. Qiu H., Park E., Prakash L., Prakash S. The Saccharomyces cerevisiae DNA repair gene RAD25 is required for transcription by RNA polymerase II. Genes Dev. 11:1993;2161-2171.
23. Guzder S.N., Qiu H., Sommers C.H., Sung P., Prakash L., Prakash S. DNA repair gene RAD3 of S. cerevisiae is essential for transcription by RNA polymerase II. Nature. 367:1994;91-94.
24. Wang Z., Buratowski S., Svejstrup J.Q., Feaver W.J., Wu X., Kornberg R.D., Donahue T.F., Friedberg E.C. The yeast TFB1 and SSL1 genes, which encode subunits of transcription factor IIH, are required for nucleotide excision repair and RNA polymerase II transcription. Mol. Cell. Biol. 15:1995;2288-2293.
25. Sung P., Guzder S.N., Prakash L., Prakash S. Reconstitution of TFIIH and requirement of its DNA helicase subunits, Rad3 and Rad25, in the incision step of nucleotide excision repair. J. Biol. Chem. 271:1996;10821-10826.
26. Roy R., Adamczewski J.P., Seroz T., Vermeulen W., Tassan J.P., Schaeffer L., Nigg E.A., Hoeijmakers J.H.J., Egly J.-M. The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor. Cell. 79:1994;1093-1101.
27. Guzder S.N., Habraken Y., Sung P., Prakash L., Prakash S. Reconstitution of yeast nucleotide excision repair with purified Rad proteins, replication protein A, and transcription factor TFIIH. J. Biol. Chem. 270:1995;12973-12976.
28. Lauder S., Bankmann M., Guzder S.N., Sung P., Prakash L., Prakash S. Dual requirement for the yeast MMS19 gene in DNA repair and RNA polymerase II transcription. Mol. Cell. Biol. 16:1996;6783-6793.
29. Lombaerts M., Tijsterman M., Verhage R.A., Brouwer J. Saccharomyces cerevisiae mms19 mutants are deficient in transcription-coupled and global nucleotide excision repair. Nucleic Acids Res. 25:1997;3974-3979.
30. Verhage R., Zeeman A.M., de Groot N., Gleig F., Bang D.D., van de Putte P., Brouwer J. The RAD7 and RAD16 genes, which are essential for pyrimidine dimer removal from the silent mating type loci, are also required for repair of the nontranscribed strand of an active gene in Saccharomyces cerevisiae. Mol. Cell. Biol. 14:1994;6135-6142.
31. Tijsterman M., Tasseron-de Jong J.G., van de Putte P., Brouwer J. Transcription-coupled and global genome repair in the Saccharomyces cerevisiae RPB2 gene at nucleotide resolution. Nucleic Acids Res. 24:1996;3499-3506.
32. Sweder K.S., Hanawalt P.C. The COOH terminus of suppressor of stem loop (SSL2/RAD25) in yeast is essential for overall genomic excision repair and transcription-coupled repair. J. Biol. Chem. 269:1994;1852-1857.
33. Sweder K.S., Chun R., Mori T., Hanawalt P.C. DNA repair deficiencies associated with mutations in genes encoding subunits of transcription initiation factor TFIIH in yeast. Nucleic Acids Res. 24:1996;1540-1546.
34. Wellinger R.E., Thoma F. Nucleosome structure and positioning modulate nucleotide excision repair in the non-transcribed strand of an active gene. EMBO J. 15:1997;5046-5056.
35. M. Tijsterman, R. de Pril, J.G. Tasseron-de Jong, J. Brouwer, RNA polymerase II transcription suppresses nucleosomal modulation of UV-induced (6-4) photoproduct and cyclobutane pyrimidine dimer repair in yeast, Mol. Cell. Biol., in press.
36. Tanaka S., Livingstone-Zatchej M., Thoma F. Chromatin structure of the yeast URA3 gene at high resolution provides insight into structure and positioning of nucleosomes in the chromosomal context. J. Mol. Biol. 257:1996;919-934.
37. Svejstrup J.Q., Vichi P., Egly J.-M. The multiple roles of transcription/repair factor TFIIH. Trends Biochem. Sci. 21:1996;346-350.
38. Orphanides G., Lagrange T., Reinberg D. The general transcription factors of RNA polymerase II. Genes Dev. 10:1996;2657-2683.
39. Selby C.P., Drapkin R., Reinberg D., Sancar A. RNA polymerase II stalled at a thymine dimer: footprint and effect on excision repair. Nucleic Acids Res. 25:1997;787-793.
40. Aboussekhra A., Thoma F. Nucleotide excision repair and photolyase preferentially repair the nontranscribed strand of RNA polymerase III-transcribed genes in Saccharomyces cerevisiae. Genes Dev. 12:1998;411-421.
41. Livingstone-Zatchej M., Meier A., Suter B., Thoma F. RNA polymerase II transcription inhibits DNA repair by photolyase in the transcribed strand of active yeast genes. Nucleic Acids Res. 25:1997;3795-3800.