Growth hormone (GH) response to GH-releasing peptide-6 in type 1 diabetic patients with exaggerated GH-releasing hormone-stimulated GH secretion

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 10, 1998, Pages 3663-3667

  Catalina, Pablo F ^a   Mallo, Federico ^c   Andrade, M Amelia ^b   García Mayor, Ricardo V ^b   Diéguez, Carlos ^d  

^a HOSPITAL MONTECELO   (Spain)

^b HOSPITAL XERAL CÍES   (Spain)

^c UNIVERSITY OF VIGO   (Spain)

^d UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE RELEASING FACTOR;

ADULT; ARTICLE; BODY MASS; CLINICAL ARTICLE; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; FEEDBACK SYSTEM; GLUCOSE BLOOD LEVEL; GROWTH HORMONE RELEASE; HORMONE RESPONSE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MALE; METABOLIC REGULATION; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; STIMULUS RESPONSE;

ADULT; DIABETES MELLITUS, TYPE 1; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; GROWTH HORMONE-RELEASING HORMONE; HUMAN GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; OLIGOPEPTIDES; REFERENCE VALUES;

EID: 0031774362     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.83.10.3663     Document Type: Article

References (34)

1. Hansen AP, Johansen K. 1970 Diurnal patterns of blood glucose, serum free fatty acids, insulin, glucagon and growth hormone in normals and juvenile diabetics. Diabetologia. 6:27-33.
2. Hansen AP. 1970 Abnormal serum growth hormone response to exercise in juvenile diabetics. J Clin Invest. 49:1467-1478.
3. Speroni G, Ceda GP, Capretti L, Valenti G. 1983 Clonidine and GH secretion in insulin dependent diabetes (IDD). Horm Metab Res. 15:46-47.
4. Burday SZ, Fine PH, Schalch DS. 1968 Growth hormone secretion in response to arginine infusion in normal and diabetic subjects: relationship to blood glucose levels. J Lab Clin Med. 71:897-911.
5. Ajlouni K, Martinson DR, Hagen TC. 1975 Effect of glucose on the growth hormone response to L-dopa in normal and diabetic subjects. Diabetes. 24:633-636.
6. Lorenzi M, Karam JH, McIlroy MB, Forsham PH. 1980 Increased growth hormone response to dopamine infusion in insulin-dependent diabetic subjects. J Clin Invest. 65:146-153.
7. Krassowski J, Felber JP, Rogala H, Jeske W, Zgliczynski S. 1988 Exaggerated growth hormone response to growth hormone-releasing hormone in type I diabetes mellitus. Acta Endocrinol (Copenh). 117:225-229.
8. Edge JA, Dunger DB, Matthews DR, Gilbert JP, Smith CP. 1990 Increased overnight growth hormone concentrations in diabetic compared with normal adolescents. J Clin Endocrinol Metab. 71:1356-1362.
9. Asplin CM, Faria ACS, Carlsen EC, et al. 1989 Alterations in the pulsatile mode of growth hormone release in men and women with insulin-dependent diabetes mellitus. J Clin Endocrinol Metab. 69:239-245.
10. Villas-Boas RF, Ramos-Dias JC, Chipoch C, Lengyel AMJ. 1997 Growth hormone (GH) response to GH-releasing peptide-6 in patients with insulin-dependent diabetes mellitus. Metabolism. 46:706-710.
11. Micic D, Mallo F, Peinó R, et al. 1993 Regulation of growth hormone secretion by the growth hormone releasing hexapeptide (GHRP-6). J Pediatr Endocrinol. 6:283-289.
12. Peñalva A, Carballo A, Pombo M, Casanueva FF, Diéguez C. 1993 Effect of growth hormone (GH)-releasing hormone (GHRH), atropine, pyridostigmine, or hypoglycemia on GHRP-6 induced GH secretion in man. J Clin Endocrinol Metab. 76:168-171.
13. Ghigo E, Arvat E, Muccioli G, Camanni F. 1997 Growth hormone-releasing peptides. Eur J Endocrinol. 136:445-460.
14. Press M, Tamborlane WV, Thomer MO, et al. 1984 Pituitary response to growth hormone-releasing factor in diabetes. Failure of glucose-mediated suppression. Diabetes. 33:804-806.
15. Horner JM, Kemp SF, Hintz RL. 1981 Growth hormone and somatomedin in insulin-dependent diabetes mellitus. J Clin Endocrinol Metab. 53:1148-1153.
16. Alzaid AA, Melton LJ, Dinneen SF, Rizza RA. 1994 The role of growth hormone in the development of diabetic retinopathy. Diabetes Care. 17:531-534.
17. Sharp PS. 1995 The role of growth factors in the development of diabetic retinopathy. Metabolism. [Suppl 4]44:72-75.
18. Feld S, Hirschberg R. 1996 Growth hormone, the insulin-like growth factor system and the kidney. Endocr Rev. 17:423-480.
19. Muchaneta-Kubara EC, Sayed-Ahmed N, Besbas N, Zhang G, Cope GH, El Nahas AM. 1994 Experimental diabetic renal growth: role of growth hormone and insulin-like growth factor I. Nephrol Dial Transplant. 9:1395-1401.
20. Houssay BA, Magenta MA. 1924 Sensibilidad en los perros hipofisoprivos a 1a insulina. Rev Asoc Med Arg (Soc Biol). 37:389-406.
21. Lyall A, Innes JA. 1935 Diabetes mellitus and the pituitary gland. A case of diabetes with intercurrent pituitary lesion and concomitant improvement of diabetes. Lancet. 1:318-321.
22. Press M, Tamborlane WV, Sherwin RS. 1984 Importance of raised growth hormone levels in mediating the metabolic derangements of diabetes. N Engl J Med. 310:810-815.
23. Merimee TJ, Fitzgerald CR, Gold LA, McCourt JP. 1979 Characteristics of growth hormone secretion in clinically stable diabetes. Diabetes. 28:308-312.
24. Hayford JT, Danney MM, Hendrix JA, Thompson RG. 1980 Integrated concentration of growth hormone in juvenile-onset diabetes. Diabetes. 29:391-398.
25. Schaper NC, Verhoeff AJ, Sluiter WJ, Roelse H, Reitsma WD, Doorenbos H. 1990 The growth hormone response to growth hormone-releasing hormone and its relationship to serum insulin-like growth factor I in type I diabetes mellitus. Acta Endocrinol (Copenh). 122:13-18.
26. Kopelman PG, Mason AC, Noonan K, Monson JP. 1988 Growth hormone response to growth hormone releasing factor in diabetic men. Clin Endocrinol (Oxf). 28:33-38.
27. Cordido F, Peñalva A, Diéguez C, Casanueva FF. 1993 Massive growth hormone (GH) discharge in obese subjects after the combined administration of GH-releasing hormone and GHRP-6:evidence for a marked somatotroph secretory capability in obesity. J Clin Endocrinol Metab. 76:819-823.
28. Popovic V, Damjanovic S, Micic D, Petakov M, Diéguez C, Casanueva FF. 1994 Growth hormone (GH) secretion in active acromegaly after the combined administration of GH-releasing hormone and GH-releasing peptide. J Clin Endocrinol Metab. 79:456-460.
29. Leal-Cerro A, Pumar A, García E, Diéguez C, Casanueva FF. 1994 Inhibition of growth hormone release after the combined administration of GHRH and GHRP-6 in patients with Cushing's syndrome. Clin Endocrinol (Oxf). 41:649-654.
30. Pombo M, Barreiro J, Peñalva A, Mallo F, Casanueva FF, Diéguez C. 1995 Plasma growth hormone response to growth hormone releasing hexapeptide (GHRP-6) in children with short stature. Acta Paediatr. 84:904-908.
31. Micic D, Kendereski A, Popovic V, et al. 1996 Growth hormone response to GHRH, GHRP-6 and GHRH + GHRP-6 in patients with polycystic ovary syndrome. Clin Endocrinol (Oxf). 45:385-390.
32. Howard AD, Feighner SD, Cully DF et al. 1996 A receptor in pituitary and hypothalamus that functions in growth hormone release. Science. 273:974-977.
33. Popovic V, Damjanovic S, Micic D, Djurovic M, Diéguez C, Casanueva FF. 1995 Blocked growth hormone-releasing peptide (GHRP-6)-induced GH secretion and absence of the synergic action of GHRP-6 plus GH-releasing hormone in patients with hypothalamopituitary disconnection: evidence that GHRP-6 main action is exerted at the hypothalamic level. J Clin Endocrinol Metab. 80:942-947.
34. Maccario M, Arvat E, Procopio M, et al. 1995 Metabolic modulation of the growth hormone-releasing activity of hexarelin in man. Metabolism. 44:134-138.