Organization of splicing factors in adenovirus-lnfected cells reflects changes in gene expression during the early to late phase transition

Experimental Cell Research

Volumn 245, Issue 1, 1998, Pages 203-213

  Aspegren, Anders ^a   Rabino, Claudia ^a   Bridge, Eileen ^a,b  

^a UPPSALA UNIVERSITY   (Sweden)

^b MIAMI UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS; ARTICLE; CHROMATIN; CONTROLLED STUDY; DNA DETERMINATION; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; VIRUS DETECTION; VIRUS INFECTION; VIRUS TRANSCRIPTION;

ADENOVIRIDAE;

EID: 0031773202     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1998.4264     Document Type: Article

References (46)

1. Bridge, E., and Pettersson, U. (1995). Nuclear organization of replication and gene expression in adenovirus-infected cells. Curr. Top. Microbial. Immunol. 199(Pt. 1), 99-117.
2. Bridge, E., and Pettersson, U. (1996). Nuclear organization of adenovirus RNA biogenesis. Exp. Cell Res. 229, 233-239.
3. Krug, R. M. (1993). The regulation of export of mRNA from nucleus to cytoplasm. Curr. Opin. Cell. Biol. 5, 944-949.
4. Jackson, D. A., Hassan, A. B., Errington, R. J., and Cook, P. R. (1993). Visualization of focal sites of transcription within human nuclei. EMBO J. 12, 1059-1065.
5. Wansink, D. G., Schul, W., van der Kraan, I., van Steensel, B., van Driel, R., and de Jong, L. (1993). Fluorescent labelling of nascent RNA reveals transcription by RNA polymerase II in domains scattered throughout the nucleus. J. Cell Biol. 122, 283-293.
6. Pombo, A., Ferreira, J., Bridge, E., and Carmo-Fonseca, M. (1994). Adenovirus replication and transcription sites are spatially separated in the nucleus of infected cells. EMBO J. 13, 5075-5085.
7. Puvion-Dutilleul, F., Roussev, R., and Puvion, E. (1992). Distribution of viral RNA molecules during the adenovirus type 5 infectious cycle in HeLa cells. J. Struct. Biol. 108, 209-220.
8. Zhang, G., Taneja, K. L., Singer, R. H., and Green, M. R. (1994). Localization of pre-mRNA splicing in mammalian nuclei. Nature 372, 809-812.
9. Singer, R. H., and Green, M. R. (1997). Compartmentalization of eukaryotic gene expression: Causes and effects. Cell 91, 291-294.
10. Beyer, A. L., and Osheim, Y. N. (1988). Splice site selection, rate of splicing, and alternative splicing on nascent transcripts. Genes Dev. 2, 754-765.
11. Baurén, G., and Wieslander, L. (1994). Splicing of Balbiani ring 1 gene pre-mRNA occurs simultaneously with transcription. Cell 76, 183-192.
12. Gama-Carvalho, M., Krauss, R. D., Chiang, L., Valcarcel, J., Green, M. R., and Carmo-Fonseca, M. (1997). Targeting of U2AF65 to sites of active splicing in the nucleus. J. Cell Biol. 137, 975-987.
13. Huang, S., and Spector, D. L. (1996). Intron dependent recruitment of pre-mRNA splicing factors to sites of transcription. J. Cell Biol. 133, 719-732.
14. Zeng, C., Kim, E., Warren, S. L., and Berget, S. M. (1997). Dynamic relocation of transcription and splicing dependent upon transcriptional activity. EMBO J. 16, 1401-1412.
15. + Nuclear sequences are conserved and poly(A) addition precedes splicing. Cell 15, 1477-1493.
16. Nevins, J. R. (1983). The pathway of eukaryotic mRNA formation. Annu. Rev. Biochem. 52, 441-446.
17. Izaurralde, E., and Mattaj, I. W. (1995). RNA export. Cell 81, 153-159.
18. Nigg, E. A. (1997). Nucleocytoplasmic transport: Signals, mechanisms and regulation. Nature 386, 779-787.
19. Fischer, U., Michael, W. M., Lührmann, R., and Dreyfuss, G. (1996). Signal-mediated nuclear export pathways of proteins and RNAs. Trends Cell Biol. 6, 290-293.
20. Nakielny, S., and Dreyfuss, G. (1997). Nuclear export of proteins and RNAs. Curr. Opin. Cell. Biol. 9, 420-429.
21. Dobbelstein, M., Roth, J., Kimberly, W. T., Levine, A. J., and Shenk, T. (1997). Nuclear export of the E1b 55-kDa and E4 34-kDa adenoviral oncoproteins mediated by a Rev-like signal sequence. EMBO J. 16, 4276-4284.
22. Cutt, J. R., Shenk, T., and Hearing, P. (1987). Analysis of adenovirus early region 4-encoded polypeptides synthesized in productively infected cells. J. Virol. 61, 543-552.
23. Pilder, S., Moore, M., Logan, J., and Shenk, T. (1986). The adenovirus E1B-55K transforming polypeptide modulates transport of cytoplasmic stabilization of viral and host cell mRNAs. Mol. Cell Biol. 6, 470-476.
24. Daneholt, B. (1997). A look at messenger RNP moving through the nuclear pore. Cell 88, 585-588.
25. Visa, N., Alzhanova-Ericsson, A. T., Sun, X., Kiseleva, E., Bjorkroth, B., Wurtz, T., and Daneholt, B. (1996). A pre-mRNA-binding protein accompanies the RNA from the gene through the nuclear pores and into polysomes. Cell 84, 253-264.
26. Alzhanova-Ericsson, A. T., Sun, X., Visa, N., Kiseleva, E., Wurtz, T., and Daneholt, B. (1996). A protein of the SR family of splicing factors binds extensively to exonic Balbiani ring pre-mRNA and accompanies the RNA from the gene to the nuclear pore. Genes Dev. 10, 2881-2893.
27. Visa, N., Izaurralde, E., Ferreira, J., Daneholt, B., and Mattaj, I. W. (1996). A nuclear Cap-binding complex binds balbiani ring pe-mRNA cotranscriptionally and accompanies the ribonucleo-proteins particle during nuclear export. J. Cell Biol. 133, 5-14.
28. Bridge, E., Carmo-Fonseca, M., Lamond, A. I., and Pettersson, U. (1993). Nuclear organization of splicing small nuclear ribonucleo-proteins in adenovirus-infected cells. J. Virol. 67, 5792-5802.
29. Bridge, E., Xia, D.-X., Carmo-Fonseca, M., Cardinali, B., Lamond, A. I., and Pettersson, U. (1995). Dynamic organization of splicing factors in adenovirus-infected cells. J. Virol. 69, 281-290.
30. Bridge, E., Riedel, K.-U., Johansson, B.-M., and Pettersson, U. (1996). Spliced exons of adenovirus late RNAs colocalize with snRNP in a specific nuclear domain. J. Cell Biol. 135, 303-314.
31. Huang, S., and Spector, D. L. (1996). Dynamic organization of pre-mRNA splicing factors. J. Cell. Biochem. 62, 191-197.
32. Puvion-Dutilleul, F., Bachellerie, J.-P., Visa, N., and Puvion, E. (1994). Rearrangements of intranuclear structures involved in RNA processing in response to adenovirus infection. J. Cell Sci. 107, 1457-1468.
33. Philipson, L. (1961). Adenovirus assay by the fluorescent cell counting procedure. Virology 15, 263-268.
34. Lerner, E. A., Lerner, M. R., Janeway, C. A., and Steitz, J. A. (1981). Monoclonal antibodies to nucleic acid-containing cellular constituents: Probes for molecular biology and autoimmune disease. Proc. Natl. Acad. Sci. USA 78, 2737-2741.
35. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989). In "Molecular Cloning: A Laboratory Manual," 2nd ed., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
36. Besse, S., Diaz, J. J., Pichard, E., Kindbeiter, K., Madjar, J. J., and Puvion-Dutilleul, F. (1996). In situ hybridization and immuno-electron microscope analyses of the Us11 gene of herpes simplex virus type 1 during transient expression. Chromosoma 104, 434-444.
37. Besse, S., Vigneron, M., Pichard, E., and Puvion-Dutilleul, F. (1995). Synthesis and maturation of viral transcripts in herpes simplex virus type 1 infected HeLa cells: the role of interchromatin granules. Gene Expression 4, 143-161.
38. Berthold, E., and Maldarelli, F. (1996). cis-acting elements in human immunodeficiency virus type 1 RNAs direct viral transcripts to distinct intranuclear locations. J. Virol. 70, 4667-4682.
39. Xing, Y., Johnson, C. V., Dobner, P. R., and Lawrence, J. B. (1993). Higher level organization of individual gene transcription and RNA splicing. Science 259, 1326-1329.
40. Xing, Y., Johnson, C. V., Moen, P. T. Jr., McNeil, J. A., and Lawrence, J. B. (1995). Nonrandom gene organization: Structural arrangements of specific pre-mRNA transcription and splicing with SC-35 domains. J. Cell Biol. 131, 1635-1647.
41. Schul, W., van Driel, R., and de Jong, L. A. (1998). A subset of poly(A) polymerase is concentrated at sites of RNA synthesis and is associated with domains enriched in splicing factors and poly(A) RNA. Exp. Cell Res. 238, 1-12.
42. Misteli, T., and Spector, D. L. (1997). Protein phosphorylation and the nuclear organization of pre-mRNA splicing. Trends Cell Biol. 7, 135-137.
43. Caceres, J. F., Screaton, G. R., and Krainer, A. R. (1998). A specific subset of SR proteins shuttles continuously between the nucleus and the cytoplasm. Genes Dev. 12, 55-66.
44. Misteli, T., and Spector, D. L. (1996). Serine/threonine phosphatase 1 modulates the subnuclear distribution of pre-mRNA splicing factors. Mol. Biol. Cell 7, 1559-1572.
45. van Oostrum, J., and Burnett, R. M. (1985). Molecular composition of the adenovirus type 2 virion. J. Virol. 56, 439-448.
46. Pettersson, U. (1983). Structural and nonstructural adenovirus proteins. In "The Adenoviruses" (H. Ginsberg, Ed.), pp. 205-270, Plenum, New York.