메뉴 건너뛰기




Volumn 42, Issue 4, 1998, Pages 775-779

NLCQ-1, a novel hypoxic cytotoxin: Potentiation of melphalan, cisDDP and cyclophosphamide in vivo

Author keywords

Bioreductive drugs; Chemotherapeutic agents; NLCQ 1; Potentiation

Indexed keywords

4 [3 (2 NITROIMIDAZOLYL)PROPYLAMINO] 7 CHLOROQUINOLINE; CISPLATIN; CYCLOPHOSPHAMIDE; CYTOTOXIN; MELPHALAN; NITROIMIDAZOLE DERIVATIVE; TIRAPAZAMINE; UNCLASSIFIED DRUG;

EID: 0031773145     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(98)00333-2     Document Type: Conference Paper
Times cited : (25)

References (27)
  • 2
    • 0027339592 scopus 로고
    • 2 predicts survival in advanced cancer of the uterine cervix
    • 2 predicts survival in advanced cancer of the uterine cervix. Radiother Oncol. 26:1993;45-50.
    • (1993) Radiother Oncol , vol.26 , pp. 45-50
    • Hockel, M.1    Knoop, C.2    Schlenger, K.3
  • 3
    • 0021216039 scopus 로고
    • Modification of chemotherapy by nitroimidazoles
    • Siemann D.W. Modification of chemotherapy by nitroimidazoles. Int J Radiat Oncol Biol Phys. 10:1984;1585-1594.
    • (1984) Int J Radiat Oncol Biol Phys , vol.10 , pp. 1585-1594
    • Siemann, D.W.1
  • 4
    • 0024207211 scopus 로고
    • Effect of cancer chemotherapy on the hypoxic fraction of a solid tumor measured using a local tumor control assay
    • Grau C., Overgaard J. Effect of cancer chemotherapy on the hypoxic fraction of a solid tumor measured using a local tumor control assay. Radiother Oncol. 13:1988;301-309.
    • (1988) Radiother Oncol , vol.13 , pp. 301-309
    • Grau, C.1    Overgaard, J.2
  • 5
    • 0023555121 scopus 로고
    • Hypoxic cells as specific drug targets for chemotherapy
    • Kennedy K.A. Hypoxic cells as specific drug targets for chemotherapy. Anticancer Drug Des. 2:1987;181-194.
    • (1987) Anticancer Drug des , vol.2 , pp. 181-194
    • Kennedy, K.A.1
  • 6
    • 0023902264 scopus 로고
    • Therapeutic attack of hypoxic cells of solid tumors: Presidential address
    • Sartorelli A.C. Therapeutic attack of hypoxic cells of solid tumors presidential address . Cancer Res. 48:1988;775-778.
    • (1988) Cancer Res , vol.48 , pp. 775-778
    • Sartorelli, A.C.1
  • 7
    • 0026792835 scopus 로고
    • Potentiation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea's toxicity in vitro by two new bioreductive agents
    • Papadopoulou M.V., Mainwaring A., Bloomer W.D. Potentiation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea's toxicity in vitro by two new bioreductive agents. Jpn J Cancer Res. 83:1992;907-913.
    • (1992) Jpn J Cancer Res , vol.83 , pp. 907-913
    • Papadopoulou, M.V.1    Mainwaring, A.2    Bloomer, W.D.3
  • 8
    • 84982712502 scopus 로고
    • Potentiation of antineoplastic drugs in vitro and in vivo by intercalating bioreductive agents
    • Papadopoulou M.V., Miller A., Seskey T., et al. Potentiation of antineoplastic drugs in vitro and in vivo by intercalating bioreductive agents. Radiat Oncol Invest. 1:1993;206-217.
    • (1993) Radiat Oncol Invest , vol.1 , pp. 206-217
    • Papadopoulou, M.V.1    Miller, A.2    Seskey, T.3
  • 9
    • 0029938276 scopus 로고    scopus 로고
    • THNLA-1: A DNA-targeted bioreductive agent as chemosensitizer in vitro and in vivo
    • Papadopoulou M.V., Ji M., Bloomer W.D. THNLA-1 A DNA-targeted bioreductive agent as chemosensitizer in vitro and in vivo . In Vivo. 10:1996;49-58.
    • (1996) In Vivo , vol.10 , pp. 49-58
    • Papadopoulou, M.V.1    Ji, M.2    Bloomer, W.D.3
  • 10
    • 0029993225 scopus 로고    scopus 로고
    • THNLA-1 as radio/chemosensitizer of EMT6 tumors in mice
    • Papadopoulou M.V., Ji M., Bloomer W.D. THNLA-1 as radio/chemosensitizer of EMT6 tumors in mice. Br J Cancer. 74:(Suppl. XXVII):1996;S267-S270.
    • (1996) Br J Cancer , vol.74 , Issue.SUPPL. XXVII
    • Papadopoulou, M.V.1    Ji, M.2    Bloomer, W.D.3
  • 11
    • 0030633994 scopus 로고    scopus 로고
    • 9-[3-(2-Nitro-1-imidazolyl)propylamino]-cyclopenteno[b]quinoline hydrochloride (NLCPQ-1): A novel DNA-affinic bioreductive agent as chemosensitizer I
    • Papadopoulou M.V., Ji M., Rao M.K., Bloomer W.D. 9-[3-(2-Nitro-1-imidazolyl)propylamino]-cyclopenteno[b]quinoline hydrochloride (NLCPQ-1) A novel DNA-affinic bioreductive agent as chemosensitizer I . Oncol Res. 9:1997;249-257.
    • (1997) Oncol Res , vol.9 , pp. 249-257
    • Papadopoulou, M.V.1    Ji, M.2    Rao, M.K.3    Bloomer, W.D.4
  • 12
    • 0020665635 scopus 로고
    • Enhancement of the DNA cross-linking activity of melphalan by misonidazole in vivo
    • Murray D., Meyn R.E. Enhancement of the DNA cross-linking activity of melphalan by misonidazole in vivo. Br J Cancer. 47:1983;195-203.
    • (1983) Br J Cancer , vol.47 , pp. 195-203
    • Murray, D.1    Meyn, R.E.2
  • 13
    • 0026513038 scopus 로고
    • Enhancement of alkylating agent activity by SR-4233 in FSaIIC Murine Fibrosarcoma
    • Holden S.A., Teicher B.A., Ara G., et al. Enhancement of alkylating agent activity by SR-4233 in FSaIIC Murine Fibrosarcoma. J Nat Cancer Inst. 84:1992;187-193.
    • (1992) J Nat Cancer Inst , vol.84 , pp. 187-193
    • Holden, S.A.1    Teicher, B.A.2    Ara, G.3
  • 14
    • 84965808588 scopus 로고
    • Tumor-specific, schedule-dependent interaction between Tirapazamine (SR4233) and Cisplatin
    • Dorie M.J., Brown J.M. Tumor-specific, schedule-dependent interaction between Tirapazamine (SR4233) and Cisplatin. Cancer Res. 53:1993;4633-4636.
    • (1993) Cancer Res , vol.53 , pp. 4633-4636
    • Dorie, M.J.1    Brown, J.M.2
  • 15
    • 0022588325 scopus 로고
    • Sensitization of cancer chemotherapeutic agents by nitroheterocyclics
    • Siemann D.W., Mulcahy R.T. Sensitization of cancer chemotherapeutic agents by nitroheterocyclics. Biochem Pharmacol. 35:1986;111-115.
    • (1986) Biochem Pharmacol , vol.35 , pp. 111-115
    • Siemann, D.W.1    Mulcahy, R.T.2
  • 16
    • 0026758591 scopus 로고
    • Potentiation of alkylating chemotherapy by dual function nitrofurans in multicell spheroids and solid tumors
    • Siemann D.W., Sutherland R.M. Potentiation of alkylating chemotherapy by dual function nitrofurans in multicell spheroids and solid tumors. Radiother Oncol. 24:1992;239-245.
    • (1992) Radiother Oncol , vol.24 , pp. 239-245
    • Siemann, D.W.1    Sutherland, R.M.2
  • 17
    • 0028555808 scopus 로고
    • 9-[3-(2-Nitro-1-imidazolyl)-propylamino]-1,2,3,4-tetrahydroacridine hydrochloride: A novel DNA-affinic hypoxic cell cytotoxin and radiosensitizer. Comparison with NLA-1
    • Papadopoulou M.V., Rosenzweig H.S., Doddi M., Bloomer W.D. 9-[3-(2-Nitro-1-imidazolyl)-propylamino]-1,2,3,4-tetrahydroacridine hydrochloride A novel DNA-affinic hypoxic cell cytotoxin and radiosensitizer. Comparison with NLA-1 . Oncol Res. 6:1994;439-448.
    • (1994) Oncol Res , vol.6 , pp. 439-448
    • Papadopoulou, M.V.1    Rosenzweig, H.S.2    Doddi, M.3    Bloomer, W.D.4
  • 18
    • 0030426530 scopus 로고    scopus 로고
    • 9-[3-(2-Nitro-1-imidazolyl)propylamino]-cyclopenteno[b]quinoline hydrochloride (NLCPQ-1): A novel DNA-affinic bioreductive agent as cytotoxin and radiosensitizer
    • Papadopoulou M.V., Ji M., Doddi M., Bloomer W.D. 9-[3-(2-Nitro-1-imidazolyl)propylamino]-cyclopenteno[b]quinoline hydrochloride (NLCPQ-1) A novel DNA-affinic bioreductive agent as cytotoxin and radiosensitizer . Oncol Res. 8:1996;425-434.
    • (1996) Oncol Res , vol.8 , pp. 425-434
    • Papadopoulou, M.V.1    Ji, M.2    Doddi, M.3    Bloomer, W.D.4
  • 19
    • 0028261377 scopus 로고
    • Hypoxia-selective antitumor agents. 8. Bis(nitroimidazolyl)alkanecarboxamides: A new class of hypoxia-selective cytotoxins and hypoxic cell radiosensitisers
    • Hay M.P., Wilson W.R., Moselen J.W., et al. Hypoxia-selective antitumor agents. 8. Bis(nitroimidazolyl)alkanecarboxamides A new class of hypoxia-selective cytotoxins and hypoxic cell radiosensitisers . J Med Chem. 37:1994;381-391.
    • (1994) J Med Chem , vol.37 , pp. 381-391
    • Hay, M.P.1    Wilson, W.R.2    Moselen, J.W.3
  • 22
    • 0015391488 scopus 로고
    • Characteristics of a serially transplanted mouse mammary tumor and its tissue-culture-adapted derivative
    • Rockwell S.C., Kallman R.F., Fajardo L.F. Characteristics of a serially transplanted mouse mammary tumor and its tissue-culture-adapted derivative. J Natl Cancer Inst. 49:1972;735-749.
    • (1972) J Natl Cancer Inst , vol.49 , pp. 735-749
    • Rockwell, S.C.1    Kallman, R.F.2    Fajardo, L.F.3
  • 23
    • 0021324649 scopus 로고
    • Perfluorochemical emulsions can increase tumor radiosensitivity
    • Teicher B.A., Rose C.M. Perfluorochemical emulsions can increase tumor radiosensitivity. Science. 223:1984;934-936.
    • (1984) Science , vol.223 , pp. 934-936
    • Teicher, B.A.1    Rose, C.M.2
  • 24
    • 0025273627 scopus 로고
    • Addition of 2-nitroimidazole radiosensitizers to cis-diamminedichloro-platinum (II) with radiation and with or without hyperthermia in the murine FSaIIC fibrosarcoma
    • Herman T.S., Teicher B.A., Holden S.A., et al. Addition of 2-nitroimidazole radiosensitizers to cis-diamminedichloro-platinum (II) with radiation and with or without hyperthermia in the murine FSaIIC fibrosarcoma. Cancer Res. 50:1990;2734-2740.
    • (1990) Cancer Res , vol.50 , pp. 2734-2740
    • Herman, T.S.1    Teicher, B.A.2    Holden, S.A.3
  • 26
    • 0031616118 scopus 로고    scopus 로고
    • 9-[3-(2-Nitro-1-imidazolyl)-propylamino]-cyclopenteno[b]quinoline hydrochloride (NLCPQ-1): A novel DNA-affinic bioreductive agent as chemosensitizer: Mechanistic studies. II
    • Papadopoulou M.V., Ji M., Rao M.K., et al. 9-[3-(2-Nitro-1-imidazolyl)-propylamino]-cyclopenteno[b]quinoline hydrochloride (NLCPQ-1) A novel DNA-affinic bioreductive agent as chemosensitizer: Mechanistic studies. II . Oncol Res. 10:1998;163-173.
    • (1998) Oncol Res , vol.10 , pp. 163-173
    • Papadopoulou, M.V.1    Ji, M.2    Rao, M.K.3
  • 27
    • 0011233135 scopus 로고    scopus 로고
    • Mechanistic studies regarding the potentiation of melphalan by the bioreductive compound THNLA-1 in vitro
    • April 20-24, 1996. Washington, DC.
    • Papadopoulou MV, Ji M, Rao MK; et al. Mechanistic studies regarding the potentiation of melphalan by the bioreductive compound THNLA-1 in vitro. Proceedings of the 87th AACR Annual Meeting, April 20-24, 1996. Washington, DC. 1996;37:355-356.
    • (1996) Proceedings of the 87th AACR Annual Meeting , vol.37 , pp. 355-356
    • Papadopoulou, M.V.1    Ji, M.2    Rao, M.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.