A higher frequency of a low activity-related allele of the MAO-A gene in females with obsessive-compulsive disorder

Psychiatric Genetics

Volumn 8, Issue 4, 1998, Pages 255-257

  Camarena, B ^a   Cruz, C ^a   De La Fuente, J R ^b   Nicolini, H ^a  

^a INSTITUTO NACIONAL DE PSIQUIATRÍA RAMÓN DE LA FUENTE MUÑIZ   (Mexico)

^b SECRETARÍA DE SALUD   (Mexico)

Author keywords

Association study; MAO A gene; Obsessive compulsive disorder

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A;

ALLELE; ARTICLE; CLINICAL ARTICLE; COMPULSION; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; HUMAN; MALE; OBSESSION; PRIORITY JOURNAL;

EID: 0031772482     PISSN: 09558829     EISSN: None     Source Type: Journal    
DOI: 10.1097/00041444-199808040-00010     Document Type: Article

References (13)

1. Bach AWJ, Lan NC, Johnson DL, Abell CW, Bembenek ME, Kwan S-W et al. (1988). cDNA cloning of human liver monoamine oxidase A and B: molecular basis of differences in enzymatic properties. Proc Natl Acad Sci USA 85:4934-4938.
2. Caraveo J, González C, Ramos L (1991). Concurrent validity of the DIS experience with psychiatric patients in Mexico City. Hispanic J Behav Sci 13:63-67.
3. Craddock N, Daniels J, Roberts E, Rees M, McGuffin P, Owen MJ (1995). No evidence for allelic association between bipolar disorder and monoamine oxidase A gene polymorphisms. Am J Med Genet 60:322-324.
4. Goodman WK, McDougle CJ, Price LH, Riddle MA, Pauls DL, Leckman JF (1990). Beyond the serotonin hypothesis: a role for dopamine in some forms of obsessive-compulsive disorder? J Clin Psychiatry 51:36-43.
5. Grimsby J, Chen K, Wang LJ, Lan NC, Shih JC (1991). Human monoamine oxidase A and B exhibit identical exon-intron organization. Proc Natl Acad Sci USA 88:3637-3641.
6. Hotamisligil GS, Breakefield XO (1991). Human monoamine oxidase A gene determines levels of enzyme activity. Am J Hum Genet 49:383-392.
7. Karayiorgou M, Altemus M, Galke BL, Goldman D, Murphy DL, Ott J, Gogos JA (1997). Genotype determining low catchecol-o-methyltransferase activity as a risk factor for obsessive-compulsive disorder. Proc Natl Acad Sci USA 94:4572-4575.
8. Lensi P, Cassano GB, Correddu G, Ravagli S, Kunovac JL, Akiskal HS (1996). Obsessive-compulsive disorder. Familial developmental history, symptomatology, comorbidity and course with special reference to gender-related differences. Br J Psychiatry 169:101-107.
9. Lim LCC, Powell J, Sham P, Castle D, Hunt N, Murray R, Gill M (1995). Evidence for genetic association between alleles of monoamine oxidase A gene and bipolar affective disorder. Am J Med Genet 60:325-331.
10. Nicolini H, Cruz C, Camarena B, Orozco B, Kennedy JL, King N et al. (1996). DRD2, DRD3 and 5HT2A receptor genes polymorphisms in obsessive-compulsive disorder. Mol Psychiatry 1:461-465.
11. Noshirvani HF, Kasvikis Y, Marks IM, Tsakiris F, Monteiro WO (1991). Gender-divergent aetiological factors in obsessive-compulsive disorder. Br J Psychiatry 158:260-263.
12. Sasson Y, Zohar J (1996). New developments in obsessive-compulsive disorder research: implications for clinical management. Int Clin Psychopharmacol 11:3-12.
13. Thorpe LW, Westlund KN, Kochersperger LM, Abe CW, Denney RM (1987). Immunocytochemical localization of monoamine oxidase A and B in human peripheral tissues and brain. J Histochem Cytochem 35:23-32.