Rifaximin: A nonabsorbed antimicrobial in the therapy of travelers' diarrhea

Digestion

Volumn 59, Issue 6, 1998, Pages 708-714

  DuPont, H L ^a,b   Ericsson, C D ^b   Mathewson, J J ^b   Palazzini, E ^c   DuPont, M W ^b   Jiang, Z D ^b   Mosavi, A ^b   De La Cabada, F J ^d  

^a ST LUKE S EPISCOPAL HOSPITAL   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c Alfa Wassermann SpA   (Italy)

^d HOSPITAL GENERAL DE OCCIDENTE   (Mexico)

Author keywords

Diarrhea; Rifaximin; Travelers

Indexed keywords

COTRIMOXAZOLE; RIFAXIMIN; SULFONAMIDE; TUBERCULOSTATIC AGENT;

ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; HUMAN; MAJOR CLINICAL STUDY; MEXICO; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; TRAVELLER DIARRHEA; TREATMENT FAILURE;

ACUTE DISEASE; ADOLESCENT; ADULT; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; DIARRHEA; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HUMANS; INTESTINAL ABSORPTION; MALE; PROSPECTIVE STUDIES; RIFAMYCINS; SULFAMETHOXAZOLE; TRAVEL; TRIMETHOPRIM;

EID: 0031771908     PISSN: 00122823     EISSN: None     Source Type: Journal    
DOI: 10.1159/000007580     Document Type: Article

References (27)

1. DuPont H, Ericsson C: Prevention and treatment of travelers' diarrhea. N Engl J Med 1993;328:1821-1827.
2. DuPont H, Reves R, Galindo R, Sullivan P, Wood L, Mendiola J: Treatment of travelers' diarrhea with trimethoprim/sulfamethoxazole and with trimethoprim alone. N Engl J Med 1982;307:841-844.
3. Murray B, Alvarado T, Kim K-H, et al: Increasing resistance to trimethoprim-sulfamethoxazole among isolates of Escherichia coli in developing countries. J Infect Dis 1985;152:1107-1113.
4. Ericsson C, DuPont H, Mathewson J: Single dose ofloxacin plus loperamide compared with single dose or three days of ofloxacin in the treatment of travelers' diarrhea. J Travel Med 1997;4:3-7.
5. Ericsson C, DuPont H, Sullivan P, Galindo E, Evans D, Evans D Jr: Bicozamycin, a poorly absorbable antibiotic, effectively treats travelers' diarrhea. Ann Intern Med 1983;98:20-25.
6. DuPont H, Ericsson C, Mathewson J, de la Cabada F, Conrad D: Oral aztreonam, a poorly absorbed yet effective therapy tor bacterial diarrhea in US travelers to Mexico. JAMA 1992; 267:1932-1935.
7. Alvisi V, D'Ambrosi A, Loponte A, et al: Rifaximin, a rifamycin derivative for use in the treatment of intestinal bacterial infections in seriously disabled patients. J Int Med Res 1987;15: 49-56.
8. Hoover W, Gerlach E, Hoban D, Eliopoulos G, Pfaller M, Jones R: Antimicrobial activity and spectrum of rifaximin, a new topical rifamycin derivative. Diagn Microbiol Infect Dis 1993; 16:111-118.
9. Descombe J, Dubourg D, Picard M, Palazzini E: Pharmacokinetic study of rifaximin after oral administration in healthy volunteers. Int J Clin Pharmacol Res 1994;14:51-56.
10. Gillis J, Brogden R: Rifaximin: A review of its antibacterial activity, pharmacokinetic properties and therapeutic potential in conditions mediated by gastrointestinal bacteria. Drugs 1995; 49:467-484.
11. Bandres J, Mathewson J, Ericsson C, DuPont H: Trimethoprim/sulfamethoxazole remains active against enterotoxigenic Escherichia coli and Shigella spp in Guadalajara, Mexico. Am J Med Sci 1992;303:289-291.
12. Ericsson C, Johnson P, DuPont H, Morgan D, Bitsura J: Ciprofloxacin and trimethoprim/sulfamethoxazole as initial therapy for acute travelers' diarrhea. A placebo-controlled randomized trial. Ann Intern Med 1987;106:216-220.
13. Gorbach S, Edelman R: Travelers' diarrhea: National Institutes of Health Consensus Development Conference. Rev Infect Dis 1986; 8(suppl2):109-233.
14. Gorbach S, Kean B, Evans D, Evans D Jr, Bessudo D: Travelers' diarrhea and toxigenic Escherichia coli. N Engl J Med 1975;292:933-936.
15. Echeverria P, Sack R, Blacklow N, Bodhidatta P, Rowe B, McFarland A: Prophylactic doxycycline for travelers' diarrhea in Thailand: Further supportive evidence of Aeromonas hydrophila as an enteric pathogen. Am J Epidemiol 1984;120:912-921.
16. Sack R, Santosham M, Froehlich J, Medina C, Orskov F, Orskov I: Doxycycline prophylaxis of travelers' diarrhea in Honduras, an area where resistance to doxycycline is common among enterotoxigenic Escherichia coli. Am J Trop Med Hyg 1984;33:460-466.
17. Taylor D, Echeverria P: Etiology and epidemiology of travelers' diarrhea in Asia. Rev Infect Dis 1986;8(suppl 2):136-141.
18. Wistrom J, Jertborn M, Hedstrom S, et al: Short-term self-treatment of travelers' diarrhoea with norfloxacin: A placebo-controlled study. J Antimicrob Chemother 1989;23:905-913.
19. Farthing M, DuPont H, Guandalini S, Keusch G, Steffen R: Treatment and prevention of travelers' diarrhoea. Gastroenterol Int 1992;5: 162-175.
20. Rautelin H, Renkonen O, Kosunen T: Emergence of fluoroquinolone resistance in Campylobacter jejuni and Campylobacter coli in subjects from Finland. Antimicrob Agents Chemother 1991;35:2065-2069.
21. Segreti J, Gootz T, Goodman L, et al: High-level quinolone resistance in clinical isolates of Campylobacter jejuni. J Infect Dis 1992;165: 667-670.
22. Kuschner R, Trofa A, Thomas R, et al: Use of azithromycin for the treatment of campylobacter enteritis in travelers to Thailand, an area where ciprofloxacin resistance is prevalent. Clin Infect Dis 1995;21:536-541.
23. Corazza G, Ventrucci M, Strocchi A, et al: Treatment of small intestine bacterial overgrowth with rifaximin, a non-absorbable rifamycin. J Int Med Res 1988;16:312-316.
24. Venturini A: Pharmacokinetics of L/105, a new rifamycin, in rats and dogs, after oral administration. Chemotherapy 1983;29:1-3.
25. Soro O, Pesce A, Raggi M, Debbia E, Shito C: Selection of rifampicin-resistant Mycobacterium tuberculosis does not occur in the presence of low concentrations of rifaximin. Clin Microbiol Infect 1997;3:147-151.
26. Haltalin K, Nelson J, Hinton L, Kusmiesz H, Sladoje M: Comparison of orally absorbable and non-absorbable antibiotics in shigellosis: A double blind study with ampicillin and neomycin. J Pediatr 1968;72:708-720.
27. Nishida M, Mine Y, Nonoyama S, Kamimura T, Fukada S: Therapeutic efficacy of bicyclomycin for shigellosis experimentally induced in rhesus monkeys. J Antibiot 1974;27:976-983.