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Volumn 28, Issue 2, 1998, Pages 77-89

Cytokine mRNA profile of myelin basic protein reactive T-cell clones in patients with multiple sclerosis

Author keywords

Cytokine; MBP specific T cell clones; Multiple sclerosis

Indexed keywords

CYTOKINE; HLA DR2 ANTIGEN; INTERLEUKIN 10; MESSENGER RNA; MYELIN BASIC PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 0031771184     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.3109/08916939809003870     Document Type: Article
Times cited : (12)

References (37)
  • 2
    • 0031025835 scopus 로고    scopus 로고
    • Autoimmune pathogenesis of multiple sclerosis: Role of autoreactive T lymphocytes and new immunotherapeutic strategies
    • Stinissen, P., Raus, J. and Zhang, J., Autoimmune pathogenesis of multiple sclerosis: role of autoreactive T lymphocytes and new immunotherapeutic strategies. Crit. Rev Immunol. 1997; 17: 33-75.
    • (1997) Crit. Rev Immunol. , vol.17 , pp. 33-75
    • Stinissen, P.1    Raus, J.2    Zhang, J.3
  • 3
    • 0020334818 scopus 로고
    • The genetics of susceptibility to Multiple Sclerosis
    • Spielman, R.S. and Nathanson, N., The genetics of susceptibility to Multiple Sclerosis. Epidemiol. Rev. 1982; 4: 45-65.
    • (1982) Epidemiol. Rev. , vol.4 , pp. 45-65
    • Spielman, R.S.1    Nathanson, N.2
  • 4
    • 0027957780 scopus 로고
    • Increased frequency of IL-2 responsive T-cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis
    • Zhang, J.W., Markovic, S., Lacet, B., Raus, J., Weiner, H.L. and Hafler, D.A., Increased frequency of IL-2 responsive T-cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis. J. Exp. Med. 1994; 179: 973-984.
    • (1994) J. Exp. Med. , vol.179 , pp. 973-984
    • Zhang, J.W.1    Markovic, S.2    Lacet, B.3    Raus, J.4    Weiner, H.L.5    Hafler, D.A.6
  • 5
    • 0027406406 scopus 로고
    • Selection for T-cell receptor Vß-Dß-Jß gene rearrangements with specificity for a myelin basic protein peptide in the brain lesions of multiple sclerosis
    • Oksenberg, J., Panzara, M.A., Begovich, B., Mitchell, D., Erlich, H.A., Murray, R.S. et al. Selection for T-cell receptor Vß-Dß-Jß gene rearrangements with specificity for a myelin basic protein peptide in the brain lesions of multiple sclerosis. Nature 1993; 162: 68-70.
    • (1993) Nature , vol.162 , pp. 68-70
    • Oksenberg, J.1    Panzara, M.A.2    Begovich, B.3    Mitchell, D.4    Erlich, H.A.5    Murray, R.S.6
  • 6
    • 0026042680 scopus 로고
    • Preferential T cell receptor beta chain variable gene use in MBP-reactive T cell clones from patients with multiple sclerosis
    • Kotzin, B.L., Karuturi, S., Chou, Y.K. et al. Preferential T cell receptor beta chain variable gene use in MBP-reactive T cell clones from patients with multiple sclerosis. Proc. Natl. Acad. Sci. USA 1991; 88: 9161-9165.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 9161-9165
    • Kotzin, B.L.1    Karuturi, S.2    Chou, Y.K.3
  • 7
    • 0026066932 scopus 로고
    • Cytokine levels in the cerebrospinal fluid and sera of patients with multiple sclerosis
    • Maimone, D., Gregory, S., Arnason, B.G.W. and Reder, A.T. Cytokine levels in the cerebrospinal fluid and sera of patients with multiple sclerosis. J. Neuroimmunol. 1991; 32: 67-74.
    • (1991) J. Neuroimmunol. , vol.32 , pp. 67-74
    • Maimone, D.1    Gregory, S.2    Arnason, B.G.W.3    Reder, A.T.4
  • 8
    • 0027497847 scopus 로고
    • Correlation of interleukin-2 and soluble interleukin-2 receptor with clinical activity of multiple sclerosis
    • Sharief, M.K. and Thompson, E.J. Correlation of interleukin-2 and soluble interleukin-2 receptor with clinical activity of multiple sclerosis. J. Neurol. Neurosurg. Psychiatry 1993; 56: 156-174.
    • (1993) J. Neurol. Neurosurg. Psychiatry , vol.56 , pp. 156-174
    • Sharief, M.K.1    Thompson, E.J.2
  • 9
    • 0028954854 scopus 로고
    • Semi-quantitative analysis of cytokine gene expression in blood and cerebrospinal fluid cells by reverse transcriptase polymerase chain reaction
    • Rieckmann, P., Albrecht, M., Ehrenreich, H., Weber, T. and Michel, U. Semi-quantitative analysis of cytokine gene expression in blood and cerebrospinal fluid cells by reverse transcriptase polymerase chain reaction. J. Exp. Med. 1995; 195: 17-29.
    • (1995) J. Exp. Med. , vol.195 , pp. 17-29
    • Rieckmann, P.1    Albrecht, M.2    Ehrenreich, H.3    Weber, T.4    Michel, U.5
  • 10
    • 0025013169 scopus 로고
    • Autoreactive T lymphocytes in multiple sclerosis determined by antigen-induced secretion of interferon-γ
    • Olsson, T., Wang, W-Z., Höjeberg, B., Kostulas, V., Jiang, Y.-P., Andersson, G. et al. Autoreactive T lymphocytes in multiple sclerosis determined by antigen-induced secretion of interferon-γ. J. Clin. Invest. 1990; 86: 981-985.
    • (1990) J. Clin. Invest. , vol.86 , pp. 981-985
    • Olsson, T.1    Wang, W.-Z.2    Höjeberg, B.3    Kostulas, V.4    Jiang, Y.-P.5    Andersson, G.6
  • 11
    • 0028260294 scopus 로고
    • Organ-specific autoantigens induce interferon-γ. and interleukin-4 mRNA expression in mono-nuclear cells in multiple sclerosis and myasthenia gravis
    • Link, J., Söderström, M., Ljungdalh, A., Hojeberg, B., Olsson, T., Xu, Z. et al. Organ-specific autoantigens induce interferon-γ. and interleukin-4 mRNA expression in mono-nuclear cells in multiple sclerosis and myasthenia gravis. Neurology 1994; 44: 728-734.
    • (1994) Neurology , vol.44 , pp. 728-734
    • Link, J.1    Söderström, M.2    Ljungdalh, A.3    Hojeberg, B.4    Olsson, T.5    Xu, Z.6
  • 12
    • 0028191903 scopus 로고
    • Interferon-gamma, interleukin-4 and transforming growth factor-beta mRNA expression in multiple sclerosis and myasthenia gravis
    • Link, J. Interferon-gamma, interleukin-4 and transforming growth factor-beta mRNA expression in multiple sclerosis and myasthenia gravis. Acta. Neurol. Scand. Suppl. 1994; 158: 1-58.
    • (1994) Acta. Neurol. Scand. Suppl. , vol.158 , pp. 1-58
    • Link, J.1
  • 13
    • 0023221133 scopus 로고
    • Treatment of multiple sclerosis with gamma interferon: Exacerbations associated with activation of the immune system
    • Panitch, H.S., Hirsch, R.L., Schindler, J. and Johnson, K.P. Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system. Neurology 1987; 37: 1097-1102.
    • (1987) Neurology , vol.37 , pp. 1097-1102
    • Panitch, H.S.1    Hirsch, R.L.2    Schindler, J.3    Johnson, K.P.4
  • 14
    • 0028985320 scopus 로고
    • Tumor necrosis factor-alpha messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity
    • Rieckmann, P., Albrecht, M., Kitze, B., Weber, T., Tumani, H., Broocks, A. et al. Tumor necrosis factor-alpha messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity. Ann. Neurol 1995; 37: 82-88.
    • (1995) Ann. Neurol , vol.37 , pp. 82-88
    • Rieckmann, P.1    Albrecht, M.2    Kitze, B.3    Weber, T.4    Tumani, H.5    Broocks, A.6
  • 15
    • 0028241924 scopus 로고
    • Defective production of anti-inflammatory cytokine. TGF-beta by T-cell lines of putients with active multiple sclerosis
    • Mokhtarian, P., Shi, Y., Shirazian, D., Morgante, L., Miller, A. and Grob, D. Defective production of anti-inflammatory cytokine. TGF-beta by T-cell lines of putients with active multiple sclerosis. J. Immunol. 1994; 152: 6003-6010.
    • (1994) J. Immunol. , vol.152 , pp. 6003-6010
    • Mokhtarian, P.1    Shi, Y.2    Shirazian, D.3    Morgante, L.4    Miller, A.5    Grob, D.6
  • 16
    • 0024366885 scopus 로고
    • Tumor necrosis factor identified in multiple sclerosis brain
    • Hofman, K.M., Hinton, D.R., Johnson, K. and Merrill, J.E. Tumor necrosis factor identified in multiple sclerosis brain. J. Exp. Med. 1989; 170: 607-612.
    • (1989) J. Exp. Med. , vol.170 , pp. 607-612
    • Hofman, K.M.1    Hinton, D.R.2    Johnson, K.3    Merrill, J.E.4
  • 17
    • 0023904746 scopus 로고
    • Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro
    • Selmaj, K. and Raine, C.S. Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann. Neurol. 1988; 23: 339-346.
    • (1988) Ann. Neurol. , vol.23 , pp. 339-346
    • Selmaj, K.1    Raine, C.S.2
  • 19
    • 0019986548 scopus 로고
    • Experimental autoimmune encephalomyelitis (EAE) mediated by T-cell lines: Process of selection of lines and characterization of the cells
    • Ben-Nun, A. and Cohen, I.R. Experimental autoimmune encephalomyelitis (EAE) mediated by T-cell lines: process of selection of lines and characterization of the cells. J. Immunol. 1982; 129: 303-309.
    • (1982) J. Immunol. , vol.129 , pp. 303-309
    • Ben-Nun, A.1    Cohen, I.R.2
  • 20
    • 0023232366 scopus 로고
    • Two types of mouse helper T-cell clones
    • Mosmann, T.R. and Coffman, R.L. Two types of mouse helper T-cell clones. Immunology Today 1987; 8: 223-227.
    • (1987) Immunology Today , vol.8 , pp. 223-227
    • Mosmann, T.R.1    Coffman, R.L.2
  • 21
    • 0025313253 scopus 로고
    • Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T-cell clones correlates with encephalitogemcity
    • Powell, M.B., Mitchell, D., Lederman, J., Buckmeier, J., Zamvil, S.S., Graham, M. et al. Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T-cell clones correlates with encephalitogemcity. Int. Immunol. 1990; 2: 539-544.
    • (1990) Int. Immunol. , vol.2 , pp. 539-544
    • Powell, M.B.1    Mitchell, D.2    Lederman, J.3    Buckmeier, J.4    Zamvil, S.S.5    Graham, M.6
  • 22
    • 0028876611 scopus 로고
    • Retinoid treatment of experimental allergic encephalomyelitis. IL-4 production correlates with improved disease course
    • Racke, M.K., Burnett, D., Pak, S.H., Albert, P.S., Cannella, B., Raine, C.S. et al. Retinoid treatment of experimental allergic encephalomyelitis. IL-4 production correlates with improved disease course. J. Immunol. 1995; 154: 450-458.
    • (1995) J. Immunol. , vol.154 , pp. 450-458
    • Racke, M.K.1    Burnett, D.2    Pak, S.H.3    Albert, P.S.4    Cannella, B.5    Raine, C.S.6
  • 23
    • 0027134598 scopus 로고
    • Fine-specificity differences in the recognition of an encephalitogenic peptide by T helper 1 and 2 cells
    • Van der Veen, R.C., Kapp, J.A. and Trotter, J.L. Fine-specificity differences in the recognition of an encephalitogenic peptide by T helper 1 and 2 cells. J. Neuroimmunol. 1993; 48: 221-226.
    • (1993) J. Neuroimmunol. , vol.48 , pp. 221-226
    • Van Der Veen, R.C.1    Kapp, J.A.2    Trotter, J.L.3
  • 24
    • 0020686503 scopus 로고
    • New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
    • Poser, C.M., Paly, D.W., Scheinberg, L., Mc Donald, I., Davis, F., Ebers, G. et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann. Neurol. 1983; 13: 227-231.
    • (1983) Ann. Neurol. , vol.13 , pp. 227-231
    • Poser, C.M.1    Paly, D.W.2    Scheinberg, L.3    Mc Donald, I.4    Davis, F.5    Ebers, G.6
  • 25
    • 0026641148 scopus 로고
    • Myelin basic protein-specific T lymphocytes in multiple sclerosis and controls: Precursor frequency, fine specificity, and cytotoxicity
    • Zhang, J.W., Medaer, R., Chin, Y., van den Bergh-Loonen, E., Raus, J. Myelin basic protein-specific T lymphocytes in multiple sclerosis and controls: precursor frequency, fine specificity, and cytotoxicity. Ann. Neurol. 1992; 32: 330-338.
    • (1992) Ann. Neurol. , vol.32 , pp. 330-338
    • Zhang, J.W.1    Medaer, R.2    Chin, Y.3    Van Den Bergh-Loonen, E.4    Raus, J.5
  • 26
    • 0027448708 scopus 로고
    • MHC-restricted depletion of human myelin basic protein-reactive T-cells by T-cell vaccination
    • Zhang, J.W., Medaer, R., Stinissen, P., Hafler, D. and Raus, J. MHC-restricted depletion of human myelin basic protein-reactive T-cells by T-cell vaccination. Science 1993; 216: 1451-1454.
    • (1993) Science , vol.216 , pp. 1451-1454
    • Zhang, J.W.1    Medaer, R.2    Stinissen, P.3    Hafler, D.4    Raus, J.5
  • 27
    • 0028951840 scopus 로고
    • Clonal expansion of myelin basic protein-reactive T-cells in patients with multiple sclerosis: Restricted T-cell receptor V gene rearrangements and CDR3 sequence
    • Vandevyver, C., Mertens, N., van den Elsen, P., Medaer, R., Raus, J. and Zhang, J. Clonal expansion of myelin basic protein-reactive T-cells in patients with multiple sclerosis: restricted T-cell receptor V gene rearrangements and CDR3 sequence. Eur. J. Immunol. 1995; 25: 958-968.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 958-968
    • Vandevyver, C.1    Mertens, N.2    Van Den Elsen, P.3    Medaer, R.4    Raus, J.5    Zhang, J.6
  • 28
    • 0026953017 scopus 로고
    • Simultaneous quantification of cytokine mRNAs in interleukin-1ß stimulated U373 human astrocytoma cells by a polymerisation chain reaction method involving co-amplification with an internal multi-specific control
    • Legoux, P., Minty, C., Delpech, B., Minty, A.J. and Shire, D. Simultaneous quantification of cytokine mRNAs in interleukin-1ß stimulated U373 human astrocytoma cells by a polymerisation chain reaction method involving co-amplification with an internal multi-specific control. Eur. Cytokine Netw. 1992; 3: 553-563.
    • (1992) Eur. Cytokine Netw. , vol.3 , pp. 553-563
    • Legoux, P.1    Minty, C.2    Delpech, B.3    Minty, A.J.4    Shire, D.5
  • 29
    • 0028851882 scopus 로고
    • Quantification of cytokine mRNA expression by RT-PCR and electrochemiluminescence
    • Vandevyver, C., Motmans, K. and Raus, J. Quantification of cytokine mRNA expression by RT-PCR and electrochemiluminescence. Genome Research 1995; 5: 195-201.
    • (1995) Genome Research , vol.5 , pp. 195-201
    • Vandevyver, C.1    Motmans, K.2    Raus, J.3
  • 30
    • 0028802606 scopus 로고
    • Genetic control of multiple sclerosis: Increased production of lymphotoxin and tumor necrosis factor-alpha by HLA-DR2+ T-cells
    • Zipp, K., Weber, S., Huber, S., Sotgiu, S., Cslonkowska, A., Holler, E. et al. Genetic control of multiple sclerosis: increased production of lymphotoxin and tumor necrosis factor-alpha by HLA-DR2+ T-cells, Ann. Neurol. 1995; 38: 723-730.
    • (1995) Ann. Neurol. , vol.38 , pp. 723-730
    • Zipp, K.1    Weber, S.2    Huber, S.3    Sotgiu, S.4    Cslonkowska, A.5    Holler, E.6
  • 31
    • 0029395717 scopus 로고
    • Expression of IFN-γ. IL-4 and TGF-8 in multiple sclerosis in relation to HLA-Dw2 phenotype and stage of disease
    • Söderström, M., Hillert, J., Link, J., Navikas, V., Fredrikson, S. and Link, H. Expression of IFN-γ. IL-4 and TGF-8 in multiple sclerosis in relation to HLA-Dw2 phenotype and stage of disease. Multiple Sclerosis 1995; 1: 173-180.
    • (1995) Multiple Sclerosis , vol.1 , pp. 173-180
    • Söderström, M.1    Hillert, J.2    Link, J.3    Navikas, V.4    Fredrikson, S.5    Link, H.6
  • 32
    • 0030844435 scopus 로고    scopus 로고
    • The cytokine profile of human myelin basic protein-reactive T cells in multiple sclerosis patients and healthy individuals
    • Hermans, G., Stinissen, P., Hauben, L., van den Bergh-Loonen, L., Raus, J. and Zhang, J. The cytokine profile of human myelin basic protein-reactive T cells in multiple sclerosis patients and healthy individuals. Ann. Neurol. 1997; 42: 18-27.
    • (1997) Ann. Neurol. , vol.42 , pp. 18-27
    • Hermans, G.1    Stinissen, P.2    Hauben, L.3    Van Den Bergh-Loonen, L.4    Raus, J.5    Zhang, J.6
  • 33
    • 0029743819 scopus 로고    scopus 로고
    • Cytokine phenotype of human autoreactivc T cell clones specific for the immuno-dominant myelin basic protein peptide (83-99)
    • Hemmer, B., Vcrgelli, M., Calabresi, P., Huang, T., McFarland, H.F. and Martin, R. Cytokine phenotype of human autoreactivc T cell clones specific for the immuno-dominant myelin basic protein peptide (83-99). J. Neurosc. Res. 1996; 45: 852-862.
    • (1996) J. Neurosc. Res. , vol.45 , pp. 852-862
    • Hemmer, B.1    Vcrgelli, M.2    Calabresi, P.3    Huang, T.4    McFarland, H.F.5    Martin, R.6
  • 34
    • 0025820259 scopus 로고
    • Restricted T-cell expression of IL-2/IFN-γ mRNA in human inflammatory disease
    • Brod, S.A., Benjamin, D. and Hafler, D. Restricted T-cell expression of IL-2/IFN-γ mRNA in human inflammatory disease. J. Immunol. 1991; 147: 810-815.
    • (1991) J. Immunol. , vol.147 , pp. 810-815
    • Brod, S.A.1    Benjamin, D.2    Hafler, D.3
  • 35
    • 0027204621 scopus 로고
    • Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T-cell clones and inhibits their antigen-specific proliferation and cytokine production
    • Del Prete, G., DeCarli, M., Almerigogna, F., Giudizi, M.G., Biagiotti, R. and Romagnani, S. Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T-cell clones and inhibits their antigen-specific proliferation and cytokine production. J. Immunol. 1993; 150: 353-360.
    • (1993) J. Immunol. , vol.150 , pp. 353-360
    • Del Prete, G.1    DeCarli, M.2    Almerigogna, F.3    Giudizi, M.G.4    Biagiotti, R.5    Romagnani, S.6
  • 36
    • 0025778577 scopus 로고
    • Tumour necrosis factor-alpha synthesis by cerebrospinal-fluid-derived T cell clones from patients with multiple sclerosis
    • Benvenuto, R., Paroli, M., Buttinelli, C., Franco, A., Barnaba, V., Fieschi, C. and Balsano, F. Tumour necrosis factor-alpha synthesis by cerebrospinal-fluid-derived T cell clones from patients with multiple sclerosis. Clin. Exp. Immunol. 1991; 84: 97-102.
    • (1991) Clin. Exp. Immunol. , vol.84 , pp. 97-102
    • Benvenuto, R.1    Paroli, M.2    Buttinelli, C.3    Franco, A.4    Barnaba, V.5    Fieschi, C.6    Balsano, F.7
  • 37
    • 0026697915 scopus 로고
    • Cytokines in neuroinflammatory disease: Role of myelin autoreactive T cell production of interferon-gamma
    • Olsson, T. Cytokines in neuroinflammatory disease: role of myelin autoreactive T cell production of interferon-gamma. J. Neuroimmunol. 1992; 40: 211-218.
    • (1992) J. Neuroimmunol. , vol.40 , pp. 211-218
    • Olsson, T.1


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