Effects of dopamine, dobutamine, dopexamine, phenylephrine, and saline solution on intramuscular blood flow and other cardiopulmonary variables in halothane-anesthetized ponies

American Journal of Veterinary Research

Volumn 59, Issue 11, 1998, Pages 1463-1472

  Lee, Y H L ^a,b   Clarke, K W ^a   Alibhai, H I K ^a   Song, D ^a,c  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c Equine Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

DIAZEPAM; DOBUTAMINE; DOPAMINE; DOPEXAMINE; HALOTHANE; KETAMINE; PHENYLEPHRINE; XYLAZINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD FLOWMETRY; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; HEART ARRHYTHMIA; HORSE; HYPERTENSION; INHALATION ANESTHESIA; LASER DOPPLER FLOWMETRY; MALE; MEAN ARTERIAL PRESSURE; MUSCLE BLOOD FLOW; NONHUMAN; VASCULAR RESISTANCE;

ANESTHETICS, INHALATION; ANIMALS; BLOOD PRESSURE; CARDIAC OUTPUT; CARDIOTONIC AGENTS; CARDIOVASCULAR SYSTEM; DOBUTAMINE; DOPAMINE; DRUG EVALUATION; FEMALE; FORELIMB; HALOTHANE; HORSES; LAMENESS, ANIMAL; LASER-DOPPLER FLOWMETRY; MALE; MUSCLE, SKELETAL; PHENYLEPHRINE; REGIONAL BLOOD FLOW; SODIUM CHLORIDE; VASCULAR RESISTANCE; VASODILATOR AGENTS;

EID: 0031770842     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Clarke KW, Gerring EEL. Detomidine as a sedative and premedicant in the horse (1985-1990), in Proceedings. Annu Meet Am Assoc Equine Pract 1990;35:629-635.
2. Johnston GM, Taylor PM, Holmes MA et al. Confidential enquiry of perioperative equine fatalities (CEPEF-1): preliminary results. Equine Vet J 1995;27:193-200.
3. Tevik A. The role of anesthesia in surgical mortality in horses. Nord Vet Med 1983;35:175-179.
4. Young SS, Taylor PM. Factors influencing the outcome of equine anaesthesia: a review of 1,314 cases. Equine Vet J 1993;25: 147-151.
5. Richey MT, Holland MS, McGrath C, et al. Equine postanesthetic lameness: a retrospective study. Vet Surg 1990; 19:392-397.
6. Dodman NH, Gray L, Williams R, et al. Intracompartmental muscle pressure, temperature and pH in the horse under general anesthesia. J Equine Vet Sci 1985;5:11-15.
7. Grandy JL, Steffey EP, Hodgson DS, et al. Arterial hypotension and the development of postanesthetic myopathy in halothane anesthetized horses. Am J Vet Res 1987;48:192-197.
8. Klein L. A review of fifty cases of post-operative myopathy in the horse - intrinsic and managing factors affecting risk, in Proceedings. Annu Meet Am Assoc Equine Pract 1978;24:89-94.
9. Lindsay WA, McDonell W, Bignell W. Equine postanesthetic forelimb lameness: intracompartmental muscle pressure changes and biochemical patterns. Am J Vet Res 1980;41: 1919-1924.
10. Lindsay WA, Pascoe PJ, McDonell WN, et al. Effect of protective padding on forelimb intracompartmental pressures in anesthetized horses. Am J Vet Res 1985;46:688-691.
11. Lindsay WA, Robinson GM, Brunson DB, et al. Induction of equine postanesthetic myositis after halothane-induced hypotension. Am J Vet Res 1989;50:404-410.
12. McDonell WN, Pascoe PJ, Lindsay WA, et al. Evaluation of the wick catheter as used to measure intracompartmental muscle pressure in equine muscle. Am J Vet Res 1985;46:684-687.
13. Norman WM, Dodman NH, Court MH. Interstitial pH and pressure in the dependent biceps femoris muscle of laterally recumbent anesthetized horses. Vet Surg 1988;17:234-239.
14. Taylor PM, Young SS. The effect of limb position on venous and compartmental pressure in the forelimb of ponies. J Vet Anaesth 1990;17:35-37.
15. White NA, Suarez M. Change in triceps muscle intracompartmental pressure with repositioning and padding of the lower-most thoracic limb of the horse. Am J Vet Res 1986;47:2257-2260.
16. Matsen FA. Compartmental syndrome. New York: Grune & Stratton, 1980.
17. Daunt DA. Supportive therapy in the anesthetized horse. Vet Clin North Am Equine Pract 1990;6:557-574.
18. Muir WW, McGuirk S. Cardiovascular drugs. Vet Clin North Am Equine Pract 1987;3:37-57.
19. Steffey EP, Howland D Jr. Cardiovascular effects of halothane in the horse. Am J Vet Res 1978;39:611-615.
20. 133Xe clearance and laser Doppler flowmetry in assessment of blood flow changes in human masseter muscle induced by isometric contraction. Arch Oral Biol 1989;34:779-786.
21. Serteyn D, Mottart E, Michaux C, et al. Laser Doppler flowmetry: muscular microcirculation in anaesthetised horses. Equine Vet J 1986;18:391-395.
22. Serteyn D, Coppens P, Mottart E, et al. Measurement of muscular microcirculatibn by laser Doppler flowmetry in isoflurane and halothane anaesthetised horses. Vet Rec 1987;122:324-326.
23. Serteyn D, Lavergne L, Coppens P, et al. Equine postanaesthetic myositis: muscular post ischaemic hyperaemia measured by laser Doppler flowmetry. Vet Rec 1988;123:126-128.
24. Nilsson GE, Tenland T, Oberg PA. Evaluation of a laser Doppler flowmeter for measurement of tissue blood flow. Trans Biomed Eng 1980;27:597-604.
25. Ahn LH, Lindhagen J, Lundgren O. Assessment of blood flow in the small intestine with laser Doppler flowmetry. Scand J Gastroenterol 1986;21:863-870.
26. Ahn LH, Lindhagen J, Lundgren O. Measurement of colonic blood flow with laser Doppler flowmetry. Scand J Gastroenterol 1986;21:871-880.
27. Bonner RF, Clem TR, Bowen PD, et al. Laser Doppler continuous real time monitor of pulsatile and mean blood flow in tissue microcirculation. In: Chen S-H, Chu B, Nossal R, eds. Scattering techniques applied to supramolecular and non-equilibrium systems. New York: Plenum Press, 1981;685-702.
28. Almond NE, Wheatley AM. Measurement of hepatic perfusion in rats by laser Doppler flowmetry. Am J Physiol 1992;262:G203-G209.
29. Cederholm I, Ecers H, Lofstrom JB. Effect of intradermal injection of saline or a local anaesthetic agent on skin blood flow - a methodological study in man. Acta Anaesthesiol Scand 1991;35:208-215.
30. Dyson DH, Pascoe PJ. Influence of preinduction methoxamine, lactated Ringer solution, or hypertonic saline solution infusion or postinduction dobutamine infusion on anesthetic-induced hypotension in horses. Am J Vet Res 1990;51:17-21.
31. Gasthuys F, De Moor A, Parmentier D. Influence of dopamine and dobutamine on the cardiovascular depression during a standard halothane anesthesia in dorsally recumbent, ventilated ponies. Zentralbl Veterinarmed [A] 1991;38:494-500.
32. Gasthuys F, Messeman C, De Moor A. Cardiovascular effects of 7.2% hypertonic saline solution in halothane anaesthetised ponies. J Vet Anaesth 1994;21:60-65.
33. Hinchcliff KW, McKeever KH, Muir WW. Hemodynamic effects of atropine, dobutamine, nitroprusside, phenylephrine and propranolol in conscious horses. J Vet Intern Med 1991;5:80-86.
34. Swanson CR, Muir WW III, Bednarski RM, et al. Hemodynamic responses in halothane-anesthetized horses given infusions of dopamine or dobutamine. Am J Vet Res 1985;46: 365-370.
35. Swanson CR, Muir WW. Dobutamine-induced augmentation of cardiac output does not enhance respiratory gas exchange in anesthetized recumbent healthy horses. Am J Vet Res 1986;47:1573-1576.
36. Swanson CR, Muir WW III. Hemodynamic and respiratory responses in halothane-anesthetized horses exposed to positive end-expiratory pressure alone and with dobutamine. Am J Vet Res 1988;49:539-542.
37. Trim CM, Moore JN, White NA. Cardiopulmonary effects of dopamine hydrochloride in anaesthetised horses. Equine Vet J 1985;17:41-44.
38. Trim CM, Moore JN, Hardee MM, et al. Effects of an infusion of dopamine on the cardiopulmonary effects of Escherichia coli endotoxin in anaesthetised horses. Res Vet Sci 1991;50:54-63.
39. Muir WW. Cardiovascular effects of dopexamine HCL in conscious and halothane-anaesthetised horses. Equine Vet J 1992;24(Suppl 11):24-29.
40. Muir WW III. Inotropic mechanism of dopexamine hydrochloride in horses. Am J Vet Res 1992;53:1343-1346.
41. Young LE, Blissitt KJ, Clutton RE, et al. Temporal effects of an infusion of dopexamine hydrochloride in horses anesthetized with halothane. Am J Vet Res 1997;58:516-523.
42. Ciba Geigy. Scientific tables. In: Heart and circulation. Vol 5. 8th ed. Basel, XXXXX: Ciba Geigy, 1994;40.
43. Gleed RD, Dobson A. Effect of clenbuterol on arterial oxygen tension in the anaesthetised horse. Res Vet Sci 1990;48:331-337.
44. Luna SPL, Taylor PM. Pituitary-adrenal and opioid release in ponies during thiopentone/halothane anaesthesia. Res Vet Sci 1995;58:35-41.
45. Hoffman BB, Lefkowitz RJ. Catecholamines and sympathomimetic drugs. In: Gilman AG, Rall TW, Nies AS, et al, eds. The pharmacological basis of therapeutics. 8th ed. New York: Pergamon Press. 1990;187-220.
46. Wertz EM, Dunlop DI, Wagner AE, et al. Cardiovascular and oxygenation responses to dobutamine and dopamine in halothane anesthetized horses. Vet Surg 1992;21:501-502.
47. Trim CM, Adams JG, Cowgill LM, et al. A retrospective survey of anaesthesia in horses with colic. Equine Vet J 1989;(Suppl 7):84-90.
48. Moss J, Craigo PA. The autonomic system. In: Miller RD, ed. Anesthesia. 4th ed. New York: Churchill Livingstone Inc, 1994;523-575.
49. Bass AS. Contrasting effects of dopexamine hydrochloride on electrolyte excretion in canine kidney. J Pharmacol Exp Ther 1990;253:798-802.