Heart rate and flow velocity variability as determined from umbilical Doppler velocimetry at 10-20 weeks of gestation

Clinical Science

Volumn 95, Issue 5, 1998, Pages 539-545

  Ursem, Nicolette T C ^a   Struijk, Piet C ^a   Hop, Wim C J ^b   Clark, Edward B ^c   Keller, Bradley B ^d   Wladimiroff, Juriy W ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^c PRIMARY CHILDREN'S MEDICAL CENTER   (United States)

^d UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Doppler ultrasound; Flow velocity variability; Heart rate variability; Umbilical artery

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BLOOD FLOW VELOCITY; CHOLINERGIC SYSTEM; CLINICAL TRIAL; DOPPLER FLOWMETRY; FEEDBACK SYSTEM; FEMALE; FETUS; FETUS HEART RATE; HEART RATE VARIABILITY; HEMODYNAMICS; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; REGRESSION ANALYSIS; SECOND TRIMESTER PREGNANCY; SYSTOLIC BLOOD PRESSURE; UMBILICAL ARTERY;

EID: 0031770771     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs0950539     Document Type: Article

References (26)

1. Breborowicz, G., Moczko, J. and Gadzinowski, J. (1988) Quantification of the total heart rate variability by spectral analysis in growth-retarded fetuses. Gynecol. Obstet. Invest. 25, 186-191
2. Wladimiroff, J. W. and Seelen, J. C. (1972) Fetal heart action in early pregnancy. Development of fetal vagal function. Eur. J. Obstet. Gynecol. 2, 55-63
3. Schifferli, P. Y. and Caldeyro-Barcia, R. (1973) Effects of atropine and beta-adrenergic drugs on the heart rate of the human fetus. In Fetal Pharmacology (Boréus, L., ed.), pp. 259-279, Raven Press, New York
4. Pillai, M. and James, D. (1990) The development of fetal heart rate patterns during normal pregnancy. Obstet. Gynecol. 76, 812-816
5. Wladimiroff, J. W., Huisman, T. W. and Stewart, P. A. (1991) Fetal and umbilical flow velocity waveforms between 10-16 weeks' gestation: a preliminary study. Obstet. Gynecol. 78, 812-814
6. Splunder van, I. P., Huisman, T. W. A., Ridder de, M. A. J. and Wladimiroff, J. W. (1996) Fetal venous arterial flow velocitiy waveforms between 8 and 20 weeks of gestation. Pediatr. Res. 40, 158-162
7. Ursem, N. T. C., Brinkman, H. J. F., Struijk, P. C., Hop, W. C. J., Kempski, M. H., Keller, B. B. and Wladimiroff, J. W. (1998) Umbilical artery waveform analysis based on maximum, mean and mode velocity in early human pregnancy. Ultrasound Med. Biol. 24, 1-7
8. Kempski, M. H. (1995) Modeling and control of embryonic hemodynamics. In Developmental Mechanisms of Heart Disease (Clark, E. B., Markwald, R. R. and Takao, A., eds.), pp. 421-34, Futura Publishing Co., Armonk, NY
9. Kloosterman, G. (1970) On intrauterine growth. Int. J. Obstet. Gynaecol. 8, 895-912
10. Ide, M. (1989) Acoustic data of Japanese ultrasonic diagnostic equipment. Ultrasound Med. Biol. 15, 49-53
11. Hoskins, P. R., Loupas, T. and McDicken, W. N. (1991) An investigation of simulated umbilical artery Doppler waveforms. I. The effect of three physical parameters on the maximum frequency envelope and on pulsatility index. Ultrasound Med. Biol. 17, 7-21
12. Neter, J. and Wasserman, W. (1974) Applied Linear Statistical Models, R. D. Irwin Inc., Chicago
13. Robinson, H. P. and Shaw-Dunn, J. (1973) Fetal heart rates as determined by sonar in early pregnancy. J. Obstet. Gynaecol. Br. Commonw. 80, 805-809
14. Martinez, J. M., Comas, C., Ojuel, J., Borrell, A., Puerto, B. and Fortuny, A. (1996) Fetal heart rate patterns in pregnancies with chromosomal disorders or subsequent fetal loss. Obstet. Gynecol. 87, 118-121
15. Jauniaux, E., Jurkovic, D. and Campbell, S. (1991) In vivo investigations of the anatomy and the physiology of early human placental ciculations. Ultrasound Obstet. Gynecol. 1, 435-445
16. Reference deleted.
17. Kenny, J., Plappert, T., Doubilet, P., Salzman, D. and St. John Sutton, M. G. (1987) Effects of heart rate on ventricular size, stroke volume, and output in the normal human fetus: a prospective Doppler echocardiographic study. Circulation 76, 52-58
18. Kirkpatrick, S. E., Pitlick, P. T., Naliboff, J. and Friedman, W. F. (1976) Frank-Starling relationship as an important determinant of fetal cardiac output. Am. J. Physiol. 231, 495-500
19. Wagman, A. J., Hu, N. and Clark, E. B. (1990) Effect of changes in circulating blood volume on cardiac output and arterial and ventricular blood pressure in the stage 18, 24 and 29 chick embryo. Circ. Res. 67, 187-192
20. Kempski, M. H., Kibler, N., Blackburn, J. L., Dzakowic, J., Hu, N. and Clark, E. B. (1993) Hemodynamic regulation in the chick embryo. A.S.M.E. Adv. Bioeng. 24, 119-122
21. Yoshigi, M., Hu, N. and Keller, B. B. (1996) Dorsal aortic impedance in stage 24 chick embryo following acute changes in circulating blood volume. Am. J. Physiol. 270, H1597-H1606
22. Siimes, A. S., Välimäki, I. A. T., Antila, K. J. et al. (1990) Regulation of heart rate variation by the autonomic nervous system in neonatal lambs. Pediatr. Res. 27, 383-391
23. Fleisher, L. A., Dipietro, J. A., Johnson, T. R. and Pincus, S. (1997) Complementary and non-coincident increases in heart rate variability and irregularity during fetal development. Clin. Sci. 92, 345-349
24. Nakanishi, T., Seguchi, M. and Takao, A. (1988) Development of the myocardial contractile system. Experientia 44, 936-944
25. Sissman, N. J. (1970) Developmental landmarks in cardiac morphogenesis: comparative chronology. Am. J. Cardiol. 25, 141-148
26. Ursem, N. T. C., Kempski, M. H., Ridder de, M. A. J., Clark, E. B. and Wladimiroff, J. W. (1998) An estimate of fetal autonomic state by spectral analysis of human umbilical artery flow velocity waveforms. Cardiovasc. Res. 37, 601-605