Maternal-fetal tolerance is maintained despite transgene-driven trophoblast expression of MHC class I, and defects in Fas and its ligand

European Journal of Immunology

Volumn 28, Issue 11, 1998, Pages 3479-3487

  Rogers, Amy M ^a   Boime, Irving ^a   Connolly, Janet ^a   Cook, James R ^a   Russell, John H ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

Fas ligand; MHC class I; Placenta; Tolerance; Trophoblast

Indexed keywords

FAS ANTIGEN; FAS LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FETOPLACENTAL UNIT; FETUS; GIANT CELL; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; MAMMAL; MATERNAL BLOOD; MOUSE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; TROPHOBLAST; UTERUS;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD95; FAS LIGAND PROTEIN; FEMALE; FETUS; H-2 ANTIGENS; IMMUNE TOLERANCE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PREGNANCY; TRANSGENES; TROPHOBLASTS;

EID: 0031770482     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199811)28:11<3479::AID-IMMU3479>3.0.CO;2-U     Document Type: Article

References (32)

1. Medawar, P. B., Some immunological and endocrinological problems raised by the evolution of viviparity in vertebrates. Symp. Soc. Exp. Biol. 1953. 44: 320-338.
2. Seigler, H. F. and Metzgar, R. S., Embryonic development of human transplantation antigens. Transplantation 1970. 9: 478-486.
3. Faulk, W. P. and Temple, A., Distribution of beta2 microglobulin and-HLA in chorionic villi of human placentae. Nature 1976. 262: 799-802.
4. Goodfellow, P. N., Barnstable, C. J., Bodmer, W. F., Snary, D. and Crumpton, M. J., Expression of HLA system antigens on placenta. Transplantation 1976. 22: 595-603.
5. Zuckermann, F. A. and Head, J. R., Expression of MHC antigens on murine trophoblast and their modulation by Interferon. J. Immunol. 1986. 137: 846-853.
6. Hunt, J. S., Andrews, G. K. and Wood, G. W., Normal trophoblasts resist induction of class I HLA. J. Immunol. 1987. 138: 2481-2487.
7. Hunt, J. S., Fishback, J. L., Andrews, G. K. and Wood, G. W., Expression of class I HLA genes by trophoblast cells. Analysis by in situ hybridization. J. Immunol. 1988. 140: 1293-1299.
8. Redline, R. W. and Lu, C. Y., Localization of fetal major histocompatibility complex antigens and maternal leukocytes in murine placenta. Implications for maternal-fetal immunological relationship. Lab. Invest. 1989. 61: 27-36.
9. Kovats, S., Main, E. K., Librach, C., Stubblebine, M., Fisher, S. J. and DeMars, R., A class I antigen, HLA-G, expressed in human trophoblasts. Science 1990. 248: 220-223.
10. Shida, M. M., Jackson-Grusby, L. L., Ross, S. R. and Linzer, D. I., Placental-specific expression from the mouse placental lactogen II gene promoter. Proc. Natl. Acad. Sci. USA 1992. 89: 3864-3868.
11. Bellgrau, D., Gold, D., Selawry, H., Moore, J., Franzusoff, A. and Duke, R. C., A role for CD95 ligand in preventing graft rejection [see comments]. Nature 1995. 377: 630-632.
12. Griffith, T. S., Brunner, T., Fletcher, S. M., Green, D. R. and Ferguson, T. A., Fas ligand-induced apoptosis as a mechanism of immune privilege [see comments]. Science 1995. 270: 1189-1192.
13. Hunt, J. S., Vassmer, D., Ferguson, T. A. and Miller, L., Fas ligand is positioned in mouse uterus and placenta to prevent trafficking of activated leukocytes between the mother and the conceptus. J. Immunol. 1997. 158: 4122-4128.
14. Jiang, S.-P. and Vacchio, M. S., Multiple mechanisms of peripheral T cell tolerance to the fetal allograft. J. Immunol. 1998. 160: 3086-3090.
15. Matiba, B., Mariani, S. M. and Krammer, P. H., The CD95 system and the death of a lymphocyte. Semin. Immunol. 1997. 9: 59-68.
16. Hall, J. and Talamantes, F., Immunocytochemical localization of mouse placental lactogen in the mouse placenta. J. Histochem. Cytochem. 1984. 32: 379-382.
17. Soares, M. J., Colosi, P. and Talamantes, F., The development and characterization of a homologous radioimmunoassay for mouse placental lactogen. Endocrinology 1982. 110: 668-670.
18. Jaffe, L., Robertson, E. J. and Bikoff, E. K., Distinct patterns of expression of MHC class I and beta 2-microglobulin transcripts at early stages of mouse development. J. Immunol. 1991. 147: 2740-2749.
19. Cook, J. R., Wormstall, E. M., Hornell, T., Russell, J., Connolly, J. M. and Hansen, T. H., Quantitation of the Cell Surface Level of L-D Resulting in Positive Versus Negative Selection of the 2c Transgenic T Cell Receptor in Vivo. Immunity 1997. 7: 233-241.
20. Fields, L. E. and Loh, D. Y., Organ injury associated with extrathymic induction of immune tolerance in doubly transgenic mice. Proc. Natl. Acad. Sci. USA 1992. 89: 5730-5734.
21. Tafuri, A., Alferink, J., Moller, P., Hämmerling, G. J. and Arnold, B., T cell awareness of paternal alloantigens during pregnancy. Science 1995. 270: 630-633.
22. Bonney, E. A. and Matzinger, P., The maternal immune system's interaction with circulating fetal cells. J. Immunol. 1997. 158: 40-47.
23. Shinomiya, N., Tsuru, S., Taniguchi, M., Fujisawa, H., Ikeda, M., Zinnaka, Y. and Nomoto, K., Immune protective mechanisms during pregnancy. I. Cell-mediated immunity against Listeria monocytogenes in pregnant mice. Immunology 1986. 59: 373-378.
24. Redline, R. W. and Lu, C. Y., Specific defects in the antilisterial immune response in discrete regions of the murine uterus and placenta account for susceptibility to infection. J. Immunol. 1988. 140: 3947-3955.
25. Wegmann, T. G., Lin, H., Guilbert, L. and Mosmann, T. R., Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon? [see comments]. Immunol. Today 1993. 14: 353-356.
26. Raghupathy, R., Th1-type immunity is incompatible with successful pregnancy. Immunol. Today 1997. 18: 478-482.
27. Runic, R., Lockwood, C. J., Ma, Y., Dipasquale, B. and Guller, S., Expression of Fas ligand by human cytotrophoblasts: implications in placentation and fetal survival. J. Clin. Endocrinol. Metab. 1996. 81: 3119-3122.
28. Hansen, T. H. and Sachs, D. H., Isolation and antigenic characterization of the product of a third polymorphic H-2 locus, H-2L. J. Immunol. 1978. 121: 1469-1472.
29. Sha, W. C., Nelson, C. A., Newberry, R. D., Kranz, D. M., Russell, J. H. and Loh, D. Y., Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice. Nature 1988. 335: 271-274.
30. Kranz, D. M., Sherman, D. H., Sitkovsky, M. V., Pasternack, M. S. and Eisen, H. N., Immunoprecipitation of cell surface structures of cloned cytotoxic T lymphocytes by clone-specific antisera. Proc. Natl. Acad. Sci. USA 1984. 81: 573-577.
31. Lie, W. R., Myers, N. B., Connolly, J. M., Gorka, J., Lee, D. R. and Hansen, T. H., The specific binding of peptide ligand to Ld class I major histocompatibility complex molecules determines their antigenic structure. J. Exp. Med. 1991. 173: 449-459.
32. Sha, W. C., Nelson, C. A., Newberry, R. D., Kranz, D. M., Russell, J. H. and Loh, D. Y., Positive and negative selection of an antigen receptor on T cells in transgenic mice. Nature 1988. 336: 73-76.