The effects of upper respiratory infection on T-cell proliferation and steroid sensitivity of asthmatics

Journal of Allergy and Clinical Immunology

Volumn 102, Issue 4 II, 1998, Pages 592-597

  Vianna, Elcio O ^a   Westcott, Jay ^a   Martin, Richard J ^a  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

Asthma; Common cold; Glucocorticoid; Phytohemagglutinin; T lymphocytes

Indexed keywords

DEXAMETHASONE; GAMMA INTERFERON; HYDROCORTISONE; INTERLEUKIN 10; INTERLEUKIN 8; PHYTOHEMAGGLUTININ; STEROID; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; ASTHMA; CLINICAL ARTICLE; COMMON COLD; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG SENSITIVITY; FEMALE; HUMAN; HUMAN CELL; INHALATIONAL DRUG ADMINISTRATION; LUNG FUNCTION; LYMPHOCYTE PROLIFERATION; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; T LYMPHOCYTE; UPPER RESPIRATORY TRACT INFECTION;

ADULT; ASTHMA; CELL DIVISION; CELLS, CULTURED; DEXAMETHASONE; FEMALE; HUMANS; HYDROCORTISONE; INTERFERON TYPE II; INTERLEUKIN-10; LYMPHOCYTE ACTIVATION; MALE; PHYTOHEMAGGLUTININS; RESPIRATORY TRACT INFECTIONS; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031769257     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0091-6749(98)70274-x     Document Type: Article

References (26)

1. Pattemore PK, Johnston SL, Bardin PG. Viruses as precipitants of asthma symptoms: I. Epidemiology. Clin Exp Allergy 1992;22:325-36.
2. Nicholson KG, Kent J, Ireland DC. Respiratory viruses and exacerbations of asthma in adults. BMJ 1993;307:982-6.
3. Cheung D, Dick EC, Timmers MC, Klerk EPA, Spaan WJM, Sterk PJ. Rhinovirus inhalation causes long-lasting excessive airway narrowing in response to methacholine in asthmatic subject In Vivo. Am J Respir Crit Care Med 1995;152:1490-6.
4. Lemanske RE Jr, Dick EC, Swanson CA, Vrtis RE, Busse WW. Rhinovirus upper respiratory infection increases airway hyperreactivity and late asthmatic reactions. J Clin Invest 1989;83:1-10.
5. Busse WW. The role of respiratory infections in airway hyperresponsiveness and asthma. Am J Respir Crit Care Med 1994;150:S77-9.
6. Calhoun WJ, Dick EC, Schwartz LB, Busse WW. A common cold virus, rhinovirus 16, potentiates airway inflammation after segmental antigen bronchoprovocation in allergic subjects. J Clin Invest 1994;94:2200-8.
7. Gern JE, Busse WW. The effects of rhinovirus infections on allergic airway responses. Am J Respir Crit Care Med 1995;152:S40-5.
8. Szefler SJ, Leung DYM. Glucocorticoid-resistant asthma: pathogenesis and clinical implications for management. Eur Respir J 1997;10:1640-7.
9. Vianna EO, Leung DYM, Georges G, Martin RJ, Kraft M. Responsiveness of lymphocytes to glucocorticoids is decreased in nocturnal asthma [Abstract]. Am J Respir Crit Care Med 1997;155:A887.
10. ACCP-ATS Joint Committee on Pulmonary Nomenclature. Pulmonary terms and symbols. Chest 1975;67:583-93.
11. Snedecor GW, Cochran WG. Statistical methods, 8th ed. Ames, IA: Iowa State University Press; 1989.
12. Virchow JC, Oehling A, Boer L, Hansel TT, Werner P, Matthys H, et al. Pulmonary function, activated T cell, peripheral blood eosinophilia, and serum activity for eosinophil survival in vitro: a longitudinal study in bronchial asthma. J Allergy Clin Immunol 1994;94:240-9.
13. Doi S, Murayama N, Inoue T, Takamatsu I, Kameda M, Omoto Y, et al. CD4 T-lymphocyte activation is associated with peak expiratory flow variability in childhood asthma. J Allergy Clin Immunol 1996;97:955-62.
14. Majori M, Piccoli ML, Bertacco S, Cuomo A, Cantini L, Pesci A. Inhaled beclomethasone dipropionate downregulates CD4 and CD8 T-lymphocyte activation in peripheral blood of patients with asthma. J Allergy Clin Immunol 1997;100:379-82.
15. Alvarez J, Surs W, Leung DYM, Iklé D, Gelfand EW, Szefler SJ. Steroid-resistant asthma: immunologic and pharmacologic features. J Allergy Clin Immunol 1992;89:714-21.
16. Haczku A, Alexander A, Brown P, Assoufi B, Li B, Kay AB, et al. The effect of dexamethasone, cyclosporine, and rapamycin on T-lymphocyte proliferation in vitro: comparison of cells from patients with glucocorticoid-sensitive and glucocorticoid-resistant chronic asthma. J Allergy Clin Immunol 1994;93:510-3.
17. Corrigan CJ, Bungre JK, Assoufi B, Cooper AE, Seddon H, Kay AB. Glucocorticoid resistant asthma: T-lymphocyte steroid metabolism and sensitivity to glucocorticoids and immunosuppressive agents. Eur Respir J 1996;9:2077-86.
18. Spahn JD, Landwehr LP, Nimmagadda S, Surs W, Leung DY, Szefler SJ. Effects of glucocorticoids on lymphocyte activation in patients with steroid-sensitive and steroidresistant asthma. J Allergy Clin Immunol 1996;98:1073-9.
19. Kam JC, Szefler SJ, Surs W, Sher ER, Leung DYM. Combination IL-2 and IL-4 reduces glucocorticoid receptor-binding affinity and T cell response to glucocorticoids. J Immunol 1993;151:3460-6.
20. Sher ER, Leung DYM, Surs W, Kam JC, Zeig G, Kamada AK, et al. Steroid-resistant asthma: cellular mechanisms contributing to inadequate response to glucocorticoid therapy. J Clin Invest 1994;93:33-9.
21. Nimmagadda SR, Szefler SJ, Spahn JD, Surs W, Leung DYM. Allergen exposure decreases glucocorticoid receptor binding affinity and steroid responsiveness in atopic asthmatics. Am J Respir Crit Care Med 1997;155:87-93.
22. Adcock IM, Shirasaki H, Gelder CM, Peters MJ, Brown CR, Barnes PJ. The effects of glucocorticoids on phorbol ester and cytokine stimulated transcription factor activation in human lung. Life Sci 1994;55:1147-53.
23. Adcock IM, Lane SJ, Brown CR, Peters MJ, Lee TH, Barnes PJ. Differences in binding of glucocorticoid receptor to DNA in steroid-resistant asthma. J Immunol 1995;154:3500-5.
24. Barnes PJ, Adcock IM. Steroid resistance in asthma. Q J Med 1995;88:455-68.
25. H2 lymphocytes: doubt some more. J Allergy Clin Immunol 1997;99:161-4.
26. Román M, Calhoun WJ, Hinton KL, Avendaño LF, Simon V, Escobar AM, et al. Respiratory syncytial virus infection in infants is associated with predominant Th-2-like response. Am J Respir Crit Care Med 1997;156:190-5.