Overcoming the histocompatibility barrier: Transferrins as carriers and modulators of immunogenic identity

Cell Transplantation

Volumn 7, Issue 6, 1998, Pages 541-548

  Pierpaoli, Walter ^a,b  

^a Jean Choay Institute for Biomedical Research   (Switzerland)

^b Cellena Inc   (Switzerland)

Author keywords

Tolerance; Transferrin; Transplantation; Xenogeneic

Indexed keywords

GLYCOPROTEIN; TRANSFERRIN;

ALLOTYPE; BONE MARROW; BONE MARROW TRANSPLANTATION; CHIMERA; HISTOCOMPATIBILITY; IMMUNE SYSTEM; IMMUNOLOGICAL TOLERANCE; IRRADIATION; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL; REVIEW; TRANSPLANTATION; XENOGRAFT; XENOTRANSPLANTATION;

EID: 0031767966     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0963-6897(98)00039-6     Document Type: Article

References (62)

1. Aguas, A.P.; Esaguy, N.; Sunkel, C.E.; Silva, M.T. Cross-reactivity and sequence homology between the 65-kilodalton mycobacterial heat shock protein and human lactoferrin, transferrin and DR subsets of major histocompatibility complex Class II molecules. Infect. Immun. 58:1461-1470; 1990.
2. Ashman, R.F. B lymphocyte activation: The transferrin receptor as a prototype intermediate activation molecule. J. Lab. Clin. Med. 116:759-765; 1990.
3. Ball, E.D.; Vredenburgh, J.J.; Mills, L.E.; Comwell, G.G., III, Schwarz, L.; Howell, A.L.; Troy, K. Autologous bone marrow transplantation for acute myeloid leukemia following in vitro treatment with neuraminidase and monoclonal antibodies. Bone Marrow Transplant. 6:277-280; 1990.
4. Beckman, G.; Beckman, L. Decrease of transferrin C2 frequency with age. Hum. Hered. 36:254-255; 1986.
5. Beckman, G.; Beckman, L.; Sikstroem, C. Transferrin C subtypes in different ethnic groups. Hereditas 92:189-192; 1980.
6. Beckman, G.; Beckman, L.; Sikstroem, C. Transferrin C subtypes and spontaneous abortion. Hum. Hered. 30:316-319; 1980.
7. Birgens, H.S. The biological significance of lactoferrin in haematology. Scand. J. Haematol. 33:225-230; 1984.
8. Birgens, H.S.; Hansen, N.E.; Karle, H.; Kristensen, L.O. Receptor binding of lactoferrin by human monocytes. Br. J. Haematol. 54:383-391; 1983.
9. Brock, J.H.; Mainou-Fowler, T. The role of iron and transferrin in lymphocyte transformation. Immunol. Today 4:347-351; 1983.
10. Broxmeyer, H.E. Lactoferrin acts on la-like antigen-positive subpopulations of human monocytes to inhibit production of colony stimulatory activity in vitro. J. Clin. Invest. 64:1717-1720; 1979.
11. Cano, E.; Pizarro, A.; Redondo, J.M.; Sanchez-Madrid, F.; Bernabeu, C.; Fresno, M. Induction of T cell activation by monoclonal antibodies specific for the transferrin receptor. Eur. J. Immunol. 20:765-770; 1990.
12. Deeg, H.J.; Pierpaoli, W.; Arrighi, S.; Kristy, S.; Graham, T.; Huss, R.; Yu, C.; Myerson, D.; Schuening, F.; Storb, R. Facilitation of DLA-incompatible marrow grafts by donorspecific serum transferrin? Transplant. Immunol. 4:113-116; 1996.
13. De Jong, G.; Van Dijk, J.P.; Van Eijk, H.G. The biology of transferrin. Clin. Chim. Acta 190:1-46; 1990.
14. De Sousa, M.; Breedvelt, F.; Dysenius-Trentham, R.; Trentham, D.; Lum, J. Iron, iron-binding proteins and immune system cells. Ann. NY Acad. Sci. 526:310-322; 1988.
15. Donaldson, A.B.P.; Grigor, M.R. Charge forms of serum and whey transferrin in rat differ in the sialic acid content of their glycan chains: Immunological implications. Biochem. Int. 23:525-532; 1991.
16. Duncan, R.L., Jr.; McArthur, W.P. Lactoferrin-mediated modulation of mononuclear cell activities. Cell. Immunol. 63:308-320; 1981.
17. Gentile, P.; Broxmeyer, H.E. Suppression of mouse myelopoiesis by administration of human lactoferrin in vivo and the comparative action of human transferrin. Blood 61:982-993; 1983.
18. Hamilton, T.A.; Weiel, J.E.; Adams, D.O. Expression of the transferrin receptor in murine peritoneal macrophages is modulated in the different stages of activation. J. Immunol. 132:2285-2290; 1984.
19. Hirata, T.; Bitterman, P.B.; Mornex, J.F.; Crystal, R.G. Expression of the transferrin receptor gene during the process of mononuclear phagocyte maturation. J. Immunol. 136:1339-1345; 1986.
20. Huebers, H.A.; Finch, C.A. The physiology of transferrin and transferrin receptors. Physiol. Rev. 67:520-582; 1987.
21. Ieki, R.; Kudoh, S.; Kimura, H.; Ozawa, K.; Asano, S.; Takaku, F. Human granulocyte colony formation in serum-free cultures stimulated with purified recombinant granulocyte colony-stimulating factor. Exp. Hematol. 18:883-887; 1990.
22. Kamboh, M.I.; Ferrell, R.E. Human transferrin polymorphism. Hum. Hered. 37:65-81; 1987.
23. Keown, P.A.; Descamps, B. Improved renal allograft survival after blood transfusion: A non-specific, erythrocyte-mediated immunoregulatory process? Lancet 1:20-22; 1979.
24. Keyna, U.; Nuesslein, I.; Rohwer, P.; Kalden, J.R.; Manger, B. The role of the transferrin receptor for the activation of human lymphocytes. Cell. Immunol. 132:411-422; 1991.
25. Kroemer, G.; Martinez, C. The fail-safe paradigm of immunological self-tolerance. Lancet 338:1246-1249; 1991.
26. Lum, J.B.; Infante, A.J.; Makker, D.M.; Yang, R; Bowman, B.H. Transferrin synthesis by inducer T lymphocytes. J. Clin. Invest. 77:841-849; 1986.
27. b). Immunology 46:253-260; 1982.
28. McGillivray, R.T.A.; Mendez, E.; Shevale, J.G.; Sinha, S.K.; Lineback-Zins, J.; Brew, K. The primary structure of human serum transferrin. J. Biol. Chem. 258:3543-3553; 1983.
29. McGregor, S.J.; Brock, J.H.; Briggs, J.D.; Junor, B.J.R. Release of hydrogen peroxide and expression of HLA-DR and transferrin receptors by monocytes and peritoneal macrophages from patients undergoing continuous ambulatory peritoneal dialysis and normal controls. Clin. Immunol. Immunopathol. 56:151-158; 1990.
30. Mooney, M.L.; Carlson, P.; Hastillo, A.; Szentpetery, S.; Duma, R.J.; Markowitz, S.M. Transferrin receptors and CD4/CD8 lymphocyte ratios in rejection and infection in cardiac transplantation recipients. Transplant. Proc. 22: 2389-2393; 1990.
31. Morishita, Y.; Kataoka, T.; Towatari, M.; Ito, T.; Inoue, H.; Ogura, M.; Morishima, Y.; Saito, H. Up-regulation of transferrin receptor gene expression by granulocyte colony-stimulating factor in human myeloid leukemia cells. Cancer Res. 50:7955-7961; 1990.
32. Nakanaga, M.; Yasuda, T.; Tenjo, E.; Nadano, D.; Fujiki, N.; Kishi, K. Transferrin polymorphisms in Japanese populations: North-south cline in the distribution of the TF*C2 allele. Hum. Biol. 63:187-195; 1991.
33. Niaudet, P. Immunological factors in organ transplantation. Intensive Care Med. 15:61-63; 1989.
34. Novogrodsky, A.; Suthanthiran, M.; Stenzel, K.H. Ferromitogens: Iron-containing compounds with lymphocyte-stimulatory properties. Cell. Immunol. 133:295-305; 1991.
35. Opelz, G.; Sengar, D.P.S.; Mickey, M.R.; Terasaki, P.I. Effect of blood transfusions on subsequent kidney transplants. Transplant. Proc. 5:253-258; 1973.
36. Peters, T.J.; Raja, K.B.; Simpson, R.J.; Snape, S. Mechanisms and regulation of intestinal Iron absorption. Ann. NY Acad. Sci. 526:141-147; 1988.
37. Pierpaoli, W. Integrated phylogenetic and ontogenetic evolution of neuroendocrine and identity-defense, immune functions. In: Ader, R., ed. Psychoneuroimmunology. New York, Academic Press; 1981:575-606.
38. Pierpaoli, W. The bone marrow, our autonomous "morphostatic brain." In: Volume 2: Breakdown in human adaptation to stress: Towards a multidisciplinary approach. The Hague, Holland: Martinus Nijhoff Publishers; 1984: 713-721.
39. Pierpaoli, W. Immunoregulatory and morphostatic function of bone marrow-derived factors. In: Guillemin, R.; Cohn, M.; Melnechuk, T., eds. Neural modulation of immunity. New York; Raven Press; 1985:205-220.
40. Pierpaoli, W. Growth of transplantable melanoma and leukemia and prevention of virus-induced leukemia in long-lived radiation chimeras constructed with unmanipulated bone Marrow. Clin. Exp. Immunol. 59:210-216; 1985.
41. Pierpaoli, W. Effect of human transferrin on the engraftment of allogeneic bone marrow in various strains of lethally irradiated mice. Nat. Immun. 11:356-365; 1992.
42. Pierpaoli, W.; Balakrishnan, J.; Maestroni, G.; Sache, E.; Choay, J. Bone marrow: A "morphostatic brain" for control of normal and neoplastic growth. Experimental evidence. Ann. NY Acad. Sci. 521:300-311; 1988.
43. Pierpaoli, W.; Dall'Ara, A.; Yi, C.X.; Neri, P.; Santucci, A.; Choay, J. Iron carrier proteins facilitate engraftment of allogeneic bone marrow and enduring hemopoietic chimerism in the lethally irradiated host. Cell. Immunol. 134:225-234; 1991.
44. Pierpaoli, W.; Kellerhals, R.; Buehler, A.; Sache, E. Experimental manipulations and bone marrow-derived factors which affect the outcome of bone marrow transplantation across the H-2 barrier in lethally irradiated mice. J. Clin. Lab. Immunol. 16:115-124; 1985.
45. Pierpaoli, W.; Lesnikov, V.A.; Lesnikova, M.P.; Arrighi, S.; Bardotti, A. Specific xenogeneic (human) tolerance in immunosuppressed mice by combined donor-derived human transferrin and antigens. Transplant. Proc. 28:711-712; 1996.
46. Pierpaoli, W.; Lesnikov, V.A.; Lesnikova, M.P.; Arrighi, S. Donor-derived plasma transferrin facilitates the engraftment of xenogeneic (rat) bone marrow in irradiated mice. Bone Marrow Transplant. 18:203-207; 1996.
47. Pierpaoli, W.; Lesnikov, V.A.; Lesnikova, M.; Arrighi, S.; Bardotti, A. Unresponsiveness to human leukocytes in immunosuppressed mice by combined donor-derived human transferrin and antigens. Transplant Immunol. 4:301-308; 1996.
48. Pierpaoli, W.; Maestroni, G. Drug-induced chimerism and prevention of graft versus-host disease in lethally irradiated mice transplanted with rat bone marrow. Transplantation 26:456-458; 1978.
49. Pierpaoli, W.; Maestroni, G. A new pre-irradiation conditioning regimen which protects against radiation injury and facilitates engraftment of xenogeneic bone marrow. Scand. J. Haematol. 22:165-172; 1979.
50. Pierpaoli, W.; Maestroni, G. Facilitation of enduring engraftment of homologous bone marrow and avoidance of secondary disease in mice. Cell. Immunol. 52:62-72; 1980.
51. Pierpaoli, W.; Maestroni, G. Induction of enduring allogeneic chimerism in rabbits via soluble marrow-derived components. Immunol. Lett. 1:255-258; 1980.
52. Pierpaoli, W.; Maestroni, G. Dominance and persistence of donor marrow in long-lived allogeneic radiation chimeras with unmanipulated bone marrow. Immunol. Lett. 6:197-202; 1983.
53. Pierpaoli, W.; Maestroni, G.; Sache, E. Enduring allogeneic marrow engraftment via non-specific bone marrow-derived regulating factors (MRF). Cell. Immunol. 57:219-228; 1981.
54. Samlowski, W.E.; Daynes, R.A. Bone marrow engraftment efficiency is enhanced by competitive inhibition of the hepatic asialoglycoprotein receptor. Proc. Natl. Acad. Sci. USA 82:2508-2512; 1985.
55. Sieff, C.A. Membrane antigen expression during hemopoietic differentiation. CRC Crit. Rev. Oncol. Hematol. 5:1-36; 1986.
56. Taetle, R.; Honeysett, J.M. γ-Interferon modulates human monocyte/macrophage transferrin receptor expression. Blood 71:1590-1595; 1988.
57. Takahashi, S.; Esserman, L.; Levy, R. An epitope on the transferrin receptor preferentially exposed during tumor progression in human lymphoma is close to the ligand binding site. Blood 77:826-832; 1991.
58. Thorson, J.A.; Smith, K.M.; Gomez, F.; Nauman, P.W.; Kemp, J.D. Role of iron in T cell activation: TH1 clones differ from the TH2 clones in their sensitivity to inhibition of DNA synthesis caused by IGG Mabs against the transferrin receptor and the iron chelator deferoxamine. Cell. Immunol. 134:126-137; 1991.
59. Titenko, N.V.; Spitsyn, V.A.; Alekseeva, T.I. Transferrin types in different ethnic groups of the USSR and Mongolia. Hum. Hered. 41:201-205; 1991.
60. Woodward, J.E.; Bayer, A.L.; Chavin, K.D.; Boleza, K.A.; Baliga, P. Anti-transferrin receptor monoclonal antibody. A novel immunosuppressant. Transplantation 65:6-9; 1998.
61. Zinkernagel, R.M. Thymus and lymphohemopoietic cells: Their role in T cell maturation in selection of T cells' H-2-restriction-specificity and in H-2 linked Ir gene control. Immunol. Rev. 42:224-270; 1978.
62. Zinkernagel, R.M.; Moskophidis, D.; Kuendig, T.; Oehen, S.; Pircher, H.; Hengartner, H. Effector T-cell induction and T-cell memory versus peripheral deletion of T cells. Immunol. Rev. 131:199-223; 1993.