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Volumn 26, Issue 6, 1998, Pages 562-565

Analysis of metabolite formation pharmacokinetics after intravenous and oral administration of the parent drug using inverse Laplace transformation

Author keywords

[No Author keywords available]

Indexed keywords

DRUG; DRUG METABOLITE;

EID: 0031767963     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (7)

References (11)
  • 1
    • 0025246336 scopus 로고
    • Effects of first-pass metabolism on metabolite mean residence time determination after oral administration of parent drug
    • Chan KKH and Gibaldi M (1990) Effects of first-pass metabolism on metabolite mean residence time determination after oral administration of parent drug. Pharm Res 7:59-63.
    • (1990) Pharm Res , vol.7 , pp. 59-63
    • Chan, K.K.H.1    Gibaldi, M.2
  • 2
    • 0027460865 scopus 로고
    • Morphine pharmacokinetics and metabolism in humans: Enterohepatic cycling and relative contribution of metabolites to active opioid concentrations
    • Hasselström J and Säwe J (1993) Morphine pharmacokinetics and metabolism in humans: enterohepatic cycling and relative contribution of metabolites to active opioid concentrations. Clin Pharmacokinet 24:344-354.
    • (1993) Clin Pharmacokinet , vol.24 , pp. 344-354
    • Hasselström, J.1    Säwe, J.2
  • 3
    • 0023761488 scopus 로고
    • Metabolite formation pharmacokinetics: Rate and extent of metabolite formation determined by deconvolution
    • Karol MD and Goodrich S (1988) Metabolite formation pharmacokinetics: rate and extent of metabolite formation determined by deconvolution. Pharm Res 5:347-351.
    • (1988) Pharm Res , vol.5 , pp. 347-351
    • Karol, M.D.1    Goodrich, S.2
  • 4
    • 0031869375 scopus 로고    scopus 로고
    • Pharmacokinetics of morphine-6-glucuronide and its formation from morphine following i.v.-administration
    • in press
    • Lötsch J, Weiss M, Kobal G and Geisslinger G (1998) Pharmacokinetics of morphine-6-glucuronide and its formation from morphine following i.v.-administration. Clin Pharmacol Ther, in press.
    • (1998) Clin Pharmacol Ther
    • Lötsch, J.1    Weiss, M.2    Kobal, G.3    Geisslinger, G.4
  • 5
    • 0026515132 scopus 로고
    • Pharmacokinetic modelling of a parent drug and its metabolite atracurium and laudanosine
    • Nigrovic V and Banoub M (1992) Pharmacokinetic modelling of a parent drug and its metabolite atracurium and laudanosine. Clin Pharmacokinet 22:396-408.
    • (1992) Clin Pharmacokinet , vol.22 , pp. 396-408
    • Nigrovic, V.1    Banoub, M.2
  • 6
    • 0029609636 scopus 로고
    • Accuracy of numerical inversion of Laplace transforms for pharmacokinetic parameter estimation
    • Purves RD (1995) Accuracy of numerical inversion of Laplace transforms for pharmacokinetic parameter estimation. J Pharm Sci 84:71-74.
    • (1995) J Pharm Sci , vol.84 , pp. 71-74
    • Purves, R.D.1
  • 8
    • 0023836602 scopus 로고
    • A general model of metabolite kinetics following intravenous and oral administration of the parent drug
    • Weiss M (1988) A general model of metabolite kinetics following intravenous and oral administration of the parent drug. Biopharm & Drug Dispos 9:159-176.
    • (1988) Biopharm & Drug Dispos , vol.9 , pp. 159-176
    • Weiss, M.1
  • 9
    • 0025246149 scopus 로고
    • Use of metabolite AUC data in bioavailability studies to discriminate between absorption and first-pass extraction
    • Weiss M (1990) Use of metabolite AUC data in bioavailability studies to discriminate between absorption and first-pass extraction. Clin Pharmacokinet 18:419-422.
    • (1990) Clin Pharmacokinet , vol.18 , pp. 419-422
    • Weiss, M.1
  • 10
    • 0029973918 scopus 로고    scopus 로고
    • A novel extravascular input function for the assessment of drug absorption in bioavailability studies
    • Weiss M (1996) A novel extravascular input function for the assessment of drug absorption in bioavailability studies. Pharm Res 13:1547-1553.
    • (1996) Pharm Res , vol.13 , pp. 1547-1553
    • Weiss, M.1
  • 11
    • 0018715566 scopus 로고
    • Pharmacokinetic model based on circulatory transport
    • Weiss M and Förster W (1979) Pharmacokinetic model based on circulatory transport. Eur J Clin Pharmacol 16:287-293.
    • (1979) Eur J Clin Pharmacol , vol.16 , pp. 287-293
    • Weiss, M.1    Förster, W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.