Pharmacological modulation of GABA(A) receptor-mediated postsynaptic potentials in the CA1 region of the rat hippocampus

British Journal of Pharmacology

Volumn 125, Issue 7, 1998, Pages 1529-1542

  Manuel, Nicholas A ^a   Davies, Ceri H ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Baclofen; Benzodiazepine; Carbachol; DAGO; GABA(A) receptors; ORG 21465; Propofol; Zinc; Zoplidem

Indexed keywords

2 CHLOROADENOSINE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; ATROPINE; BACLOFEN; BENZYL[3 [[1 (3,4 DICHLOROPHENYL)ETHYL]AMINO] 2 HYDROXYPROPYL]PHOSPHINIC ACID; BICUCULLINE; CARBACHOL; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; FLUNITRAZEPAM; LORECLEZOLE; NALOXONE; NEUROSTEROID; PENTOBARBITAL; PRESYNAPTIC RECEPTOR; PROPOFOL; ZINC; ZOLPIDEM;

4 AMINOBUTYRIC ACID UPTAKE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HIPPOCAMPUS; INTERNEURON; NEWBORN; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; RAT;

EID: 0031767015     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702237     Document Type: Article

References (56)

1. ALGER, B.E. & NICOLL, R.A. (1982a). Feed-forward dendritic inhibition in rat hippocampal pyramidal cells studied in vitro. J. Physiol., 328, 105-123.
2. ALGER, B.E. & NICOLL, R.A. (1982b). Pharmacological evidence for two kinds of GABA receptor on rat hippocampal pyramidal cells studied in vitro. J. Physiol., 328, 125-141.
3. AVOLI, M. & PERREAULT, P. (1987). A GABAergic depolarizing potential in the hippocampus disclosed by the convulsant 4-aminopyridine. Brain Res., 400, 191-195.
4. AVOLI, M., BARBAROSIE, M., LÜCKE, A., NAGAO, T., LOPANTSEV, V. & KÖHLING, R. (1996). Synchronous GABA-mediated potentials and epileptiform discharges in the rat limbic system in vitro. J. Neurosci., 16, 3912-3924.
5. A receptors and its applications. In GABA: Receptors, Transporters and Metabolism. Eds. Tanaka C. & Bowery, N.G. pp. 129-143. Basel Switzerland: Birkhäuser Verlag.
6. BEHRENDS J.C. & TEN BRUGGENCATE, G. (1993). Cholinergic modulation of synaptic inhibition in the guinea pig hippocampus in vitro: Excitation of GABAergic interneurons and inhibition of GABA release, J. Neurophysiol., 69, 626-629.
7. BRUSSARD, A.B., KITS, K.S., BAKER, R.E., WILLEMS, W.P.A., LEYTING-VERMEULEN, J.W., VOORN, P., SMIT, A.B., BICK-NELL, R.J. & HERBISON, A.E. (1997). Plasticity in fast synaptic inhibition of adult oxytocin neurons caused by switch in GABAA receptor subunit expression. Neuron, 19, 1103-1114.
8. BUHL, E.H., HALASY, K. & SOMOGYI, P. (1994). Diverse sources of hippocampal unitary inhibitory postsynaptic potentials and the number of synaptic release sites. Nature, 368, 823-828.
9. COHEN, G.A., DOZE, V.A. & MADISON, D.V. (1992). Opioid inhibition of GABA release from presynaptic terminals of rat hippocampal interneurons. Neuron, 9, 325-335.
10. B autoreceptors in rat hippocampus. J. Physiol., 472, 245-265.
11. DAVIES. C.H., DAVIES, S.N. & COLLINGRIDGE, G.L. (1990). Pairedpulse depression of monosynaptic GABA-mediated inhibitory postsynaptic responses in rat hippocampus. J. Physiol., 424, 513-531.
12. DAVIES, P.A., HANNA. M.C., HALES, T.G. & KIRKNESS, E.F. (1997). Insensitivity to anaesthetic agents conferred by a class of GABAA receptor subunit. Nature, 385, 820-823.
13. 2+. Neuron, 5, 781-788.
14. FREUND, T.F. & BUZSÁKI, G. (1996). Interneurons of the hippocampus. Hippocampus. 6, 347-470.
15. A receptor gating kinetics on the a-subunit isoform: implications for structure-function relations and synaptic transmission. J. Physiol., 489, 529-543.
16. A receptor-mediated responses in pyramidal cells of rat hippocampus. J. Neurophysiol., 69, 1541 - 1555.
17. HADINGHAM, K.L., WINGROVE, P.B., WAFFORD, K.A., BAIN, C., KEMP, J.A., PALMER, J.K., WILSON, A.W., WILCOX, A.S., SIKELA, J.M., RAGAN, C.I. & WHITING, P.J. (1993). Role of the β-subunit in determining the pharmacology of human γ-aminobutyric acid type A receptors. Mol. Pharmacol., 44, 1211-1218.
18. HÁJOS, N., PAPP, E.C.S., ACSÁDY, L., LEVEY, A.I. & FREUND, T.F. (1998). Distinct interneuron types express M2 musarinic receptor immunoreactivity on their dendrites or axon terminals in the hippocampus. Neurosci., 82, 355-376.
19. KAILA, K. (1993). Ionic basis of GABAA channel function in the nervous system. Prog. Neurobiol., 42, 489-537.
20. + transient. J. Neurosci., 17, 7662-7672.
21. A receptors. Neuropharmacology, 35, 1289-1298.
22. LAMBERT, J.J., BELELLI, D., HILL-VENNING, C. & PETERS, J.A. (1995). Neurosteroids and GABAA receptor function. TIPS, 16, 295-303.
23. A receptormediated dendritic inhibition in area CA1 of the rat hippocampus. J. Neurophysiol., 66, 1538-1548.
24. LAMBERT, N.A., HARRISON, N.L. & TEYLER, T.J. (1991b). Evidence for mu opiate receptors on inhibitory terminals in area CA1 of rat hippocampus. Neurosci. Lett., 124, 101-104.
25. B receptors. Neurosci. Lett., 135, 215-218.
26. LAMBERT, N.A. & TEYLER, T.J. (1991a). Adenosine depresses excitatory but not fast inhibitory synaptic transmission in area CA1 of the rat hippocampus. Neurosci. Lett., 122, 50-52.
27. LAMBERT, N.A. & TEYLER, T.J. (1991b). Cholincrgic disinhibition in area CA1 of the rat hippocampus is not mediated by receptors located on inhibitory neurons. Eur. J. Pharmacol., 203, 129-131.
28. LAMBERT, N.A. & WILSON, W. A. (1993). Heterogeneity in presynaptic regulation of GABA release from hippocampal inhibitory neurons. Neuron. 11(6), 1057-1067.
29. A receptor channels. Ann. Rev. Neurosci., 17, 569-602.
30. A receptor subtypes immunopurified from rat brain with α subunit-specific antibodies have unique pharmacological properties. Neuron, 7, 667-676.
31. A-rcceptor subtypes really occur in the brain? TINS, 19, 139-143.
32. A receptor-mediated IPSPs in rat hippocampal CA1 pyramidal neurones. Br. J. Pharmacol., 122, 95P.
33. A receptor-mediated IPSPs in rat hippocampal CA1 pyramidal neurones. Br. J. Pharmacol., 122, 342P.
34. A receptors in the hippocampus. Science, 253, 1420-1423.
35. NUSSER, Z., SIEGHART, W., BENKE, D., FRITSCHY, J.-M. & SOMOGYL, P. (1996). Differential synaptic localization of two major γ-aminobutyric acid type A receptor α subunits on hippocampal pyramidal cells. Proc. Natl. Acad. Sci. U.S.A., 93, 11939-11944.
36. A-mediated IPSCs in rat hippocampus. J. Physiol., 484, 425-436.
37. PERKINS, K.L. & WONG, R.K.S. (1996). Ionic basis of the postsynaptic depolarizing GABA response in hippocampal pyramidal cells. J. Neurophysiol., 76, 3886-3894.
38. PERREAULT, P. & AVOLI, M. (1988). A depolarizing inhibitory postsynaptic potential activated by synaptically released GABA under physiological conditions in rat hippocampal pyramidal neurones. Can. J. Physiol. Pharmacol., 66, 1100-1102.
39. A receptor α5-subunit creates novel type II henzodiazepine receptor pharmacology. J. Neurochcm., 54, 1802-1804.
40. ROEPSTORFF, A. & LAMBERT, J.D. (1992). Comparision of the effect of the GABA uptake blockers, tiagabine and nipecotic acid, on inhibitory synaptic efficacy in hippocampal CA1 neurons. Neurasci. Lett., 142, 131-134.
41. ROEPSTORFF, A. & LAMBERT, J.D. (1994). Factors contributing to the decay of stimulus-evoked IPSC in rat hippocampal CA1 neurons. J. Neurophysiol., 72, 2911-2926.
42. A-mediated IPSPs of rat hippocampal neurons. J. Neurophysiol., 70, 1076-1085.
43. A receptor subtypes. Pharmacol. Rev., 47, 181-234.
44. A receptors are differentially sensitive to zinc: dependence on subunit composition, Br. J. Pharmacol., 103, 1837-1839.
45. A receptors. Science. 269, 977-981.
46. A receptors in rat CA1 pyramidal neurons. J. Neurophysiol., 77, 2213-2218.
47. THOMPSON, S.M., CAPOGNA, M. & SCANZIANI, M. (1993). Presynaptic inhibition in the hippocampus. TINS, 16, 222-227.
48. THOMPSON, S.M. & GÁHWILER, B.H. (1992). Effects of the GABA uptake inhibitor tiagabine on inhibitory synaptic potentials in rat hippocampal slice cultures. J. Neurophysiol., 67, 1698-1701.
49. 2 and ββ subunit. Proc Natl. Acad. Sci. U.S.A., 91, 4569-4573.
50. A receptor subunit mRNAs in the rat brain. I. Telencephalon, Diencephalon, Mesencephalon. J. Neurosci., 12, 1040-1062.
51. A receptor channels: from subunits to functional entities. Curr. Opin Neurohiol., 2, 263-269.
52. 4 subunit. FEBS Lett., 289, 227-230.
53. A receptor subunit conferring atypical functional properties. J. Neurosci., 17, 5027-5037.
54. XIE, X. & SMART, T.G. (1993). Properties of GABA-mediated synaptic potentials induced by zinc in adult rat hippocampal pyramidal neurones. J. Physiol., 460, 503-523.
55. A,/benzodiazepine receptors. EMBO J., 9, 3261-3267.
56. A receptors. J. Neurosci., 16, 6648-6656.