Cyclin A and MIB1 (Ki67) as markers of proliferative activity in primary renal neoplasms

Modern Pathology

Volumn 11, Issue 10, 1998, Pages 963-966

  Renshaw, Andrew A ^a   Loughlin, Kevin R ^a   Dutta, Anindya ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Immunohistochemistry; Ki67; Kidney; Proliferation; Renal cell carcinoma; Renal neoplasms

Indexed keywords

CYCLIN A; KI 67 ANTIGEN; MONOCLONAL ANTIBODY KI 67;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER STAGING; CELL PROLIFERATION; CHROMOPHOBE ADENOMA; CLEAR CELL CARCINOMA; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY ADENOMA; KIDNEY CARCINOMA; KIDNEY SARCOMA; KIDNEY TUMOR; MALE; ONCOCYTOMA; PAPILLOMA; PRIORITY JOURNAL;

ADENOMA; ANTIGENS, NUCLEAR; CARCINOMA, RENAL CELL; CELL DIVISION; CYCLIN A; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; KI-67 ANTIGEN; KIDNEY NEOPLASMS; MALE; MIDDLE AGED; MITOTIC INDEX; NEOPLASM STAGING; NUCLEAR PROTEINS; TUMOR MARKERS, BIOLOGICAL;

EID: 0031765635     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Larsson P, Roos G, Stenling R, Ljungberg B. Tumor-cell proliferation and prognosis in renal cell carcinoma. Int J Cancer 1993;55:566-70.
2. Larsson P. Cell proliferation in renal cell carcinoma. Scand J Urol Nephrol Suppl 1994;165:1-48.
3. Delahunt B, Bethwaite PB, Thornton A, Ribas IL. Proliferation of renal cell carcinoma assessed by fixation-resistant polyclonal Ki67 antibody labeling. Cancer 1995;75:2714-9.
4. Tannapfel A, Hahn HA, Katalinic A, Fietkau RJ, Kuhn R, Wittekind CW. Prognostic value of ploidy and proliferation markers in renal cell carcinoma. Cancer 1996;77:164-71.
5. Yokogi H. Flow cytometric quantitation of the proliferation associated nuclear antigen p105 and DNA content in patients with renal cell carcinoma. Cancer 1996;78:819-26.
6. Grignon DJ, Abdel-Malak M, Mertens W, Kostner J, Keeney M, Sakr W, et al. Prognostic significance of cellular proliferation in renal cell carcinoma: a comparison of synthesis-phase fraction and proliferating cell nuclear antigen. Mod Pathol 1995;8:18-24.
7. Hindermann W, Berndt A, Wunderlich H, Katenkamp D, Kosmehl H. Quantitative evaluation of apoptosis and proliferation in renal cell carcinoma. Correlation to tumor sub-type, cytological grade according the thoenes classification and the occurrence of metastasis. Pathol Res Pract 1997;193: 1-7.
8. Haitel A, Wiener HG, Migschitz B, Marberger M, Susani M. Proliferating cell nuclear antigen and MIB1: an alternative to classic prognostic indications in renal cell carcinomas. Am J Clin Pathol 1997;107:229-35.
9. Scheinfeld AG, Campbell S, Gaudin PB, Bryant DA, Reuter VE. Conventional (clear cell) renal cell carcinoma: a clinico-pathologic study of 155 consecutive cases [abstract]. Mod Pathol 1998;11:94A.
10. Dabbs DJ, Davis AT, Bonsib SM, Jones TE. Comparison of MIB1 proliferation rates for eosinophilic tumors: oncocytpmas, chromophobe renal carcinoma, and eosinophilic variant of renal carcinoma (abstract). Mod Pathol 1998;11:79A.
11. Fleming ID, Cooper JS, Henson DE, editors. American Joint Committee on Cancer Cancer Staging Manual. 5th ed. Philadelphia: Lippincott; 1997. p. 231-4.
12. Fuhrman S, Lasky L, Limas C. Prognostic significance of morphologic parameters in renal cell carcinoma. Am J Surg Pathol 1982;6:655-63.
13. Störkel S, Eble JN, Adlakha K, Amin MB, Blute ML, Bostwick DG, et al. Classification of renal cell carcinoma: Workgroup No. 1. Union Internationale Contre le Cancer (UICC) and the American Joint Committee on Cancer (AJCC). Cancer 1997; 80:987-9.
14. Dutta A, Chandra R, Leiter LM, Lester S. Cyclins as markers of tumor proliferation: immunocytochemical studies in breast cancer. Proc Natl Acad Sci U S A 1995;92:5386-90.
15. Mashal RD, Lester S, Corless C, Richie JP, Chandra R, Propert KJ, et al. Expression of cell-cycle proteins in prostate cancer. Cancer Res 1996;56:4159-63.
16. Gerdes J, Schwab U, Lemke H, Stein H. Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int J Cancer 1983; 31:13-20.