Plasmodium falciparum: Modulation by phenobarbital of sensitivity to quinine, chloroquine and mefloquine in vitro

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 92, Issue 5, 1998, Pages 561-562

  Mangou, François ^a   Platel, Denis F ^a   Haumont, Gilbert ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

Chloroquine; Drug resistance; Malaria; Mefloquine; Phenobarbital; Plasmodium falciparum; Quinine

Indexed keywords

ANTICONVULSIVE AGENT; ANTIMALARIAL AGENT; CHLOROQUINE; MEFLOQUINE; PHENOBARBITAL; QUININE;

BRAIN MALARIA; CONTROLLED STUDY; DRUG POTENTIATION; DRUG SENSITIVITY; HEMATOCRIT; MALARIA; NONHUMAN; PLASMODIUM FALCIPARUM; SHORT SURVEY;

CINCHONA PUBESCENS; PLASMODIUM FALCIPARUM;

EID: 0031765529     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0035-9203(98)90915-4     Document Type: Article

References (9)

1. Amabeoku, G. J., Chikuni, O., Akino, C. & Mutetwa, S. (1993). Pharmacokinetic interaction of single doses of quinine and carbamazepine, phenobarbital and phenytoin in healthy volunteers. East African Medical Journal, 70, 90-92.
2. Blanchard, T. J., Mabey, D. C. W., Hunt-Cooke, A., Edwards, G., Hutchinson, D. B. A., Benjamin, S. & Chiodini, P. L. (1994). Multiresistant falciparum malaria cured using atovaquone and proguanil. Transactions of the Royal Society of Tropical Medicine and Hygiene, 88, 693.
3. Desjardins, R. E., Caufield, C. T., Haynes, J. & Chulay, J. D. (1979). Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique. Antimicrobial Agents and Chemotherapy, 16, 710-718.
4. Lebras, J. & Deloron, P. (1983). In vitro study of drug sensitivity of Plasmodium falciparum: evaluation of a new semi-micro test. American Journal of Tropical Medicine and Hygiene, 32, 447-451.
5. Ndifor, A. M., Howells, R. E., Bray, P. G., Ngu, J. L. & Ward, S. A. (1993). Enhancement of drug susceptibility in Plasmodium falciparum in vitro and Plasmodium berghei in vivo by mixed-function oxidase inhibitors. Antimicrobial Agents and Chemotherapy, 37, 1318-1323.
6. Pukrittayakamee, S., Supranaranond, W., Looareesuwan, S., Vanijanonta, S. & White, N. J. (1994). Quinine in severe falciparum malaria: evidence of declining efficacy in Thailand. Transactions of the Royal Society of Tropical Medicine and Hygiene, 88, 324-327.
7. Tish, K. N. (1997). Recrudescence of Plasmodium falciparum malaria contracted in Lombok, Indonesia after quinine/doxycycline and mefloquine: case report. New Zealand Medical Journal, 110, 255-256.
8. Trager, W. & Jensen, J. B. (1976). Human malaria parasites in continuous culture. Science, 193, 673-675.
9. White, N. J., Looareesuwan, S., Phillips, R. E., Chanthavanich, P. & Warrell, D. A. (1988). Single dose phenobarbital prevents convulsions in cerebral malaria. Lancet, ii, 64-66.