The FruA signal transduction protein provides a checkpoint for the temporal co-ordination of intercellular signals in Myxococcus xanthus development

Molecular Microbiology

Volumn 30, Issue 4, 1998, Pages 807-817

  Ellehauge, Eva ^a   Norregaard Madsen, Mads ^a   Søgaard Andersen, Lotte ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; DNA BINDING PROTEIN;

ARTICLE; BACTERIAL GROWTH; DEVELOPMENTAL GENETICS; FRUITING BODY; MYXOCOCCALES; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPOROGENESIS;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BINDING SITES; GENES, BACTERIAL; MOLECULAR SEQUENCE DATA; MYXOCOCCUS XANTHUS; PHOSPHORYLATION; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION; SPORES, BACTERIAL; TRANSCRIPTION FACTORS; TRANSPOSASES;

BACTERIA (MICROORGANISMS); MYXOCOCCALES; MYXOCOCCUS XANTHUS;

EID: 0031765382     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1998.01113.x     Document Type: Article

References (42)

1. Baikalov, I.G., Schröder, I., Kaczor-Grzeskowiak, M., Gunsalus, R.P., and Dickerson, R.E. (1996) Structure of the Escherichia coli response regulator NarL. Biochemistry 35: 11053-11061.
2. Bibb, M.J., Findlay, P.R., and Johnson, M.W. (1984) The relationship between base composition and codon usage in bacterial genes and its use for the simple and reliable identification of protein-coding sequences. Gene 30: 157-166.
3. Domian, I.J., Quon, K.C., and Shapiro, L. (1997) Cell type-specific phosphorylation and proteolysis of a transcriptional regulator controls the G1-to-S transition in a bacterial cell cycle. Cell 90: 415-424.
4. Downard, J., and Toal, D. (1995) Branched-chain fatty acids: the case for a novel form of cell-cell signalling during Myxococcus xanthus development. Mol Microbiol 16: 171-175.
5. Dworkin, M. (1996) Recent advances in the social and developmental biology of the Myxobacteria. Microbiol Rev 60: 70-102.
6. Hagen, D.C., Bretscher, A.P., and Kaiser, D. (1978) Synergism between morphogenetic mutants of Myxococcus xanthus. Dev Biol 64: 284-296.
7. Hagen, T.J., and Shimkets, L.J. (1990) Nucleotide sequence and transcriptional products of the csg locus of Myxococcus xanthus. J Bacteriol 172: 15-23.
8. Hodgkin, J., and Kaiser, D. (1977) Cell-cell stimulation of movement in nonmotile mutants of Myxococcus. Proc Natl Acad Sci USA 74: 2938-2942.
9. Kaiser, D. (1979) Social gliding is correlated with the presence of pili in Myxococcus xanthus. Proc Natl Acad Sci USA 76: 5952-5956.
10. Kashefi, K., and Hartzell, P.L. (1995) Genetic suppression and phenotypic masking of a Myxococcus xanthus frzF defect. Mol Microbiol 15: 483-494.
11. Kim, S.K., and Kaiser, D. (1990a) C-factor: a cell-cell signaling protein required for fruiting body morphogenesis of M. xanthus. Cell 61: 19-26.
12. Kim, S.K., and Kaiser, D. (1990b) Purification and properties of Myxococcus xanthus C-factor, an intercellular signaling protein. Proc Natl Acad Sci USA 87: 3635-3639.
13. Kim, S.K., and Kaiser, D. (1990c) Cell motility is required for the transmission of C-factor, an intercellular signal that coordinates fruiting body morphogenesis of Myxococcus xanthus. Genes Dev 4: 896-904.
14. Kim, S.K., and Kaiser, D. (1990d) Cell alignment required in differentiation of Myxococcus xanthus. Science 249: 926-928.
15. Kim, S.K., and Kaiser, D. (1991) C-factor has distinct aggregation and sporulation thresholds during Myxococcus development. J Bacteriol 173: 1722-1728.
16. Kim, S.K., Kaiser, D., and Kuspa, A. (1992). Control of cell density and pattern by intercellular signaling in Myxococcus development. Annu Rev Microbiol 46: 117-139.
17. Klose, K.E., Weiss, D.S., and Kustu, S. (1993) Glutamate at the site of phosphorylation of nitrogen-regulatory protein NTRC mimics aspartyl-phosphate and activates the protein. J Mol Biol 232: 67-78.
18. Kroos, L., and Kaiser, D. (1987) Expression of many developmentally regulated genes in Myxococcus depends on a sequence of cell interactions. Genes Dev 1: 840-854.
19. Kroos, L., Kuspa, A., and Kaiser, D. (1986) A global analysis of developmentally regulated genes in Myxococcus xanthus. Dev Biol 117: 252-266.
20. Kroos, L., Hartzell, P., Stephens, K., and Kaiser, D. (1988) A link between cell movement and gene expression argues that motility is required for cell-cell signaling during fruiting body development. Genes Dev 2: 1677-1685.
21. Kroos, L., Kuspa, A., and Kaiser, D. (1990) Defects in fruiting body development caused by Tn5 lac insertions in Myxococcus xanthus. J Bacteriol 172: 484-487.
22. Kuspa, A., Kroos, L., and Kaiser, D. (1986) Intercellular signaling is required for developmental gene expression in Myxococcus xanthus. Dev Biol 117: 267-276.
23. Li, S., Lee, B.U., and Shimkets, L.J. (1992) csgA expression entrains Myxococcus xanthus development. Genes Dev 6: 401-410.
24. McCleary, W.R., McBride, M.J., and Zusman, D.R. (1990) Developmental sensory transduction in Myxococcus xanthus involves methylation and demethylation of FrzCD. J Bacteriol 172: 4877-4887.
25. Martinez-Canamero, M., Munoz-Dorado, J., Farez-Vidal, E., lnouye, M., and Inouye, S. (1993) Oar, a 115-kilodalton membrane protein required for development of Myxococcus xanthus. J Bacteriol 175: 4756-4763.
26. Nicholas, K.B., and Nicholas, Jr, H.B. (1997) GENEDOC: a tool for editing and annotating multiple sequence alignments. Distributed by the author.
27. Ogawa, M., Fujitani, S., Mao, X., lnouye, S., and Komano, T. (1996) FruA, a putative transcription factor essential for the development of Myxococcus xanthus. Mol Microbiol 22: 757-767.
28. Parkinson, J.S., and Kofoid, E.C. (1992) Communication modules in bacterial signaling proteins. Annu Rev Genet 26: 71-112.
29. Sager, B., and Kaiser, D. (1994) Intercellular C-signaling and the traveling waves of Myxococcus. Genes Dev 8: 2793-2804.
30. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
31. Shimkets, L.J. (1990) Social and developmental biology of the myxobacteria. Microbiol Rev 54: 473-501.
32. Shimkets, L.J., and Kaiser, D. (1982) Induction of coordinated movement of Myxococcus xanthus cells. J Bacteriol 152: 451-461.
33. Shimkets, L.J., and Rafiee, H. (1990) CsgA, an extracellular protein essential for Myxococcus xanthus development. J Bacteriol 172: 5299-5306.
34. Søgaard-Andersen, L., and Kaiser, D. (1996) C factor, a cell-surface-associated intercellular signaling protein, stimulates the Frz signal transduction system in Myxococcus xanthus. Proc Natl Acad Sci USA 93: 2675-2679.
35. Søgaard-Andersen, L., Slack, F., Kimsey, H., and Kaiser, D. (1996) Intercellular C-signaling in Myxococcus xanthus involves a branched signal transduction pathway. Genes Dev 10: 740-754.
36. Spratt, B.G., Hedge, P.J., te Heesen, S., Edelman, A., and Broome-Smith, J.K. (1986) Kanamycin-resistant vectors that are analogues of plasmids pUC8, pUC9, pEMBL8 and pEMBL9. Gene 41: 337-342.
37. Stephens, K., and Kaiser, D. (1987) Genetics of gliding motility in Myxococcus xanthus: molecular cloning of the mgl locus. Mol Gen Genet 207: 256-266.
38. Thompson, J.D., Higgins, D.G., and Gibson, T.J. (1994) CLUSTAL w: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, positions-specific gap penalties and weight matrix choice. Nucleic Acids Res 22: 4673-4680.
39. Thöny-Meyer, L., and Kaiser, D. (1993) devRS, an auto regulated and essential genetic locus for fruiting body development in Myxococcus xanthus. J Bacteriol 175: 7450-7462.
40. Toal, D.R., Clifton, S.W., Roe, B.A., and Downard, J. (1995) The esg locus of Myxococcus xanthus encodes the E1α and E1β subunits of a branched-chain keto acid dehydrogenase. Mol Microbiol 16: 177-189.
41. Volz, K. (1993) Structural conservation in the CheY super-family. Biochemistry 32: 11741-11753.
42. Ward, M., and Zusman, D.R. (1997) Regulation of directed motility in Myxococcus xanthus. Mol Microbiol 24: 885-893.