Mechanisms of asthma exacerbation

Clinical and Experimental Allergy, Supplement

Volumn 28, Issue 5, 1998, Pages 181-186

  Johnston, S L ^a  

^a SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; BETA1 INTEGRIN; CYTOKINE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 4; MYELOPEROXIDASE; NITRIC OXIDE; RANTES; STEROID; VASCULAR CELL ADHESION MOLECULE 1;

ADENOVIRUS; ASTHMA; CONFERENCE PAPER; CORONAVIRUS; CYTOKINE PRODUCTION; DISEASE SEVERITY; HUMAN; IMMUNOPATHOGENESIS; INFLUENZA VIRUS; LOWER RESPIRATORY TRACT INFECTION; PARAINFLUENZA VIRUS; PRIORITY JOURNAL; RECURRENT DISEASE; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY TRACT INFLAMMATION; RHINOVIRUS; STEROID THERAPY; VIRUS INFECTION;

EID: 0031765334     PISSN: 09602178     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.1998.028s5181.x     Document Type: Conference Paper

References (34)

1. Johnston SL, Pattemore PK, Sanderson G et al. Community study of role of virus infections in exacerbations of asthma in 9-11 year old children. Br Med J 1995; 310:1225-8.
2. Nicholson KG, Kent J, Ireland DC. Respiratory viruses and exacerbations of asthma in adults. Br Med J 1993; 307:982-6.
3. Johnston SL, Pattemore PK, Sanderson G. et al. The relationship between upper respiratory infections and hospital admissions for asthma: a time trend analysis. Am J Respir Crit Care Med 1996; 154:654-60.
4. Chauhan AJ, Johnson A-WBR, Xie P, et al. Virus infections by RT-PCR in hospital admissions with acute respiratory illness. Arch Dis Child 1998 (submitted).
5. Campbell MJ, Holgate ST, Johnston SL. Trends in asthma mortality. Br Med J 1997; 315:1012.
6. Kaur B, Anderson HJ, Austin J et al. Prevalence of asthma symptoms, diagnosis, and treatment in 12-14 year old children across Great Britain (international study of asthma and allergies in childhood, ISAAC UK). Br Med J 1998; 316:118-24.
7. O'Hollaren MT, Yunginger JW, Offord KP, et al. Exposure to aeroallergen as a possible precipitating factor in respiratory arrest in young patients with asthma. N Engl J Med 1991; 324:359-63.
8. Chanarin N, Miles J, Beasley R, Holgate ST, Johnston SL. Seasonal distribution of episodes of acute severe asthma in adults. Thorax 1998; 52:A7.
9. Doull IJM, Lampe FC, Smith S, Schreiber Freezer NJ, Holgate ST. Effect of inhaled corticosteroids on episodes of wheezing associated with viral infection in school age children: randomised double blind placebo controlled trial. Br Med J 1997; 315:858-62.
10. Johnston SL. Problems and prospects of developing effective therapy for common cold viruses. Trends Microbiol 1997; 5:58-63.
11. Bates PJ, Sanderson G, Holgate ST, Johnston SL. A comparison of RT-PCR, in-situ hybridisation and in-situ RT-PCR for the detection of rhinovirus infection in paraffin sections. J Virol Meth 1997; 67:153-60.
12. Johnston SL, Papi A, Bates PJ, Mastronarde JG, Monick MM, Hunninghake GW. Low grade rhinovirus infection induces a prolonged release of IL-8 in pulmonary epithelium. J Immunol 1998; 160:6172-8.
13. Sanders SP, Siekierski ES, Porter JD, Richards SM, Proud D. Nitric oxide inhibits rhinovirus-induced cytokine production and viral replication in a human respiratory epithelial cell line. J Virol 1998; 72:934-42.
14. Gern JE, Galagan DM, Jarjour NN, Dick EC, Busse WW. Detection of rhinovirus 16 RNA in lower airway cells during experimentally induced infection. Am J Respir Crit Care Med 1997; 155:1159-61.
15. Bates PJ, Bardin PG, Fraenkel DJ, Sanderson G, Holgate ST, Johnston SL. Localisation of rhinovirus in the bronchial epithelium of experimentally infected human volunteers. Am J Respir Crit Care Med 1998; 157:A25.
16. Teran LM, Johnston SL, Schröder J, Church MK, Holgate ST. Role of nasal IL-8 in neutrophil recruitment and activation in children with virus-induced asthma. Am J Respir Crit Care Med 1997; 155:1362-6.
17. Grunberg K, Timmers MC, Smits HH et al. Effect of experimental rhinovirus 16 colds on airway hyperresponsiveness to histamine and interleukin-8 in nasal lavage in asthmatic subjects in-vivo. Clin Exp Allergy 1997; 27:36-45.
18. Calhoun WJ, Dick EC, Schwartz LB, Busse WW. A common cold virus, rhinovirus 16, potentiates airway inflammation after segmental antigen bronchoprovocation in allergic subjects. J Clin Invest 1994; 94:2200-8.
19. Seminario M-C, Squillace D, Bardin PG, Fraenkel DJ, Gleich GJ, Johnston SL. Increased levels of eosinophil major basic protein in nasal secretions in rhinovirus infections. J Allergy Clin Immunol 1995; 95:259.
20. Fraenkel DJ, Bardin PG, Sanderson G, Lampe F, Johnston SL, Holgate ST. Lower airways inflammation during rhinovirus colds in normal and asthmatic subjects. Am J Respir Crit Care Med 1995; 151:879-86.
21. Grunberg K, Smits HH, Timmers MC et al. Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects. Am J Respir Crit Care Med 1997; 156:609-16.
22. Coyle AJ, Erhard F, Bertrand C et al. Virus specific CD8 cells can switch to IL-5 production and induce airway eosinophilia. J Exp Med 1995; 181:1229-33.
23. + T cells control Th2-driven pathology during pulmonary respiratory syncytial virus infection. Eur J Immunol 1997; 27:3341-9.
24. Gern JE, Galagan DM, Jarjour NN, Kelly EAB, Busse WW. Cytokine and rhinovirus 16 (RV16) RNA in the lower airway of experimentally infected subjects. Am J Respir Crit Care Med 1996; 153:A17.
25. Papi A, Wilson S, Holgate ST, Johnston SL. Roles of ICAM-1, VCAM-1, NFκB and GATA in rhinovirus induced asthma. 1998 submitted.
26. Teran LM, Johnston SL, Holgate ST. Immunoreactive RANTES and MIP1α are increased in nasal aspirates of children with virus-induced asthma. Am J Respir Crit Care Med 1995; 151:A385.
27. Gern JE, Schroth MK, Konno S-I, Grimm EA, Busse WW. Rhinovirus and IFN-γ synergistically upregulate RANTES mRNA and secretion in bronchial epithelial cells. Am J Respir Crit Care Med 1997; 155:A684.
28. Coyle AJ, Tyers M, Church D et al. Upregulation of chemokine receptors on bronchial epithelial cells in vitro following rhinovirus 14 infection. Am J Respir Crit Care Med 1998; 157:A200.
29. Stellato C, Collins P, Ponath PD et al. Production of the novel C-C chemokine MCP-4 by airway cells and comparison of its biological activity to other C-C chemokines. J Clin Invest 1997; 99:926-36.
30. De Gouw HWFM, Grunberg K, Schot R, Kroes ACM, Dick EC, Sterk PJ. Relationship between exhaled nitric oxide and ainvay hyperresponsiveness following experimental rhinovirus infection in asthmatic subjects. Eur Respir J 1998; 11:126-32.
31. Folkerts G, Van der Linde HJ, Nijkamp FP. Virus-induced airway hyperresponsiveness in guinea pigs is related to a deficiency in nitric oxide. J Clin Invest 1995; 95:26-30.
32. Dumistrascu D, Sanderson G, Mukaida N, Matsushima K, Holgate ST, Johnston SL. IL-8 and AP-1 and κB-like sites are necessary for rhinovims induction of IL-8 promoter activity in A549 cell. J Allergy Clin Immunol 1997; 99:5403.
33. Mastronarde JG, Monick MM, Mukaida N, Matsushima K, Hunninghake GW. AP-1 is the primary transcription factor which cooperatively interacts with NFκB in RSV induced IL-8 gene expression in airway epithelium. Am J Respir Crit Care Med 1997; 155:A684.
34. Zhu ZW, Tang A, Ray Y, Wu O, Einarsson ML, Landry J, Gwaltney Jr, Elias JA. Rhinovirus stimulation of interleukin-6 in vivo and in vitro-Evidence for nuclear factor kB-dependent transcriptional activation. J Clin Invest 1996; 97:421.