Proper design of clinical trials for the assessment of bone graft substitutes

Clinical Orthopaedics and Related Research

Volumn 355, Issue SUPPL., 1998, Pages

  Cornell, Charles N ^a  

^a HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOENGINEERING; BIOMECHANICS; BONE GRAFT; BONE REMODELING; CLINICAL TRIAL; CONFERENCE PAPER; COST BENEFIT ANALYSIS; DATA ANALYSIS; DOSE CALCULATION; FOLLOW UP; FRACTURE HEALING; HUMAN; INTERMETHOD COMPARISON; PATIENT SELECTION; PRIORITY JOURNAL; PROSTHESIS MATERIAL; RANDOMIZATION;

EID: 0031764844     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1097/00003086-199810001-00034     Document Type: Conference Paper

References (18)

1. Anington ED, Smith WJ, Chambers HG, et al: Complications of iliac crest bone graft harvesting. Clin Orthop 329:300-309, 1996.
2. Brigthon CT, Shaman P, Heppenstall RB: Tibial nonunion treated with direct current capacitance coupling or bone graft. Clin Orthop 321:223-234, 1995.
3. Chapman MW, Bucholz R, Cornell CN: Treatment of acute fractures with a collagen calcium phosphate graft material. A randomized clinical trial. J Bone Joint Surg 79A:495-502; 1997.
4. Chapman MW, Gordon JE, Zissimos AG: Compression plate fixation of acute fractures of the diaphyses of the radius and ulna. J Bone Joint Surg 71A: 159-169, 1989.
5. Committee on Outcome Studies of the Academy of Orthopaedic Surgeons: Disabilities of the Arm, Shoulder, and Hand Instrument: Version 1.3. Rosemont, IL, American Academy of Orthopaedic Surgeons 1996.
6. Cornell CN: Current Assessment of Fracture Healing. In Brighton CT, Friedlaender GE, Lane JM (eds). Bone Formation and Repair. Rosemont, IL, American Academy of Orthopaedic Surgeons 499-504, 1994.
7. Gross M: Innovations in surgery: A proposal for Phase 1 clinical trials in surgery. J Bone Joint Surg 758:351-354, 1993.
8. Grundel RE, Chapman MW, Yee T, Moore DC: Autogenic bone marrow and porous hiphasic calcium phosphate ceramic tor segmental hone detects in the canine ulna. Clin Orthop 266:244-258, 1991.
9. Hu R, Hearn T, Yang J: Bone graft harvest site as a determinant of iliac bone strength. Clin Orthop 310:252-256, 1995.
10. Mize RD, Bueholz RW, Grogan DP: Surgical treatment of displaced, comminuted fractures of the distal end of the femur. J Bone Joint Surg 64A: 871-879, 1982.
11. Ostrum RF, Geel C: Indirect reduction and internal fixation of supracondylar femur fractures without bone graft. J Orthop Trauma 9:278-284, 1995.
12. Podsialdo D, Richardson S: The timed "get up and go": A test of basic functional mobility for elderly persons. J Am Geriatr Soc 39:142-148, 1991.
13. Simpson JM, Ebraheim NA, Jackson WT: Posterolateral bone graft of the tibia. Clin Orthop 251:200-206, 1990.
14. Varga E, Hu R, Hearn TC, et al: Biomechonical analysis of hemipelvic deformation after bone graft harvest from the posterior iliac crest. Spine 13: 1494-1499, 1996.
15. Watson JT, Anders M, Moed BR: Management strategies for bone loss in tibial shaft fractures. Clin Orthop 315:138-151, 1995.
16. Werntz J, Lane JM, Piez C, et al: The repair of segmental bone defects with collagen and marrow. Trans Orthop Res Soc 11:108, 1986.
17. Wright RR, Schmeling GJ, Schwab JP: The necessity of acute bone grafting in diaphyseal forearm fractures: A retrospective review. J Orthop Trauma 11:288-294, 1997.
18. Younger EM, Chapman MW: Morbidity at bone graft donor sites. J Orthop Trauma 3:192-199, 1989.