A comparative SAR study of thrombin receptor derived non peptide mimetics: Importance of phenyl/guanidino proximity for activity

Amino Acids

Volumn 15, Issue 3, 1998, Pages 211-220

  Alexopoulos, K ^a   Matsoukas, J ^a   Tselios, T ^a   Roumelioti, P ^a   Mavromoustakos, T ^b   Holada, K ^c  

^a UNIVERSITY OF PATRAS   (Greece)

^b INSTITUTE OF BIOLOGY   (Greece)

^c INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION   (Czech Republic)

Author keywords

Amino acids; Peptide mimetics; Platelet aggregation; Tethered ligand; Thrombin; TRAPs

Indexed keywords

1 (6 GUANIDOHEXANOYL) 4 (PHENYLACETYLAMIDOMETHYL)PIPERIDINE; 1 PHENYLACETYL 4 (6 GUANIDOHEXANOYL)PIPERAZINE; GUANINE NUCLEOTIDE BINDING PROTEIN; THROMBIN RECEPTOR; THROMBIN RECEPTOR ACTIVATING PEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOLECULAR CLONING; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN DEGRADATION; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; THROMBOCYTE AGGREGATION;

EID: 0031764439     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01318860     Document Type: Article

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