Differential effect of a selective cyclooxygenase-2 inhibitor versus indomethacin on renal blood flow in conscious volume-depleted dogs

Journal of Cardiovascular Pharmacology

Volumn 32, Issue 5, 1998, Pages 686-694

  Black, Shawn C ^a   Brideau, Christine ^a   Cirino, Maria ^a   Belley, Michel ^a   Bosquet, Joel ^a   Chan, Chi Chung ^a   Rodger, Ian W ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

Cyclooxygenase inhibition; Kidney; Nonsteroidal antiinflammatory drugs; Renal blood flow; Thromboxane B2

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 3 (3,4 DIFLUOROPHENYL) 4 [4 (METHYLSULFONYL)PHENYL] 2 (5H) FURANONE; 6 OXOPROSTAGLANDIN F1 ALPHA; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; INDOMETACIN; PROSTAGLANDIN E2; RENIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOG; DRUG BLOOD LEVEL; DRUG SELECTIVITY; ENZYME INHIBITION; HEART RATE; KIDNEY BLOOD FLOW; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; ORAL DRUG ADMINISTRATION; PLASMA RENIN ACTIVITY; POTASSIUM EXCRETION; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; SODIUM EXCRETION;

ANIMALS; BLOOD PRESSURE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; DOGS; FURANS; HEART RATE; INDOMETHACIN; ISOENZYMES; MALE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RENAL CIRCULATION; RENIN;

EID: 0031764281     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199811000-00002     Document Type: Article

References (21)

1. Lote CJ, Haylor J. Eicosanoids in renal function. Prostaglandins Leukot Essent Fatty Acids 1989;36:203-7.
2. Sugimoto Y, Namba T, Shigemoto R, Hegishi M, Ichikawa A, Narumiva S. Distinct cellular localization of mRNAs for the three subtypes of the prostaglandin E receptor in kidney. Am J Physiol 1994;266:F823-8.
3. Goppelt-Struebe M. Regulation of prostaglandin endoperoxide synthase (cyclooxygenase) isoenzyme expression. Prostaglandins Leukot Essent Fatty Acids 1995;52:213-22.
4. Smith WI, DeWitt DL. Biochemistry of prostaglandin endoperoxide H synthase-1 and synthase-2 and their differential susceptibility to nonsteroidal anti-inflammatory drugs. Semin Nephrol 1995;15:179-94.
5. Harris RC, McKanna JA, Akai Y, Jacobson HR, Dubois RN, Breyer MD. Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. J Clin Invest 1994;94:2504-10.
6. Kohan DE, Padilla E, Kutchera WA, Michael JR, Hughes AK. Endothelin-1 (ET-1) induction of cyclooxygenase-2 (COX-2) expression in rat mesangial cells. J Am Soc Nephrol 1994;(suppl 3):583.
7. Rzymkiewicz DM, DuMaine J, Morrison AR. IL-1β regulates rat mesangial cyclooxygenase II gene expression by tyrosine phosphorylation. Kidney Int 1995;47:1354-63.
8. Blasingham MC, Nasjiletti A. Differential renal effects of cyclooxygenase inhibition in sodium-replete and sodium-deprived dog. Am J Physiol 1980;239:F360-5.
9. Brideau C, Kargman S, Liu S, et al. A human whole blood assay for clinical evaluation of biochemical efficacy of cyclooxygenase inhibitors. Inflamm Res 1996;45:68-74.
10. Lonigro AJ, Itskovitz HD, Crowshaw K, McGiff JC. Dependency of renal blood flow on prostaglandin synthesis in the dog. Circ Res 1973;32:712-7.
11. Terragno NA, Terragno DA, McGiff JC. Contribution of prostaglandins to the renal circulation in conscious, anesthetized, and laparotomized dogs. Circ Res 1977;40:590-5.
12. McKenzie JK, Ryan JW, Lee MR. Effect of laparotomy on plasma renin activity in the rabbit. Nature 1967;215:542-3.
13. Stash and Zimmerman. 1975.
14. Oliver JA, Sciacca RR, Pinto J, Cannon PJ. Participation of the prostaglandins in the control of renal blood flow during acute reduction of cardiac output in the dog. J Clin Invest 1981;67:229-37.
15. Kemp RA, Genard J, Fourmanoir P, Caron N, Laekman CG, Herman A. Renal hemodynamics and blood flow autoregulation during acute cyclooxygenase inhibition in male rats. Am J Physiol 1995;268:F468-79.
16. Zimmerman BG. Effect of meclofenamate on renal vascular resistance in early Goldblatt hypertension in conscious and anesthetized dogs. Prostaglandins 1978;15:1027-34.
17. 2 secretion and excretion in conscious dogs. Am J Physiol 1979;235:F552-8.
18. Seymour AA, Zehr JE. Influence of prostaglandin synthesis on renin control mechanisms in the dog. Circ Res 1979;45:13-25.
19. Blasingham MC, Nasjiletti A. Contribution of renal prostaglandins to the natriuretic action of bradykinin in the dog. Am J Physiol 1979;237:F182-7.
20. Kirschenbaum MA, Stein JH. The effect of inhibition of prostaglandin synthesis on urinary sodium excretion in the conscious dog. J Clin Invest 1976;57:517-21.
21. Satoh S, Zimmerman BG. Influence of the renin-angiotensin system on the effect of prostaglandin synthesis inhibitors in the renal vasculature. Circ Res 36-7(suppl I):I-89-95.