The lack of bimodality in the effects of endogenous and exogenous prostaglandins on fat cell lipolysis in rats

Prostaglandins and Other Lipid Mediators

Volumn 56, Issue 1, 1998, Pages 43-52

  Girouard, Hélène ^a   Savard, Roland ^a  

^a UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

Author keywords

Adenosine; Aspirin; Fat cell lipolysis; Indomethacin; Isoproterenol; Prostaglandins

Indexed keywords

ADENOSINE DEAMINASE; GLYCEROL; INDOMETACIN; ISOPRENALINE; PROSTACYCLIN; PROSTAGLANDIN; PROSTAGLANDIN E2;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BETA ADRENERGIC STIMULATION; DOSE RESPONSE; DRUG MECHANISM; FEMALE; INHIBITION KINETICS; LIPOLYSIS; NONHUMAN; PROSTAGLANDIN SYNTHESIS; RAT;

ADENOSINE; ADENOSINE DEAMINASE; ADIPOCYTES; ADRENERGIC BETA-AGONISTS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPOPROSTENOL; FEMALE; GLYCEROL; INDOMETHACIN; ISOPROTERENOL; LIPOLYSIS; RATS; RATS, WISTAR;

EID: 0031763364     PISSN: 00906980     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0090-6980(98)00035-5     Document Type: Article

References (32)

1. Shaw J., Ramwell P.W. Release of prostaglandin from rat epididymal fat pad on nervous and hormonal stimulation. J. Biol. Chem. 243:1968;1498.
2. Christ E.J., Nugteren D.H. The biosynthesis and possible function of prostaglandins in adipose tissue. Biochim. Biophys. Acta. 218:1970;296.
3. Dalton C., Hope H.R. Cyclic AMP regulation of prostaglandin biosynthesis in fat cells. Prostaglandins. 6:1974;227.
4. 2 and prostacyclin in rat and human adipocytes. Biochem. J. 247:1987;389.
5. Irvine R.F. How is the level of free arachidonic acid controlled in mammalian cells? Biochem. J. 204:1982;3.
6. Chiappe De Cingolani G.E., Van Den Bosch H., Deenen L.I.M. Phospholipase A and lysophospholipase activities in isolated fat cells Effect of cyclic 3′,5′-AMP . Biochim. Biophys. Acta. 260:1972;387.
7. Van Den Bosch H. Intracellular phospholipases A. Biochim. Biophys. Acta. 604:1980;191.
8. 2 on human fat cell adenylate cyclase. J. Clin. Invest. 64:1979;609.
9. Gaion R.M., Tremto M., Murari L., Dorigo P., Ferro C., Fassina G. Prostacyclin and lipolysis in rat fat cells. Biochem. Pharmacol. 33:1984;3793.
10. 2 receptor binding and action in human fat cells. J. Clin. Endocrinol. Metab. 59:1984;7.
11. Aktories K., Schultz G., Jakobs K.H. Inhibitory regulation of adenylate cyclase by prostaglandins. Adv. Prostaglandin Thromboxane Leukotrienes Res. 12:1983;283.
12. Strong P., Coleman R.A., Humphrey P.P.A. Prostanoïd-induced inhibition of lipolysis in rat isolated adipocytes Probable involvement of EP3 receptors . Prostaglandins. 43:1992;559.
13. 2. Biochem. Pharmacol. 36:1987;4017.
14. Illiano G., Cuatrecasas P. Endogenous prostaglandins modulate lipolytic processes in adipose tissue. Nature: New Biology. 234:1971;72.
15. Dalton C., Hope H.R. Inability of prostaglandin synthesis inhibitor to affect adipose tissue lipolysis. Prostaglandins. 4:1973;641.
16. Fain J.N., Psychoyos S., Czernik A.J., Frost S., Cash W.D. Indomethacin, lipolysis and cyclic AMP accumulation in white fat cells. Endocrinology. 93:1973;632.
17. Fredholm B.B. Local regulation of lipolysis in adipose tissue by fatty acids, prostaglandins and adenosine. Med. Biol. 56:1978;249.
18. Fain J.N., Malbon C.C. Regulation of adenylate cyclase by adenosine. Mol. Cell. Biochem. 25:1979;143.
19. Després J.P., Bouchard C., Bukowiecki L., Savard R., Lupien J. Morphology and metabolism of human fat cells A reliability study . Int. J. Obes. 7:1983;231.
20. Kather H., Schroder F., Simon B. Microdetermination of glycerol using bacterial NADH-linked luciferase. Clin. Chim. Acta. 120:1982;295.
21. Daly J.W. Adenosine receptors. Adv. Cyclic Nucleotide Protein Phosphorylation Res. 19:1985;29.
22. Stiles G.L. Adenosine receptors Structure, function and regulation . Trends Pharmacol. Sci. 87:1986;486.
23. Vikmann H.L., Ranta S., Kiviluoto T., Ohisalo J.J. Different metabolic regulation by adenosine in omental and subcutaneous (s.c.) adipose tissue. Acta Physiol. Scand. 142:1991;405.
24. Kather H. Pathways of purine metabolism in human adipocytes. J. Biol. Chem. 265:1990;96.
25. Flower R.J., Vane J.R. Inhibition of prostaglandin biosynthesis. Biochemical Pharmacology. 23:1974;1439.
26. 2 receptors and homologous desensitization of isolated adipocytes. Endocrinology. 113:1983;1732.
27. Gaion R.M., Trento M., Murari L., Dorigo P., Ferro C., Fassina G. Prostacyclin and lipolysis in rat fat cells. Biochem. Pharmac. 33:1984;3793.
28. 2 and forskolin in modulation of cyclic AMP levels in rat epididymal adipocytes. Prostaglandins Leukotr. Med. 18:1988;151.
29. 2 can bimodally inhibit and stimulate the epididymal adipocyte adenylyl cyclase activity. Cellular Signalling. 4:1992;331.
30. Negishi M., Irie A., Sugimoto Y., Namba T., Ichikawa A. Selective coupling of prostaglandin E receptor EP3D to Gi and Gs through interaction of α-carboxylic acid of agonist and arginine residue of seventh transmembrane domain. J. Biol. Chem. 270:1995;16122.
31. Negishi M., Sugimoto Y., Ichikawa A. Molecular mechanisms of diverse actions of prostanoid receptors. Biochim. Biophys. Acta. 1259:1995;109.
32. α2-agonist UK 14304. Biochem. Pharmac. 49:1995;785.