메뉴 건너뛰기




Volumn 78, Issue 3, 1998, Pages 261-268

Effects of KRN4884 (a novel K+ channel opener), levcromakalim, nilvadipine and propranolol on endothelin-1-induced heart disorders in anesthetized rats

Author keywords

Electrocardiogram change; Endothelin; Heart disorder; K+ channel opener; KRN4884

Indexed keywords

5 AMINO N [2 (2 CHLOROPHENYL)ETHYL] N' CYANO 3 PYRIDINECARBOXAMIDINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM ANTAGONIST; ENDOTHELIN 1; LEMAKALIM; NILVADIPINE; POTASSIUM CHANNEL STIMULATING AGENT; PROPRANOLOL;

EID: 0031762801     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.78.261     Document Type: Article
Times cited : (1)

References (25)
  • 2
    • 0025014725 scopus 로고
    • The effect of diltiazem on the coronary haemodynamic and cardiac functional effects produced by intracoronary administration of endothelin-1 in the anaesthetized dog
    • Nichols AJ, Koster PF and Ohlstein EH: The effect of diltiazem on the coronary haemodynamic and cardiac functional effects produced by intracoronary administration of endothelin-1 in the anaesthetized dog. Br J Pharmacol 99, 597-601 (1990)
    • (1990) Br J Pharmacol , vol.99 , pp. 597-601
    • Nichols, A.J.1    Koster, P.F.2    Ohlstein, E.H.3
  • 3
    • 0025326435 scopus 로고
    • The arrhythmic action of endothelin in rats
    • Yorikane R and Koike H: The arrhythmic action of endothelin in rats. Jpn J Pharmacol 53, 259-263 (1990)
    • (1990) Jpn J Pharmacol , vol.53 , pp. 259-263
    • Yorikane, R.1    Koike, H.2
  • 4
    • 0027246420 scopus 로고
    • Effects of KRN2391, nicorandil and diltiazem on the changes in the electrocardiogram caused by endothelin-1 in anaesthetized rats
    • Harada K, Miwa A, Kaneta S, Izawa T, Fukushima H and Ogawa N: Effects of KRN2391, nicorandil and diltiazem on the changes in the electrocardiogram caused by endothelin-1 in anaesthetized rats. Br J Pharmacol 109, 679-684 (1993)
    • (1993) Br J Pharmacol , vol.109 , pp. 679-684
    • Harada, K.1    Miwa, A.2    Kaneta, S.3    Izawa, T.4    Fukushima, H.5    Ogawa, N.6
  • 8
    • 0028575842 scopus 로고
    • Cyanoamidines. II. Synthesis and pharmacological activity of N-arylalkyl-N′-cyano-3-pyridinecarboxamidines
    • Tokyo
    • Nakajima T, Nakajima S, Izawa T, Kashiwabara T and Munezuka Y: Cyanoamidines. II. Synthesis and pharmacological activity of N-arylalkyl-N′-cyano-3-pyridinecarboxamidines. Chem Pharm Bull (Tokyo) 42, 2483-2490 (1994)
    • (1994) Chem Pharm Bull , vol.42 , pp. 2483-2490
    • Nakajima, T.1    Nakajima, S.2    Izawa, T.3    Kashiwabara, T.4    Munezuka, Y.5
  • 9
    • 0029099969 scopus 로고
    • + channel opener, on the cardiovascular system in anaesthetized dogs: A comparison with levcromakalim, nilvadipine, and nifedipine
    • + channel opener, on the cardiovascular system in anaesthetized dogs: a comparison with levcromakalim, nilvadipine, and nifedipine. J Cardiovasc Pharmacol 26, 189-197 (1995)
    • (1995) J Cardiovasc Pharmacol , vol.26 , pp. 189-197
    • Izumi, H.1    Jinno, Y.2    Kaneta, S.3    Tanaka, Y.4    Okada, Y.5    Izawa, T.6    Ogawa, N.7
  • 11
    • 0014845425 scopus 로고
    • Antagonizing substances obtained from whale heart extract to vasopressin induced myocardial hypoxia
    • Hiramatsu Y, Izumi A, Tezuka T and Kurosawa Y: Antagonizing substances obtained from whale heart extract to vasopressin induced myocardial hypoxia. Jpn J Pharmacol 20, 313-324 (1970)
    • (1970) Jpn J Pharmacol , vol.20 , pp. 313-324
    • Hiramatsu, Y.1    Izumi, A.2    Tezuka, T.3    Kurosawa, Y.4
  • 12
    • 0019792516 scopus 로고
    • Effects of N-(2-hydroxyethyl)nicotinamidenitrate (SG-75) on methacholine-induced ECG changes in intact anesthetized rats
    • Aono J, Akiyama M and Sakai K: Effects of N-(2-hydroxyethyl)nicotinamidenitrate (SG-75) on methacholine-induced ECG changes in intact anesthetized rats. Jpn J Pharmacol 31, 823-830 (1981)
    • (1981) Jpn J Pharmacol , vol.31 , pp. 823-830
    • Aono, J.1    Akiyama, M.2    Sakai, K.3
  • 13
    • 0019473119 scopus 로고
    • Evaluation of drug effects in a new experimental model of angina pectoris in the intact anaesthetized rat
    • Sakai K, Akita M and Aono J: Evaluation of drug effects in a new experimental model of angina pectoris in the intact anaesthetized rat. J Pharmacol Methods 5, 325-336 (1981)
    • (1981) J Pharmacol Methods , vol.5 , pp. 325-336
    • Sakai, K.1    Akita, M.2    Aono, J.3
  • 16
    • 0026331961 scopus 로고
    • Electrophysiological effects of endothelin-1 on canine myocardial cells
    • Yorikane R, Koike H and Miyake S: Electrophysiological effects of endothelin-1 on canine myocardial cells. J Cardiovasc Pharmacol 17, Suppl 7, S159-S162 (1991)
    • (1991) J Cardiovasc Pharmacol , vol.17 , Issue.7 SUPPL.
    • Yorikane, R.1    Koike, H.2    Miyake, S.3
  • 17
    • 0024993896 scopus 로고
    • Effects of betaxolol on cardiohemodynamics and coronary circulation in anesthetized dogs: Comparison with atenolol and propranolol
    • Sato N, Suzuki J, Bessho H, Kitada Y, Narimatsu A and Tobe A: Effects of betaxolol on cardiohemodynamics and coronary circulation in anesthetized dogs: Comparison with atenolol and propranolol. Jpn J Pharmacol 54, 113-119 (1990)
    • (1990) Jpn J Pharmacol , vol.54 , pp. 113-119
    • Sato, N.1    Suzuki, J.2    Bessho, H.3    Kitada, Y.4    Narimatsu, A.5    Tobe, A.6
  • 18
    • 0018831213 scopus 로고
    • The effects of propranolol and acebutolol on left ventricular function and coronary haemodynamics in the conscious dog with myocardial ischaemia
    • Hillis WS, Hutton I and Lawrie TD: The effects of propranolol and acebutolol on left ventricular function and coronary haemodynamics in the conscious dog with myocardial ischaemia. Br J Pharmacol 68, 373-379 (1980)
    • (1980) Br J Pharmacol , vol.68 , pp. 373-379
    • Hillis, W.S.1    Hutton, I.2    Lawrie, T.D.3
  • 19
    • 26844555057 scopus 로고
    • Effect of endothelin on cytosolic calcium and membrane current in single ventricular myocytes
    • Lauer MR, Gunn MD and Ciusin W: Effect of endothelin on cytosolic calcium and membrane current in single ventricular myocytes. Circulation 80, Suppl II, II-194 (1989)
    • (1989) Circulation , vol.80 , Issue.2 SUPPL.
    • Lauer, M.R.1    Gunn, M.D.2    Ciusin, W.3
  • 20
    • 0026280596 scopus 로고
    • The arrhythmic and antifibrillatory effects of calcium antagonists
    • Billman GE: The arrhythmic and antifibrillatory effects of calcium antagonists. J Cardiovasc Pharmacol 18, Suppl 10, 8107-8117 (1991)
    • (1991) J Cardiovasc Pharmacol , vol.18 , Issue.10 SUPPL. , pp. 8107-8117
    • Billman, G.E.1
  • 22
    • 0025067476 scopus 로고
    • + channels in cardiac myocytes in an ATP- and temparature-dependent manner
    • + channels in cardiac myocytes in an ATP- and temparature-dependent manner. J Cardiovasc Pharmacol 15, 510-514 (1990)
    • (1990) J Cardiovasc Pharmacol , vol.15 , pp. 510-514
    • Martin, C.L.1    Chinn, K.2
  • 23
    • 0030983706 scopus 로고    scopus 로고
    • + channels openers in guinea pig ventricular cells
    • + channels openers in guinea pig ventricular cells. Br J Pharmacol 120, 1568-1574 (1997)
    • (1997) Br J Pharmacol , vol.120 , pp. 1568-1574
    • Shinbo, A.1    Iijima, T.2
  • 25
    • 9044246680 scopus 로고    scopus 로고
    • + currents by protein kinase C and adenosine. Implications for ischemic preconditioning
    • + currents by protein kinase C and adenosine. Implications for ischemic preconditioning. Circ Res 78, 443-454 (1996)
    • (1996) Circ Res , vol.78 , pp. 443-454
    • Liu, Y.1    Gao, W.D.2    Orourke, B.3    Marban, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.