Is functional dyspepsia largely explained by gastro-oesophageal reflux disease?

Bailliere's Clinical Gastroenterology

Volumn 12, Issue 3, 1998, Pages 463-476

  Wayman, John ^b   Griffin, S M ^b   Campbell, Frederick C ^a,b  

^a Dept of Gastroenterological Surgery ^*

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Functional dyspepsia; Gastro oesophageal reflux disease; pH monitoring; Reflux symptoms

Indexed keywords

ANTACID AGENT; CISAPRIDE; HISTAMINE H2 RECEPTOR ANTAGONIST; PROKINETIC AGENT; PROTON PUMP INHIBITOR; RANITIDINE;

ABDOMINAL PAIN; AMBULATORY MONITORING; ARTICLE; CLINICAL TRIAL; DIAGNOSTIC TEST; DIGESTIVE TRACT ENDOSCOPY; DYSPEPSIA; GALLSTONE; GASTROESOPHAGEAL REFLUX; HEARTBURN; HUMAN; PATHOPHYSIOLOGY; PEPTIC ULCER; PREVALENCE; PRIORITY JOURNAL; REFLUX ESOPHAGITIS; STOMACH PH; SYMPTOM;

EID: 0031762418     PISSN: 09503528     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0950-3528(98)90018-5     Document Type: Article

References (32)

1. Bates S & Sjoden P-O (1985) Registration of pain in a psychological perspective. Scandinavian Journal of Gastroenterology 20 (supplement 109): 15-18.
2. Colin-Jones DG (1988) Management of dyspepsia: report of a working party. Lancet i: 576-579.
3. Dent J (1997) Patterns of lower esophageal sphincter function associated with gastroesophageal reflux. American Journal of Medicine 103 (supplement 5A): S29-S32.
4. Earlam RJ (1970) Production of epigastric pain in duodenal ulcer by lower oesophageal acid perfusion. British Medical Journal 4: 714-716.
5. Farup PG, Wetterhus S, Osnes M & Ulshagen K (1997) Ranitidine effectively relieves symptoms in a subset of patients with functional dyspepsia. Scandinavian Journal of Gastroenterology 32: 755-759.
6. Galen (1916) On the Natural Faculties, vol. 3 (transl. Arthur John Brock). Loeb Classical Library Series.
7. Grainger SL, Klass HJ, Rake MO & Williams JG (1994) Prevalence of dyspepsia - the epidemiology of overlapping symptoms. Postgraduate Medical Journal 70: 154-161.
8. Halter F, Staub P, Hammer B et al (1997) Study with two prokinetics in functional dyspepsia and GORD: domperidone vs. cisapride. Journal of Physiology and Pharmacology 48: 185-192.
9. Howard PJ, Pryde A & Heading RC (1990) Relationship between gastro-oesophageal reflux and symptoms in patients referred for ambulatory pH monitoring. Journal of Gastrointestinal Motility 4: 231-239.
10. Howard PJ, Maher L, Pryde A & Heading RC (1989) Acid perfusion is a good screening-test for symptomatic oesophageal reflux. Gut 30(10): A1445.
11. Jebbink HJA, Van Bergehenegouwen GP & Smout AJPM (1993) Pathophysiology and treatment of functional dyspepsia. Scandinavian Journal of Gastroenterology 28: S200-S210: 8-14.
12. Johnson LF & DeMeester TR (1986) Development of the 24-hour intra-oesophageal pH monitoring composite scoring system. Journal of Clinical Gastroenterology (supplement 1): 52-58.
13. Lydeard S & Jones R (1989) Factors affecting the decision to consult with dyspepsia: comparison of consultera and non-consulters. Journal of the Royal College of General Practitioners 39: 495-498.
14. McDougall NI, Johnston BT, Collins JSA et al (1997) Disease progression in gastro-oesophageal reflux disease as determined by repeat oesophageal pH monitoring and endoscopy 3 to 4.5 years after diagnosis. European Journal of Gastroenterology and Hepatology 9: 1161-1167.
15. Nebel OT, Fornes MF & Castell DO (1976) Symptomatic gastro-oesophageal reflux: incidence and precipitating factors. American Journal of Digestive Diseases 21: 953-956.
16. Nyrén O, Adami HO, Bates et al (1986) Absence of therapeutic benefit from antacids or cimetidine in non-ulcer dyspepsia. New England Journal of Medicine 314: 339-343.
17. Richter JE, Hewson EG, Sinclair JW & Dalton CB (1991) Acid perfusion test and 24-hour esophageal pH monitoring with symptom index - comparison of tests for esophageal acid sensitivity. Digestive Diseases and Sciences 36: 565-571.
18. Riddell RH (1996). The biopsy diagnosis of gastroesophageal reflux disease, carditis, and Barrettsesophagus, and sequelae of therapy. American Journal of Surgical Pathology 20 (supplement 1): S31-S50.
19. Rune SJ (1997) Heartburn and dyspepsia: the utility of symptom analysis. Alimentary Pharmacology and Therapeutics 11 (supplement 2): 9-12.
20. Shi G, Bruley des Varannes S, Scarpignato et al (1995) Reflux symptoms in patients with normal oesophageal exposure to acid. Gut 37: 457-464.
21. Small PK, Loudon MA, Waldron B et al (1995) Importance of reflux symptoms in functional dyspepsia. Gut 36: 189-192.
22. Song F & Maynard A (1994) Functional Dyspepsia: A Review of Scientific and Policy Issues. Discussion Paper no. 119. York: Centre for Health Economics, University of York.
23. Stanghellini V, Tosetti C, Paternico A et al (1996) Risk indicators of delayed gastric-emptying of solids in patients with functional dyspepsia. Gastroenterology 110: 1036-1042.
24. Talley NJ (1997) Dyspepsia and heartburn: a clinical challenge. Alimentary Pharmacology and Therapeutics 11 (supplement 2): 1-8.
25. Talley NJ, Zinsmeister AR, Schleck CD & Melton LJ (1992) Dyspepsia and dyspepsia subgroups - a population-based study. Gastroenterology 102: 1259-1268.
26. Talley NJ, Zinsmeister AR, Schleck CD & Melton LJ (1994) Smoking, alcohol, and analgesics in dyspepsia and among dyspepsia subgroups - lack of an association in a community. Gut 35(5): 619-624.
27. Vantrappen G, Janssens J & Ghillebert G (1987) The irritable oesophagus - a frequent cause of angina-like pain. Lancet i: 1232-1234.
28. Vitale GC, Sadek S, Tulley FM et al (1985) Computerized 24-hour esophageal pH monitoring - a new ambulatory technique using radiotelemetry technique. Journal of Laboratory and Clinical Medicine 105: 686-693.
29. Waldron B, Cullen PT, Kumar R et al (1991) Evidence for hypomotility in non-ulcer dyspesia: a prospective multifactorial study. Gut 32: 246-251.
30. Watson RGP, Tham TCK, Johnston BT & McDougall NI (1997) Double blind cross-over placebo controlled study of omeprazole in the treatment of patients with reflux symptoms and physiological levels of acid reflux - the 'sensitive oesophagus'. Gut 40: 587-590.
31. Weusten B, Roelofs JMM, Akkermans LMA et al (1996) Objective determination of pH thresholds in the analysis of 24 h ambulatory esophageal pH monitoring. European Journal of Clinical Investigation 26: 151-158.
32. Wiener GJ, Morgan TM, Copper JB et al (1988) Ambulatory 24-hour oesophageal pH monitoring, reproducibility and variability of pH parameters. Digestive Diseases and Sciences 33(9): 1127-1133