Characterization of three related glucose repressors and genes they regulate in Saccharomyces cerevisiae

Genetics

Volumn 150, Issue 4, 1998, Pages 1377-1391

  Lutfiyya, Linda L ^a   Iyer, Vishwanath R ^b   DeRisi, Joe ^b   DeVit, Michael J ^a   Brown, Patrick O ^b   Johnston, Mark ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; REPRESSOR PROTEIN; ZINC FINGER PROTEIN;

ARTICLE; BINDING AFFINITY; CELLULAR DISTRIBUTION; DNA BINDING; GENE DISRUPTION; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENE REPRESSION; GLUCOSE UTILIZATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; BETA-FRUCTOFURANOSIDASE; BINDING SITES; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; GLUCOSE; GLYCOSIDE HYDROLASES; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION, GENETIC; ZINC FINGERS;

FUNGI; MYXOGASTRIA; SACCHAROMYCES CEREVISIAE;

EID: 0031761689     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. BAUDIN, A., O. OZIER-KALOGEROPOULOS, A. DENOUEL, F. LACROUTE and C. CULLIN, 1993 A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae. Nucleic Acids Res. 21: 3329.
2. BOHM, S., D. FRISHMAN and H. W. MEWES, 1997 Variations of the C2H2 zinc finger motif in the yeast genome and classification of yeast zinc finger proteins. Nucleic Acids Res. 25: 2464-2469.
3. BU, Y., and M. C. SCHMIDT, 1998 Identification of cis-acting elements in the suc2 promoter of Saccharomyces cerevisiae required for activation of transcription. Nucleic Acids Res. 26: 1002-1009.
4. CELENZA, J. L., and M. CARLSON, 1984 Cloning and genetic mapping of SNF1, a gene required for expression of glucose-repressible genes in Saccharomyces cerevisiae. Mol. Cell. Biol. 4: 49-53.
5. CELENZA, J. L., and M. CARLSON, 1986 A yeast gene that is essential for release from glucose repression encodes a protein kinase. Science 233: 1175-1180.
6. DERISI, J. L., V. R. IYER and P. O. BROWN, 1997 Exploring the metabolic and genetic control of gene expression on a genomic scale. Science 278: 680-686.
7. DEVIT, M. J., J. A. WADDLE and M. JOHNSTON, 1997 Regulated nuclear translocation of the Mig1 glucose repressor. Mol. Biol. Cell 8: 1603-1618.
8. ELDER, R. T., E. Y. LOH and R. W. DAVIS, 1983 RNA from the yeast transposable element Ty1 has both ends in the direct repeats, a structure similar to retrovirus RNA. Proc. Natl. Acad. Sci. USA 80: 2432-2436.
9. G-mediated glucose repression of the GAL1 promoter of Saccharomyces cerevisiae. Genetics 130: 295-304.
10. GEHRING, W. J., Y. Q. QIAN, M. BILLETER, K. FURUKUBU-TOKUNAGA, A. F. SCHIER et al., 1994 Homeodomain-DNA recognition. Cell 78: 211-223.
11. GOLDSTEIN, A., and J. O. LAMPEN, 1975 Beta-D-fructofuranoside fructohydrolase from yeast. Methods Enzymol. 42: 504-511.
12. GRIGGS, D. W., and M. JOHNSTON, 1991 Regulated expression of the GAL4 activator gene in yeast provides a sensitive genetic switch for glucose repression. Proc. Natl. Acad. Sci. USA 88: 8597-8601.
13. GUARENTE, L., and E. HOAR, 1984 Upstream activation sites of the CYC1 gene of Saccharomyces cerevisiae are active when inverted but not when placed downstream of the "TATA box." Proc. Natl. Acad. Sci. USA 81: 7860-7864.
14. HANES, S. D., and R. BRENT, 1989 DNA specificity of the bicoid activator protein is determined by homeodomain recognition helix residue 9. Cell 57: 1275-1283.
15. HEDGES, D., M. PROFT and K. D. ENTIAN, 1995 CAT8, a new zinc cluster-encoding gene necessary for derepression of gluconeogenic enzymes in the yeast Saccharomyces cerevisiae. Mol. Cell. Biol. 15: 1915-1922.
16. HORWITZ, M. S., and L. A. LOEB, 1986 Promoters selected from random DNA sequences. Proc. Natl. Acad. Sci. USA 83: 7405-7409.
17. HU, Z., J. O. NEHLIN, H. RONNE and C. A. MICHELS, 1995 MIG1-dependent and MIG1-independent glucose regulation of MAL gene expression in Saccharomyces cerevisiae. Curr. Genet. 28: 258-266.
18. JOHNSTON, M., and M. CARLSON, 1992 Regulation of carbon and phosphate utilization, pp. 193-281 in The Molecular and Cellular Biology of the Yeast Saccharomyces: Gene Expression, edited by J. R. BROACH, J. R. PRINGLE and E. W. JONES. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
19. KELEHER, C. A., M. J. REDD, J. SCHULTZ, M. CARLSON and A. D. JOHNSON, 1992 Ssn6-Tup1 is a general repressor of transcription in yeast. Cell 68: 709-719.
20. KLEIN, C. J., L. OLSSON, B. RONNOW, J. D. MIKKELSEN and J. NIELSEN, 1996 Alleviation of glucose repression of maltose metabolism by MIG1 disruption in Saccharomyces cerevisiae. Appl. Environ. Microbiol. 62: 4441-4449.
21. KLEIN, C., L. OLSSON and J. NIELSEN, 1998 Glucose control in Saccharomyces cerevisiae - the role of MIG1 in metabolic functions. Microbiology 144: 13-24.
22. LUNDIN, M., J. O. NEHLIN and H. RONNE, 1994 Importance of a flanking AT-rich region in target site recognition by the GC box-binding zinc finger protein MIG1. Mol. Cell. Biol. 14: 1979-1985.
23. LUTFIYYA, L. L., and M. JOHNSTON, 1996 Two zinc-finger-containing repressors are responsible for glucose repression of SUC2 expression. Mol. Cell. Biol. 16: 4790-4797.
24. MERCADO, J. J., O. VINCENT and J. M. GANCEDO, 1991 Regions in the promoter of the yeast FBP1 gene implicated in catabolite repression may bind the product of the regulatory gene MIG1. FEBS Lett. 291: 97-100.
25. MYERS, A. M., A. TZAGOLOFF, D. M. KINNEY and C. J. LUSTY, 1986 Yeast shuttle and integrative vectors with multiple cloning sites suitable for construction of lacZ fusions. Gene 45: 299-310.
26. NARDELLI, J., T. GIBSON and P. CHARNAY, 1992 Zinc finger-DNA recognition: analysis of base specificity by site-directed mutagenesis. Nucleic Acids Res. 20: 4137-4144.
27. NEHLIN, J. O., and H. RONNE, 1990 Yeast MIG1 repressor is related to the mammalian early growth response and Wilms' tumour finger proteins. EMBO J. 9: 2891-2898.
28. NEHLIN, J. O., M. CARLBERG and H. RONNE, 1991 Control of yeast GAL genes by MIG1 repressor: a transcriptional cascade in the glucose response. EMBO J. 10: 3373-3377.
29. NIEDENTHAL, R. K., L. RILES, M. JOHNSTON and J. H. HEGEMANN, 1996 Green fluorescent protein as a marker for gene expression and subcellular localization in budding yeast. Yeast 12: 773-786.
30. OLIPHANT, A. R., and K. STRUHL, 1987 The use of random-sequence oligonucleotides for determining consensus sequences. Methods Enzymol. 155: 568-582.
31. OZCAN, S., and M. JOHNSTON, 1995 Three different regulatory mechanisms enable yeast hexose transporter (HXT) genes to be induced by different levels of glucose. Mol. Cell. Biol. 15: 1564-1572.
32. OZCAN, S., and M. JOHNSTON, 1996 Two different repressors collaborate to restrict expression of the yeast glucose transporter genes HXT2 and HXT4 to low levels of glucose. Mol. Cell. Biol. 16: 5536-5545.
33. PAVLETICH, N. P., and C. O. PABO, 1991 Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A. Science 252: 809-817.
34. RONNE, H., 1995 Glucose repression in fungi. Trends Genet. 11: 12-17.
35. ROSE, M. D., F. WINSTON and P. HIETER. 1990 Methods in Yeast Genetics: A Laboratory Course Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
36. SAMBROOK, J., E. F. FRITSCH and T. MANIATHS, 1989 Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
37. SAROKIN, L., and M. CARLSON, 1984 Upstream region required for regulated expression of the glucose-repressible SUC2 gene of Saccharomyces cerevisiae. Mol. Cell. Biol. 4: 2750-2757.
38. SCHIESTL, R. H., and R. D. GIETZ, 1989 High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr. Genet. 16: 339-346.
39. SCHIESTL, R. H., P. MANIVASAKAM, R. A. WOODS and R. D. GIETZ, 1993 Introducing DNA into yeast by transformation. Methods 5: 79-85.
40. SCHULLER H. J., and K. D. ENTIAN. 1987 Isolation and expression analysis of two yeast regulatory genes involved in the derepression of glucose-repressible enzymes. Mol. Gen. Genet. 209: 366-373.
41. SHORE, P., A. J. WHITMARSH, R. BHASKARAN, R. J. DAVIS, J. P. WALTHO et al., 1996 Determinants of DNA-binding specificity of ETS-domain transcription factors. Mol. Cell. Biol. 16: 3338-3349.
42. SWIRNOFF, A. H., and J. MILBRANDT, 1995 DNA-binding specificity of NGFI-A and related zinc ringer transcription factors. Mol. Cell. Biol. 15: 2275-2287.
43. TREISMAN, J., P. GONCZY, M. VASHISHTHA, E. HARRIS and C. DESPLAN, 1989 A single amino acid can determine the DNA binding specificity of homeodomain proteins. Cell 59: 553-562.
44. TREITEL, M. A., and M. CARLSON, 1995 Repression by SSN6-TUP1 is directed by MIG1, a repressor/activator protein. Proc. Natl. Acad. Sci. USA 92: 3132-3136.
45. TRUMBLY, R. J., 1992 Glucose repression in the yeast Saccharomyces cerevisiae. Mol. Microbiol. 6: 15-21.
46. VALLIER, L. G., and M. CARLSON, 1994 Synergistic release from glucose repression by mig1 and ssn mutations in Saccharomyces cerevisiae. Genetics 137: 49-54.
47. WANG, J., and R. NEEDLEMAN, 1996 Removal of Mig1p binding site converts a MAL63 constitutive mutant derived by interchromosomal gene conversion to glucose insensitivity. Genetics 142: 51-63.
48. WEST, R., JR., R. R. YOCUM and M. PTASHNE, 1984 Saccharomyces cerevisiae GAL1-GAL10 divergent promoter region: location and function of the upstream activating sequence UASG. Mol. Cell. Biol. 4: 2467-2478.
49. WOLFE, K. H., and D. C. SHIELDS, 1997 Molecular evidence for an ancient duplication of the entire yeast genome. Nature 387: 708-713.
50. WRIGHT, W. E., and W. D. FUNK, 1993 CASTing for multicomponent DNA-binding complexes. Trends Biochem. Sci. 18: 77-80.
51. YOCUM, R. R., S. HANLEY, J. R. WEST and M. PTASHNE, 1984 Use of lacZ fusions to delimit regulatory elements of the inducible detergent GAL1-GAL10 promoters in Saccharomyces cerevisiae. Mol. Cell. Biol. 4: 1985-1998.