5-Hydroxytryptamine responses in immature rat rostral ventrolateral medulla neurons in vitro

Journal of Neurophysiology

Volumn 80, Issue 3, 1998, Pages 1033-1041

  Hwang, L L ^a   Dun, N J ^a,b  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b East Tennessee State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ALPHA METHYLSEROTONIN; BARIUM ION; CALCIUM ION; CHLORIDE ION; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (2 THIODIPHOSPHATE); KETANSERIN; MAGNESIUM ION; SEROTONIN; SEROTONIN 1 ANTAGONIST; SEROTONIN 1A AGONIST; SEROTONIN 1A ANTAGONIST; SEROTONIN 2 AGONIST; SEROTONIN 2 ANTAGONIST; SODIUM ION; SPIPERONE; TETRODOTOXIN; TETRYLAMMONIUM;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; BRAIN SLICE; BRAIN STEM; CONTROLLED STUDY; DEPOLARIZATION; HYPERPOLARIZATION; ION CONDUCTANCE; MEDULLA OBLONGATA; NEWBORN; NONHUMAN; PATCH CLAMP; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; RAT;

EID: 0031761033     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1998.80.3.1033     Document Type: Article

References (40)

1. B receptors to the same channels in hippocampus. Science 5: 1261-1265, 1986.
2. ANDRADE, R. AND NICOLL, R. A. Pharmacologically distinct actions of serotonin on single pyramidal neurones of the rat hippocampus recorded in vitro. J. Physiol. (Lond.) 394: 99-124, 1987.
3. 1A receptors mediated opposing responses on membrane excitability in rat association cortex. Neuroscience 40: 399-412, 1991.
4. h in central neurons. Neuron 2: 1535-1540, 1989.
5. BOBKER, D. H. AND WILLIAMS, J. T. The serotonergic inhibitory postsynaptic potential in propositus hypoglossi is mediated by two potassium currents. J. Neurosci. 15: 223-229, 1995.
6. BOESS, F. G. AND MARTIN, I. L. Molecular biology of 5-HT receptors. Neuropharmacology 33: 275-317, 1994.
7. COLINO, A. AND HALLIWELL, J. V. Differential modulation of three separate K conductances in hippocampal CA1 neurones by serotonin. Nature 328: 73-77, 1987.
8. DAMPNEY, R.A.L. The subretrofacial vasomotor nucleus: anatomical, chemical and pharmacological properties and role in cardiovascular regulation. Prog. Neurobiol. 42: 197-227, 1994.
9. DAVIES, M. F., DEISZ, R. A., PRINCE, D. A., AND PEROUTKA, S. J. Two distinct effects of 5-hydroxytryptamine on single cortical neurons. Brain Res. 423: 347-352, 1987.
10. GILLIS, R. A., HILL, K. J., KIRBY, J. S., QUEST, J. A., HAMOSH, P., NORMAL, W. P., AND KELLAR, K. J. Effect of activation of central nervous system serotonin 1A receptors on cardiorespiratory function. J. Pharmacol. Exp. Ther. 248: 851-857, 1989.
11. 3H-PAT. Nature 305: 140-142, 1983.
12. GUYENET, P. G. Role of the ventral medulla oblongata in blood pressure regulation. In: Central Regulation of Autonomic Functions, edited by A. D. Loewy and K. M. Spyer. New York: Oxford Univ. Press, p. 145-167, 1990.
13. 1A receptors. J. Pharmacol. Exp. Ther. 268: 1098-1106, 1994.
14. 1A receptor activation: ventral medullary site and mechanisms of action in the rat. J. Auton. Nerv. Syst. 42: 177-188, 1992.
15. LAUBIE, M., DROUILLAT, M., DABIRÉ, H., CHERQUI, C., AND SCHMITT, H. Ventrolateral medullary presser area: site of hypotensive and sympathoinhibitory effects of ±8-OH-DPAT on anaesthetised dogs. Eur. J. Pharmacol. 160: 385-394, 1989.
16. LEWIS, D. L. AND COOTE, J. H. The actions of 5-hydroxytryptamine on the membrane of putative sympatho-excitatory neurones in the rostral ventrolateral medulla of the adult rat in vitro. Brain Res. 609: 103-109, 1993.
17. 1A receptor antagonist. Pharmacol. Biochem. Behav. 38: 555-559, 1991.
18. LIN, H. H., Wu, S. Y., LAI, C. C., AND DUN, N. J. GABA- and glycine-mediated inhibitory postsynaptic potentials in neonatal rat rostral ventrolateral medulla neurons in vitro. Neuroscience 82: 429-442, 1998.
19. LOVICK, T. A. Cardiovascular responses to 5-HT in the ventrolateral medulla of the rat. J. Auton. Nerv. Syst. 28: 35-41, 1989a.
20. LOVICK, T. A. Systemic and regional haemodynamic responses to microinjection of 5-HT agonists in the rostral ventrolateral medulla in the rat. Neurosci. Lett. 107: 157-161, 1989b.
21. MANDAL, A. K., KELLAR, K. J., NORMAN, W. P., AND GILLIS, R. A. Stimulation of serotonin 2 receptors in the ventrolateral medulla of the cat results in nonuniform increase in sympathetic outflow. Circ. Res. 67: 1267-1280, 1990a.
22. MANDAL, A. K., ZHONG, P. Y., KELLAR, K. J., AND GILLIS, R. A. Ventrolateral medulla: an important site of action for the hypotensive effect of drugs that activate serotonin-1A receptors. J. Cardiovasc. Pharmacol. 15, Suppl. 7: S49-60, 1990b.
23. NOSJEAN, A. AND GUYENET, P. G. Role of ventrolateral medulla in sympatholytic effect of 8-OH-DPAT in rats. Am. J. Physiol. 260 (Regulatory Integrative Comp. Physiol. 29): R600-R609, 1991.
24. 1A receptor linked to inward-rectifying potassium current in hippocampal CA3 pyramidal cells. J. Neurophysiol. 71: 2161-2167, 1994.
25. PAPE, H. C. AND MCCORMICK, D. A. Noradrenaline and serotonin selectivity modulate thalamic burst firing by enhancing a hyperpolarization-activated cation current. Nature 340: 715-718, 1989.
26. PAZOS, A., CORTES, R., AND PALACIOS, J. M. Quantitative autoradiographic mapping of serotonin receptors in the rat brain. II. Serotonin-2 receptors. Brain Res. 346: 231-249, 1985.
27. PAZOS, A. AND PALACIOS, J. M. Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors. Brain Res. 346: 205-230, 1985.
28. + currents activated by 5-HT1A receptors on dorsal raphe neurones of the adult rat. J. Physiol. (Lond.) 469: 387-405, 1993.
29. 3H]spiroperidol. Mol. Pharmacol. 16: 687-699, 1979.
30. RICHARDSON, B. P., ENGEL, G., DONATSCH, P., AND STADLER, P. A. Identification of serotonin M-receptor subtypes and their specific blockade by a new class of drugs. Nature 316: 126-131, 1985.
31. STEINBUSCH, H.W.M. Distribution of serotonin immunoreactivity in the central nervous system of the rat cell bodies and terminals. Neuroscience 6: 557-618, 1981.
32. TAKAHASHI, T. AND BERGER, A. J. Direct excitation of rat spinal motoneurones by serotonin. J. Physiol. (Lond.) 423: 63-76, 1990.
33. 1A binding sites in the midline raphe and parapyramidal region of the ventral medulla oblongata of the rat. Neurosci. Lett. 108: 249-254, 1990.
34. UCHIMURA, N., CHERUBINI, E., AND NORTH, R. A. Inward rectification in rat nucleus accumbens neurons. J. Neurophysiol. 62: 1280-1286, 1989.
35. VAN NUETEN, J. M., JANSSEN, P. A., VAN BEEK, J., XHONNEUX, R., VERBEUREN, T. J., AND VANHOUTTE, P. M. Vascular effects of ketanserin (R41 468), a novel antagonist of 5-HT2 serotonergic receptors. J. Pharmacol. Exp. Ther. 218: 217-230, 1981.
36. VERTES, R. P. AND KOSCIS, B. Projections from the dorsal raphe nucleus to the brainstem: PHA-L analysis in the rat. J. Comp. Neurol. 340: 11 -26, 1994.
37. WANG, M. Y. AND DUN, N. J. 5-Hydroxytryptamine responses in neonate rat motoneurones in vitro. J. Physiol. (Lond.) 430: 87-103, 1990.
38. WANG, W. H. AND LOVICK, T. A. Inhibitory serotonergic effects on rostral ventrolateral medullary neurons. Pflügers Arch. 422: 93-97, 1992a.
39. WANG, W. H. AND LOVICK, T. A. Excitatory 5-HT2-mediated effects on rostral ventrolateral medullary neurones in rats. Neurosci. Lett. 141: 89-92, 1992b.
40. WILLIAMS, J. T., COLMER, W. F., AND PAN, Z. Z. Voltage- and ligand-activated inwardly rectifying currents in dorsal raphe neurons in vitro. J. Neurosci. 8: 3499-3506, 1988.