Weaning-induced development of δ-opioid receptors in rat brain: Differential effects of guanine nucleotides and sodium upon ligand-receptor recognition

British Journal of Pharmacology

Volumn 125, Issue 5, 1998, Pages 979-986

  Kelly, M D W ^a   Hill, R G ^b   Borsodi, A ^c   Toth, G ^c   Kitchen, I ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

^b NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

opioid receptors; Development; G proteins; Guanine nucleotides; Ontogeny; Receptor coupling; Weaning

Indexed keywords

DELTA OPIATE RECEPTOR; DELTORPHIN; GUANINE NUCLEOTIDE; NALOXONE; SODIUM ION;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ISOTOPE LABELING; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; WEANING;

ANIMALS; BRAIN; GUANYLYL IMIDODIPHOSPHATE; LIGANDS; NALTREXONE; OLIGOPEPTIDES; RATS; RATS, WISTAR; RECEPTORS, OPIOID, DELTA; SODIUM; WEANING;

EID: 0031760978     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702142     Document Type: Article

References (40)

1. BLUME, A.J. (1978). Opiate binding to membrane preparations of neuroblastoma x glioma hybrid cells NG108-15: effects of ions and nucleotides. Life Sci., 22, 1843-1852.
2. 5]enkephalin after pretreatment of brain membranes with guanine nucleotides. Proc. Natl. Acad. Sci. U.S.A., 80, 940-944.
3. CHANG, K.J., HAZUM, E., KILLIAN, A. & CUATRECASAS, P. (1981). Interactions of ligands with morphine and enkephalin receptors are differentially affected by guanine nucleotides. Mol. Pharmacol., 20, 1-7.
4. CHILDERS, S.R. (1991). Opioid receptor-coupled second messenger syetems. Life Sci., 48, 1991-2003.
5. CHILDERS, S.R., FLEMING, L.M., SELLEY, D.E., MCNUTT, R.W. & CHANG, K.-J. (1993). BW373U86: a nonpetidic δ-opioid agonist with novel receptor-G protein-mediated actions in rat brain membranes and neuroblastoma cells. Mol. Pharmacol., 44, 827-834.
6. CHILDERS, S.R. & SNYDER, S.H. (1980). Differential regulation by guanine nucleotides of opiate agonist and antagonist receptor interactions. J. Neurochem., 34, 583-593.
7. CLARK, J.A., LUI, L., PRICE, M., HERSH, B., EDELSON, M. & PASTERNAK, G.W. (1989). Kappa opiate receptor multiplicity: evidence for two U50,488-sensitive κ1 subtypes and a novel κ3 subtype. J. Pharmacol. Exp. Ther., 251, 461-468.
8. COSTA, T., LANG, J., GLESS, C. & HERZ, A. (1989). Spontaneous association between opioid receptors and GTP- binding regulatory proteins in native membranes: Specific regulation by antagonists and sodium ions. Mol. Pharmacol., 37, 383-394.
9. COX, B.M. (1993). Opioid receptor-G protein interactions:acute and chronic effects of opioids. In Opioids I. ed. Herz, A. pp. 147-188: Springer Verlag.
10. CROOK, T.J., KITCHEN, I. & HILL, R.G. (1992). Effects of the δ-opioid receptor antagonist naltrindole on antinociceptive responses to selective δ-agonists in post weanling rats. Br. J. Pharmacol., 107, 573-576.
11. CROOK, T.J., KITCHEN, I. & HILL, R.G. (1993). Differential antagonism of the antinociceptive effects of δ-opioid receptor agonists by the δ-antagonist naltriben in post weanling rats. Pharmacol. Commun., 3, 351-356.
12. 6]enkephalin and naltrindole 5′-isothiocyanate: Evidence for delta receptor subtypes. J. Pharmacol. Exp. Ther., 257, 1069-1075.
13. KIEFFER, B.L. (1995). Recent advances in molecular recognition and signal transduction of active peptides: Receptors for opioid peptides. Cell. Mol. Neurobiol., 15, 615-635.
14. KITCHEN, I., CROOK, T.J., MUHAMMAD, B.Y. & HILL, R.G. (1994). Evidence that weaning stimulates the developmental expression of a δ-opioid receptor subtype in the rat. Dev. Brain Res., 78, 147-150.
15. KITCHEN, I., LESLIE, F.M., KELLY, M., BARNES, R., CROOK, T.J., HILL, R.G., BORSODI, A., TOTH, G., MELCHIORRI, P. & NEGRI, L. (1995). Development of δ-opioid receptor subtypes and the regulatory role of weaning:radioligand binding, autoradiography and in situ hybridisation studies. J. Pharmacol. Exp. Ther., 275, 1597-1607.
16. KOSTERLITZ, H.W., PATERSON, S.J., ROBSON, L.E. & TRAYNOR, J.R. (1987). Effects of cations on binding, in membrane suspensions, of various opioids at μ-sites of rabbit cerebellum and κ-sites of guinea-pig cerebellum. Br. J. Pharmacol., 91, 431-437.
17. LOWRY, O.H., ROSEBROUGH, N.J., FARR, L. & RANDALL, R.J. (1951). Protein measurement with the Folin phenol reagent. J. Biol. Chem., 193, 265-275.
18. MATTIA, A., FARMER, S.C., TAKEMORI, A.E., SULTANA, M., PORTOGHESE, P.S., MOSBERG, H.I., BOWEN, W.D. & PORRECA, F. (1992). Spinal opioid delta antinociception in the mouse: Mediation by a 5′NTII-sensitive delta receptor subtype. J. Pharmacol. Exp. Ther., 260, 518-525.
19. MUHAMMAD, B.Y. & KITCHEN, I. (1993). Effect of delayed weaning on opioid receptor control of swim-stress-induced antinociception in the developing rat. Br. J. Pharmacol., 109, 651-654.
20. OTT, S., COSTA, T. & HERZ, A. (1988). Sodium modulates opioid receptors through a membrane component different from G proteins:demonstration by target size analysis. J. Biol. Chem., 263, 10524-10533.
21. PASTERNAK, G.A. & WOOD, P.J. (1986). Minireview: Multiple mu opiate receptors. Life Sci., 38, 1889-1898.
22. PERT, C.B. & SNYDER, S.H. (1974). Opiate receptor binding of agonists and antagonists affected differentially by sodium. Mol. Pharmacol., 10, 868-879.
23. PFEIFFER, A., SADEE, W. & HERZ, A. (1982). Differential regulation of the μ-, δ- and κ-opiate receptor subtypes by guanyl nucleotides and metal ions. Neurosci., 2, 912-917.
24. POLASTRON, J. & JAUZAC, P. (1994). Different subtypes of opioid receptors have different affinities for G-proteins. Cell. Mol. Neurobiol., 40, 389-401.
25. PRATHER, P.L., LOH, H.H. & LAW, P.-Y. (1994a). Interaction of δ-opioid receptors with multiple G-proteins: a non-relationship between agonist potency to inhibit adenylyl cyclase and to activate G-proteins. Mol. Pharmacol., 45, 997-1003.
26. PRATHER, P.L., MCGINN, T.M., ERICKSON, L.J., EVANS, C.J., LOH, H.H. & LAW, P.-Y. (1994b). Ability of δ-opioid receptors to interact with multiple G-proteins is independant of receptor density. J. Biol. Chem., 269, 21293-21302.
27. PUTTFARKEN, P., WERLING, L.L., BROWN, S.R., COTE, T.E. & COX, B.M. (1986). Sodium regulation of agonist binding at opioid receptors. 1. Effects of sodium replacement on binding at μ- and δ-type receptors in 7315C and NG108-15 cells and cell membranes. Mol. Pharmacol., 30, 81-89.
28. RICHARDSON, A., DEMOLIOU-MASON, C. & BARNARD, E.A. (1992). Guanine nucleotide-binding protein-coupled and -uncoupled states of opioid receptors and their relevance to the determination of subtypes. Proc. Natl. Acad. Sci. U.S.A., 89, 10198-10202.
29. + and Other Divalent Cations on the Binding of Tritiated Opioid Ligands. J. Neurochem., 59, 467-472.
30. SOFUOGLU, M., PORTOGHESE, P.S. & TAKEMORI, A.E. (1991). Differential antagonism of delta opioid agonists by naltrindole and its benzofuran anaiog (NTB) in mice: Evidence for delta opioid receptor subtypes. J. Pharmacol. Exp. Ther., 257, 676-680.
31. SPETEA, M., DARULA, Z., TOTH, G. & BORSODI, A. (1997). Synthesis and binding characteristics of the highly selective radiolabelled deltorphin analogues containing 2-aminotetralin-2-carboxylic acid in position 3. Neuropeptides, 31, 483-488.
32. SZUCS, M., J.W., S., OETTING, G.M., MOUDY, A.M. & COSCIA, C.J. (1987). Guanine nucleotide and cation regulation of μ, δ and κ-opioid receptor binding: evidence for differential postnatal development in rat brain. J. Neurochem., 48, 1165-1170.
33. TOTH, G., DARULA, Z., PETER, A., FULOP, F., TOURWE, D., JASPERS, H., VERHEYDEN, P., BOCSKEY, Z., TOTH, Z. & BORSODI, A. (1997). Conformationally Constrained Deltorphin Analogs with 2-Aminotetralin-2-Carboxylic Acid in Position 3. J. Med. Chem., 40, 990-995.
34. TRAYNOR, J. (1989). Subtypes of the κ-opioid receptor: fact or fiction? Trends Pharmacol. Sci., 10, 52-53.
35. UNTERWALD, E.M., KNAPP, C. & ZUKIN, R.S. (1991). Neuroanatomical localization of κ1 and κ2 opioid receptors in rat and guinea-pig brain. Brain Res., 562, 57-65.
36. WERLING, L.L., BROWN, S. & COX, B.M. (1984). The sensitivity of opioid receptor types to regulation by sodium and GTP. Neuropeptides, 5, 137-140.
37. WERLING, L.L., BROWN, S.R., PUTTFARCKEN, P. & COX, B.M. (1986). Sodium regulation of agonist binding at opioid receptors II. Effects of sodium replacement on opioid binding in guinea pig cortical membranes. Mol. Pharmacol., 30, 90-95.
38. WILD, K.D., FANG, L., MCNUTT, R.W., CHANG, K.-J., TOTH, G., YAMAMURA, H.I. & PORRECA, F. (1993). Binding of BW373U86, a non-peptide δ-opioid receptor agonist is not regulated by guanine nucleotides and sodium. Eur. J . Pharmacol., 246, 289-292.
39. WOLLEMAN, M., BENHYE, S. & SIMON, J. (1993). The kappa opioid receptor: evidence for the different subtypes. Life Sci., 52, 599-611.
40. ZAJAC, J.M. & ROQUES, B.P. (1985). Differences in binding properties of μ and δ opioid receptor subtypes from rat brain: Kinetic analysis and effects of ions and guanine nucleotides. Journal of Neurochemistry., 44, 1605-1614.