Multicenter comparative trial of ciprofloxacin versus cefuroxime axetil in the treatment of acute rhinosinusitis in a primary care setting

Clinical Therapeutics

Volumn 20, Issue 5, 1998, Pages 921-932

  Weis, Mark ^a,c   Hendrick, Kim ^a   Tillotson, Glenn ^b   Gravelle, Kathleen ^b  

^a Pharmaceutical Division ^*

^b BAYER CORPORATION   (United States)

^c Family Health Center   (United States)

Author keywords

Acute sinusitis; Cefuroxime axetil; Ciprofloxacin; Primary care

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; CEFPROZIL; CEFUROXIME AXETIL; CEPHALOSPORIN; CIPROFLOXACIN; CLARITHROMYCIN; CLAVULANIC ACID; COTRIMOXAZOLE; LEVOFLOXACIN; LORACARBEF; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN; TROVAFLOXACIN;

ANTIBIOTIC THERAPY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DRUG EFFICACY; DRUG SAFETY; DRUG SCREENING; FEMALE; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; PARANASAL SINUSITIS; PRIMARY MEDICAL CARE; RANDOMIZED CONTROLLED TRIAL; STATISTICAL ANALYSIS; TREATMENT OUTCOME; VAGINITIS;

EID: 0031760824     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/S0149-2918(98)80074-X     Document Type: Article

References (15)

1. Gwaltney JM. Acute community-acquired sinusitis. Clin Infect Dis. 1996;23: 1209-1225.
2. Lanza DC, Kennedy DW. Adult rhinosinusitis defined. Otolaryngol Head Neck Surg. 1997;117:51-57.
3. Orlandi RR, Kennedy DW. Surgical management of rhinosinusitis. Am J Med Sci. 1998;316:29-38.
4. Gwaltney JM Jr, Scheid WM, Sande MA, Sydnor A Jr. The microbial etiology and antimicrobial therapy of adults with acute community-acquired sinusitis: A fifteen-year experience at the University of Virginia and review of other selected studies. J Allergy Clin Immunol. 1992;90:457-462.
5. Doern GV, Brueggemann AB, Pierce G, et al. Antibiotic resistance among clinical isolates of Haemophilus influenzae in the United States in 1994 and 1995 and detection of beta-lactamase positive strains resistant to amoxicillin-clavulanate: Results of a national multicenter study. Antimicrob Agents Chemother. 1997;41: 292-297.
6. Doern GV, Brueggemann AB, Pierce G, et al. Prevalence of antimicrobial resistance among 723 outpatient clinical isolates of Moraxella catarrhalis in the United States in 1994 and 1995: Results of a 30-center national surveillance study. Antimicrob Agents Chemother. 1996;40:2884-2886.
7. Doern GV, Brueggemann AB, Holley HP Jr, Rauch AM. Antimicrobial resistance of Streptococcus pneumoniae recovered from outpatients in the United States during the winter months of 1994 to 1995: Results of a 30-center national surveillance study. Antimicrob Agents Chemother. 1996;40:1208-1213.
8. Thornsberry C, Ogilvie P, Kahn J, et al. Surveillance of antimicrobial resistance in Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United States in 1996-1997 respiratory season. Diagn Microbiol Infect Dis. 1997;29:249-257.
9. Klein GL, Whalen E, Echols RM, Heyd A. Ciprofloxacin versus cefuroxime axetil in the treatment of adult patients with acute bacterial sinusitis. J Otolaryngol. 1998;27:10-16.
10. Heyd A, Echols R, Shan M, et al. Oral ciprofloxacin vs cefuroxime axetil in the treatment of acute sinusitis. Presented at 35th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 17-20, 1995; San Francisco, California. Abstract LM-31.
11. Huck W, Shan M, Tosiello R, et al. Double-blind comparative trial of ciprofloxacin (CIP) vs clarithromycin (CLR) in the treatment of acute bacterial sinusitis. Presented at American College of Allergy Asthma and Immunology Meeting; November 8-9, 1997; San Diego, California. Abstract P57.
12. Kalliner MA, Osguthorpe DJ, Fireman P, et al. Sinusitis: Bench to bedside. J Allergy Clin Immunol. 1997;99(Suppl): S829-S848.
13. National Data Trends Inc. Antibiotic Prescriptions - USA. Plymouth, Pennsylvania: IMS; 1998.
14. McCraig LF, Hughes JM. Trends in antimicrobial drug prescribing among office-based physicians in the United States. JAMA. 1995;273:214-219.
15. Hickey ML, Thornsberry C, Diakun DR, et al. Activity of ciprofloxacin against S pneumoniae (Sp), H influenzae (Hi), and M catarrhalis (Mc): Has it changed in the last decade? 1998. Presented at 38th Interscience Conference on Antimicrobial Agents and Chemotherapy; September 24-27, 1998; San Diego, California. Abstract 16545, poster E020.