The role of azathioprine in the management of retinal vasculitis

Eye

Volumn 12, Issue 5, 1998, Pages 783-788

  Greenwood, A J ^a   Stanford, M R ^a   Graham, E M ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

Azathioprine; Immune suppression; Retinal vasculitis

Indexed keywords

AZATHIOPRINE; STEROID;

ADOLESCENT; ADULT; AGED; ARTICLE; BEHCET DISEASE; CHORIORETINOPATHY; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; EYE INFLAMMATION; FEMALE; HUMAN; IDIOPATHIC DISEASE; JUVENILE RHEUMATOID ARTHRITIS; MALE; RECURRENCE RISK; RETINA VASCULITIS; RETROSPECTIVE STUDY; SARCOIDOSIS; SIDE EFFECT; SYMPATHETIC OPHTHALMIA; VISUAL ACUITY; VOGT KOYANAGI SYNDROME;

EID: 0031759575     PISSN: 0950222X     EISSN: None     Source Type: Journal    
DOI: 10.1038/eye.1998.203     Document Type: Article

References (14)

1. Howe LJ, Stanford MR, Edelsten C, Graham EM. The efficacy of systemic corticosteroids in sight-threatening retinal vasculitis. Eye 1994;8:443-7.
2. Newell FW, Krill AE. Treatment of uveitis with azathioprine (Imuran). Trans Ophthalmol Soc UK 1967;87:499-511.
3. Lessof MH, Jeffrys DB, Lehner T, Sanders MD. Corticosteroids and azathioprine: their use in Behçet's syndrome. In: Lehner T, Barnes CG, editors. Behçet's syndrome: clinical and immunological features. London: Academic Press, 1979:218-26.
4. Andrasch RH, Pirofsky B, Burns RP. Immunosuppressive therapy for severe chronic uveitis. Arch Ophthalmol 1978;96:247-51.
5. Lightman S. Use of steroids and immunosuppressive drugs in the management of posterior uveitis. Eye 1991;5:294-8.
6. Vitale AT, Rodriguez A, Foster CS. Low dose cyclosporin A therapy in treating chronic, noninfectious uveitis. Ophthalmology 1996;103:365-73; discussion 373-4.
7. Graham EM, Sanders MD, James DG, Hamblin A, Kasp Grochowska E, Dumonde D. Cyclosporin in the treatment of posterior uveitis. Trans Ophthalmol Soc UK 1985;104:146-51.
8. Yazici H, Pazarli H, Barnes CG, Tuzun Y, Silman A, Serdaroglu S, et al. A controlled trial of azathioprine in Behçet's syndrome. N Engl J Med 1990;322:281-5.
9. Hamuryudan V, Ozyazgan Y, Hizli N, Mat C, Yurdakul S, Tuzun Y, et al. Azathioprine in Behçet's syndrome: effects of long-term prognosis. Arthritis Rheum 1997;40:769-74.
10. Hakin KN, Pearson RV, Lightman SL. Sympathetic ophthalmia: visual results with modern immunosuppressive therapy. Eye 1992;6:453-5.
11. Kotter I, Durk H, Saal J, Fierlbeck G, Pleyer U, Ziehut M. Therapy of Behçet's disease. Ger J Ophthalmol 1996;5:92-7.
12. Anstey A, Lennard L, Mayou SC, Kirby JD. Pancytopenia related to azathioprine: an enzyme deficiency caused by a common genetic polymorphism [review]. J R Soc Med 1992;85:752-6.
13. Weinshilboum RM, Sladek SL. Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity. Am J Hum Genet 1980;32:651-62.
14. Dumonde DC, Kasp-Grochowska E, Graham E, Sanders MD, Faure JP, de Kozak, van Tuyen V. Anti-retinal autoimmunity and circulating immune complexes in patients with retinal vasculitis. Lancet 1982;2:787-92