The influence of DNA ploidy of a human tumor cell line on the frequencies of micronuclei or chromosome aberrations after irradiation

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 418, Issue 1, 1998, Pages 49-57

  Takagi, Takehisa ^a   Sasai, Keisuke ^a   Shibamoto, Yuta ^b   Akagi, Kiyoshi ^c   Oya, Natsuo ^a   Shibata, Toru ^a   Kim, Jeman ^d   Hiraoka, Masahiro ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KANSAI MEDICAL UNIVERSITY   (Japan)

^d KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Fluorescence in situ hybridization; Micronucleus assay; Ploidy; Premature chromosome condensation; Radiosensitivity

Indexed keywords

CELL NUCLEUS DNA;

ARTICLE; CELL LINE; CELL SURVIVAL; CHROMOSOME 4; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA CONTENT; DNA STRAND BREAKAGE; FIBROSARCOMA; FISH; HUMAN; HUMAN CELL; MICRONUCLEUS; PLOIDY; PRIORITY JOURNAL; RADIATION; RADIOSENSITIVITY;

CELL SURVIVAL; CHROMOSOME ABERRATIONS; DNA, NEOPLASM; HELA CELLS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; MICRONUCLEUS TESTS; PLOIDIES; TUMOR CELLS, CULTURED;

EID: 0031759428     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(98)00115-6     Document Type: Article

References (33)

1. Brock W.A., Baker F.L., Wike J.L., Sivon S.L., Peters L.J. Cellular radiosensitivity of primary head and neck squamous cell carcinomas and local tumor control. Int. J. Radiat. Oncol. Biol. Phys. 18:1990;1283-1286.
2. Brown J.M., Evans J.W. Fluorescence in situ hybridization: an improved method of quantitating chromosome damage and repair. Br. J. Radiol. 24:1992;61-64. Suppl.
3. Deacon J., Peckham M.J., Steel G.G. The radioresponsiveness of human tumours and the initial slope of the cell survival curve. Radiother. Oncol. 2:1984;317-323.
4. Joensuu H. DNA flow cytometry in the prediction of survival and response to radiotherapy in head and neck cancer. A review. Acta Oncol. 29:1990;513-516.
5. Sasai K., Evans J.W., Kovacs M.S., Brown J.M. Prediction of human cell radiosensitivity: comparison of clonogenic assay with chromosome aberrations scored using premature chromosome condensation with fluorescence in situ hybridization. Int. J. Radiat. Oncol. Biol. Phys. 30:1994;1127-1132.
6. Schwartz J.L., Mustafi R., Beckett M.A., Weichselbaum R.R. Prediction of the radiation sensitivity of human squamous cell carcinoma cells using DNA filter elution. Radiat. Res. 123:1990;1-6.
7. Shibamoto Y., Streffer C., Fuhrmann C., Budach V. Tumor radiosensitivity prediction by cytokinesis-block micronucleus assay. Radiat. Res. 128:1991;293-300.
8. Wandl E.O., Ono K., Kain R., Herbsthofer T., Hienert G., Höbarth K. Linear correlation between surviving fraction and the micronucleus frequency. Int. J. Radiat. Biol. 56:1989;771-775.
9. Weichselbaum R.R., Beckett M.A., Vijayakumar S., Simon M.A., Awan A.M., Nachman J., Panje W.R., Goldman M.E., Tybor A.G., Moran W.J., Vokes E.E., Ahmed-Swan S., Farhangi E. Radiobiological characterization of head and neck and sarcoma cells derived from patients prior to radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 19:1990;313-319.
10. West C.M., Davidson S.E., Hunter R.D. Evaluation of surviving fraction at 2 Gy as a potential prognostic factor for the radiotherapy of carcinoma of the cervix. Int. J. Radiat. Biol. 56:1989;761-765.
11. E.J. Hall, DNA strand breaks and chromosomal aberrations, in: Radiobiology for the Radiologist, 4th edn., J.B. Lippincott, Philadelphia, 1994, pp. 15-27.
12. Wlodek D., Hittelman W.N. The relationship of DNA and chromosome damage to survival of synchronized X-irradiated L5178Y cells: I. Initial damage. Radiat. Res. 115:1988;550-565.
13. Bedford J.S. Sublethal damage, potentially lethal damage, and chromosomal aberrations in mammalian cells exposed to ionizing radiations. Int. J. Radiat. Oncol. Biol. Phys. 21:1991;1457-1469.
14. Joshi G.P., Nelson W.J., Revell S.H., Shaw C.A. X-ray-induced chromosome damage in live mammalian cells, and improved measurements of its effects on their colony-forming ability. Int. J. Radiat. Biol. 41:1982;161-181.
15. Pantelias G.E., Maillie H.D. The use of peripheral blood mononuclear cell prematurely condensed chromosomes for biological dosimetry. Radiat. Res. 99:1984;140-150.
16. Evans J.W., Chang J.A., Giaccia A.J., Pinkel D., Brown J.M. The use of fluorescence in situ hybridisation combined with premature chromosome condensation for the identification of chromosome damage. Br. J. Cancer. 63:1991;517-521.
17. Midander J., Revesz L. The micronucleus (MN) in irradiated cells as a measure of survival. Br. J. Cancer. 41(4):1980;204. Suppl.
18. Stap J., Aten J.A. Comparison of radiation sensitivity for three cell lines as measured by the cloning assay and the micro-nucleus test. Strahlenther. Onkol. 166:1990;761-763.
19. Countryman P.I., Heddle J.A. The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes. Mutat. Res. 41:1976;321-332.
20. Ramalho A., Sunjevaric I., Natarajan A.T. Use of the frequencies of micronuclei as quantitative indicators of X-ray-induced chromosomal aberrations in human peripheral blood lymphocytes: comparison of two methods. Mutat. Res. 207:1988;141-146.
21. Yu J.M., Zhang H., Wang S.Q., Miao H.Q., Yang L.H., Chen Y.T., Tian G.D. DNA ploidy analysis of effectiveness of radiation therapy for cervical carcinoma. Cancer. 68:1991;76-78.
22. Shibamoto Y., Nishimoto S., Shimokawa K., Hisanaga Y., Zhou L., Wang J., Sasai K., Takahashi M., Abe M., Kagiya T. Characteristics of fluorinated nitroazoles as hypoxic cell radiosensitizers. Int. J. Radiat. Oncol. Biol. Phy. 16:1989;1045-1048.
23. Murata R., Nishimura Y., Shibamoto Y., Hiraoka M., Abe M. Changes in cell proliferative parameters of SCC VII and EMT6 murine tumors after single-dose irradiation. Jpn. J. Cancer Res. 87:1996;662-668.
24. Shibata T., Shibamoto Y., Oya N., Sasai K., Murata R., Ishigaki T., Abe M. Comparison of radiosensitizing effect of KU-2285 and SR-2508 at low drug concentrations and doses. Int. J. Radiat. Oncol. Biol. Phys. 29:1994;587-590.
25. Pinkel D., Landegent J., Collins C., Fuscoe J., Segraves R., Lucas J., Gray J. Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4. Proc. Natl. Acad. Sci. U.S.A. 85:1988;9138-9142.
26. L.A. Marascuilo, R.C. Serlin, The two-sample Wilcoxon Test and the Mann-Whitney U-test, in: Statistical Methods for the Social and Behavioral Sciences, Freeman, New York, 1988, pp. 228-244.
27. Cornforth M.N., Goodwin E.H. The dose-dependent fragmentation of chromatin in human fibroblasts by 3.5 MeV a particles from 238 Pu: experimental and theoretical considerations pertaining to single-track effects. Radiat. Res. 127:1991;64-74.
28. Mariya Y., Streffer C., Fuhrmann C., Wojcik A. Correlation of radiation-induced micronucleus frequency with clonogenic survival in cells of one diploid and two tetraploid murine tumor cell lines of the same origin. Radiat. Res. 147:1997;29-34.
29. Bush C., McMillan T.J. Micronucleus formation in human tumour cells: lack of correlation with radiosensitivity. Br. J. Cancer. 67:1993;102-106.
30. Guo G.Z., Sasai K., Oya N., Takagi T., Shibuya K., Hiraoka M. Simultaneous evaluation of radiation-induced apoptosis and micronuclei in five cell lines. Int. J. Radiat. Biol. 73:1998;297-302.
31. Schwartz J.L. The radiosensitivity of the chromosomes of the cells of human squamous cell carcinoma cell lines. Radiat. Res. 129:1992;96-101.
32. Pekkola-Heino K., Joensuu H., Klemi P., Grenman R. Relation of DNA ploidy and proliferation rate to radiation sensitivity in squamous carcinoma cell lines. Arch. Otolaryngol. Head Neck Surg. 120:1994;750-754.
33. Sontag W., Knedlistchek G., Weibezahn K.F., Dertinger H. The DNA content of some mammalian cells measured by flow cytometry and its influence on radiation sensitivity. Int. J. Radiat. Biol. 57:1990;1183-1193.