Bicontinuous sucrose ester microemulsion: A new vehicle for topical delivery of niflumic acid

International Journal of Pharmaceutics

Volumn 176, Issue 1, 1998, Pages 39-45

  Bolzinger, M A ^a   Carduner, Thevenin C ^a   Poelman, M C ^a  

^a FACULTÉ DES SCIENCES PHARMACEUTIQUES ET BIOLOGIQUES   (France)

Author keywords

Bicontinuous structures; Methyl nicotinate; Microemulsions; Sucrose esters

Indexed keywords

DRUG VEHICLE; NICOTINIC ACID METHYL ESTER; NIFLUMIC ACID; SUCROSE ESTER DERIVATIVE;

ADULT; ANTIINFLAMMATORY ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; DOPPLER FLOWMETRY; DRUG FORMULATION; FEMALE; HUMAN; HUMAN EXPERIMENT; MICROEMULSION; NORMAL HUMAN; PRIORITY JOURNAL; SKIN BLOOD FLOW; TOPICAL DRUG ADMINISTRATION; VOLUNTEER;

EID: 0031758821     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(98)00292-0     Document Type: Article

References (26)

1. Ashton P., Walters K.A., Brain K.R., Hadgraft J. Surfactant effects in percutaneous absorption I. Effects on the transdermal flux of methyl nicotinate. Int. J. Pharm. 87:1992;261-264.
2. Ashton P., Walters K.A., Brain K.R., Hadgraft J. Surfactant effects in percutaneous absorption II. Effects on protein and lipid structure of the stratum corneum. Int. J. Pharm. 87:1992;265-269.
3. Bhargava H.N., Narurkar A., Lieb L.M. Using microemulsions for drug delivery. Pharm. Technol. 11(3):1987;46-54.
4. Brooks G.J. Advantages of sucrose esters in formulating cosmetic creams and lotions. Cosmet. Toiletries. 95:1980;73-76.
5. Carlfors J., Blute I., Schmidt V. Lidocaine in microemulsion-a dermal delivery system. J. Disper. Sci. Technol. 12(5 and 6):1991;467-482.
6. Constantinides P.P. Lipid microemulsions for improving drug dissolution and oral absorption. Pharm. Res. 12(11):1995;1561-1572.
7. Desai N.B., Lowicki N. New sucrose esters and their applications in cosmetics. Cosmet. Toiletries. 100:1985;55-58.
8. Desai N.B. Esters of sucrose and glucose as cosmetic materials. Cosmet. Toiletries. 105:1990;99-107.
9. Friberg S.E. Micelles, microemulsions, liquid crystals, and the structure of the stratum corneum lipids. J. Soc. Cosmet. Chem. 41:1990;155-171.
10. Guy R.H., Wester R.C., Tur E., Maibach H.I. Noninvasive assessments of the percutaneous absorption of methyl nicotinate in humans. J. Pharm. Sci. 72(9):1983;1077-1079.
11. Gasco M.R., Pattarino F., Lattanzi F. Long acting delivery systems for peptides: reduced plasma testosterone levels in male rats after a single injection. Int. J. Pharm. 62:1990;119-123.
12. Higuchi T. Physical chemical analysis of percutaneous absorption process from creams and ointments. J. Cosmet. Chem. 11:1960;85-97.
13. Jahn W., Strey R. Microstructure of microemulsions by freeze electron microscopy. J. Phys. Chem. 92:1988;2294-2301.
14. Kemken J., Ziegler A., Müller B.W. Influence of supersaturation on the pharmacodynamic effect of bupranolol after dermal administration using microemulsions as vehicle. Pharm. Res. 9(4):1992;554-558.
15. Mavon A., Zahouani H., Redoules D., Agache P., Gall Y., Humbert Ph. Sebum and stratum corneum lipids increase human skin surface free energy as determined from contact angle measurements: A study on two anatomical sites. Coll. Surf. B: Biointerfaces. 8:1997;147-155.
16. Meloni M., Poelman M.C., Lavazza M. LDV assessment of methyl nicotinate biological response in aqueous solution against that of a microemulsion system. Int. J. Cosmet. Sci. 16:1994;257-264.
17. Nobile L., Rovesti P., Svampa M.B. Study of the activity on the skin of sugar esters, sucroglycerides and derivatives when used as detergents and emulsifiers in cosmetics. Am. Perfum. Cosmet. 79:1964;19-28.
18. Ntawukuliyayo J.D., Bouckaert S., Remon J.P. Enhancement of dissolution of nifedipine using sucrose ester coprecipitates. Int. J. Pharm. 93:1993;209-214.
19. Poelman M.C., Piot B., Guyon F., De Roni M., Levêque J.L. Assessment of topical non-steroidal anti-inflammatory drugs. J. Pharm. Pharmacol. 41:1989;720-722.
20. Poelman M.C., Piot B., Mossino D. Evaluation by laser Doppler velocimetry of the anti-inflammatory activity of a topical niflumic acid ointment. S.T.P. Pharma. 1(1):1991;94-96.
21. Rieger M. Surfactant interactions with skin. Cosmet. Toiletries. 110:1995;31-50.
22. Schubert K.V., Kaler E.W. Nonionic microemulsions. Ber. Bunsen-Ges. Phys. Chem. 100(3):1996;190-205.
23. Thevenin M.A., Grossiord J.L., Poelman M.C. Sucrose esters/cosurfactant microemulsion systems for transdermal delivery: assessment of bicontinuous structures. Int. J. Pharm. 137:1996;177-186.
24. Treffel P., Gabard B. Feasibility of measuring the bioavailability of topical ibuprofen in commercial formulations using drug content in epidermis and a methyl nicotinate skin inflammation assay. Skin Pharmacol. 6:1993;268-275.
25. Walters K.A., Florence A.T., Dugard P.H. Interaction of polyoxyethylene alkyl ethers with cholesterol monolayers. J. Coll. Interface Sci. 89:1982;584-587.
26. Wilkin J.K., Fortner G., Reinhardt B.S.L.A., Vogt-Flowers O., Kilpatrick S.J., Carson Streeter W. Prostaglandins and nicotinate-provoked increase in cutaneous blood flow. Clin. Pharmacol. Ther. 38(3):1985;273-277.