Comparison of the safety and efficacy of the fixed combination of dorzolamide/timolol and the concomitant administration of dorzolamide and timolol: A clinical equivalence study

British Journal of Ophthalmology

Volumn 82, Issue 11, 1998, Pages 1249-1253

  Hutzelmann, Jill ^a   Owens, Susan ^a   Shedden, Arthur ^a   Adamsons, Ingrid ^a   Vargas, Enrique ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Instituto Nacional de Oftalmología "Dr Francisco Contreras Campos"   (Peru)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGLAUCOMA AGENT; DORZOLAMIDE; DORZOLAMIDE PLUS TIMOLOL; TIMOLOL; TIMOLOL MALEATE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG MIXTURE; DRUG SAFETY; EYE BURN; FEMALE; HUMAN; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OPEN ANGLE GLAUCOMA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TASTE DISORDER; TOPICAL DRUG ADMINISTRATION;

EID: 0031758746     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.82.11.1249     Document Type: Article

References (7)

1. Innovations in Ophthalmic Pharmaceuticals 1996-2005. Stanford, CA: Plan A, 1996:28-36.
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3. Strahlman E, Tipping R, Vogel R, et al and the Dorzolamide Additivity Study Group. The use of dorzolamide and pilocarpine as adjunctive therapy to timolol in patients with elevated intraocular pressure. Ophthalmology 1996;103: 1283-93.
4. Laibovitz R, Strahlman E, Barber B, et al. Comparison of quality of life and patient preference of dorzolamide and pilocarpine as adjunctive therapy to timolol in the treatment of glaucoma. J Glaucoma 1995;4:306-13.
5. Laibovitz R, Boyle J, Snyder E, et al. Dorzolamide versus pilocarpine as adjunctive therapy to timolol: a comparison of patient preference and impact on daily life. Clin Ther 1996;18:821-32.
6. Strohmaier K, Snyder E, Adamsons I. The long term safety and efficacy of COSOPT, a fixed combination of dorzolamide and timolol. Invest Ophthalmol Vis Sci 1996;37:S1102.
7. Boyle J, Ghosh K, Gieser D, et al, and the Dorzolamide/ Timolol Study Group. A randomized trial comparing the dorzolamide/timolol combination given BID to monotherapy with timolol and doizolamide. Ophthalmology (in press).