Restricted usage of T-cell receptor Vα-Vβ genes in infiltrating cells in the aortic tissue of a patient with atherosclerotic aortic aneurysm

International Angiology

Volumn 17, Issue 2, 1998, Pages 89-92

  Seko, Y ^a,b,c   Takahashi, N ^a   Sato, O ^a   Takagi, A ^a   Yagita, H ^b   Okumura, K ^b   Yazaki, Y ^c  

^a UNIVERSITY OF TOKYO   (Japan)

^b JUNTENDO UNIVERSITY   (Japan)

^c INSTITUTE FOR ADULT DISEASES   (Japan)

Author keywords

Aortic aneurysm; Atherosclerosis; Autoimmunity; Heat shock proteins; Receptors, antigens; T cell alpha beta genetics; T lymphocytes immunology

Indexed keywords

HEAT SHOCK PROTEIN 65; HLA ANTIGEN CLASS 1;

AGED; AORTA ANEURYSM; ARTICLE; ATHEROSCLEROSIS; AUTOIMMUNITY; CASE REPORT; CYTOTOXIC T LYMPHOCYTE; FEMALE; GENE EXPRESSION; HELPER CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPHOCYTIC INFILTRATION; MACROPHAGE; NATURAL KILLER CELL; RESTRICTION MAPPING; T LYMPHOCYTE; T LYMPHOCYTE RECEPTOR GENE;

AGED; AGED, 80 AND OVER; AORTIC ANEURYSM, THORACIC; ARTERIOSCLEROSIS; BACTERIAL PROTEINS; CHAPERONINS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MACROPHAGES; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTES;

EID: 0031758038     PISSN: 03929590     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Jonasson L, Holm J, Skalli O, Bondjers G, Hansson KG. Regional accumulation of T cells, macrophages, and smooth muscle cells in the human atherosclerotic plaque. Arteriosclerosis 1986;6:131-8.
2. Emeson EE, Robertson Jr AL. T lymphocytes in aortic and coronary intimas. Their potential role in atherogenesis. Am J Pathol 1988;130:369-76.
3. Hansson GK, Jonasson L, Seifcrt PS, Stemme S. Immune mechanisms in atherosclerosis. Arteriosclerosis 1989;9:567-78.
4. Seko Y, Minota S, Kawasaki A, Shinkai Y, Maeda K, Yagita H et al. Perforin-secreting killer cell infiltration and expression of a 65-kD heat-shock protein in aortic tissue of patients with Takayasu's arteritis. J Clin Invest 1994;93:750-8.
5. Seko Y, Sato O, Takagi A, Tada Y, Matsuo H, Yagita H et al. Restricted usage of T-cell receptor Vα-Vβ genes in infiltrating cells in aortic tissue of patients with Takayasu's arteritis. Circulation 1996;93:1788-90.
6. Seko Y, Ishiyama S, Nishikawa T, Kasajima T, Hiroe M, Kagawa N et al. Restricted usage of T-cell receptor Vα-Vβ genes in infiltrating cells in the hearts of patients with acute myocarditis and dilated cardiomyopathy. J Clin Invest 1995;96:1035-41.
7. + T cells respond to mycobacterial heat-shock protein. Nature 1989;340:309-12.
8. Born W, Hall L, Dallas A, Boymel J, Shinnick T, Young D et al. Recognition of a peptide antigen by heat shock-reactive γδ T lymphocytes. Science 1990;249:67-9.
9. Swanson SJ, Rosenzweig A, Seidman JG, Libby P. Diversity of T-cell antigen receptor Vβ gene utilization in advanced human atheroma. Arterioscler Thromb 1994;14:1210-4.