Incorporation of cortical bone allografts and autografts in rats. Expression patterns of mRNAs for the TGF-βs

Acta Orthopaedica Scandinavica

Volumn 69, Issue 5, 1998, Pages 537-544

  Virolainen, Petri ^a   Elima, Kati ^a   Metsäranta, Marjo ^a   Aro, Hannu T ^a   Vuorio, Eero ^a  

^a UNIVERSITY OF TURKU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; DECORIN; MESSENGER RNA; OSTEONECTIN; PROTEOGLYCAN; TETRACYCLINE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

ALLOGRAFT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOGRAFT; BONE GRAFT; CONTROLLED STUDY; CORTICAL BONE; GENE EXPRESSION; HEALING; HISTOLOGY; MESSENGER RNA SYNTHESIS; MICRORADIOGRAPHY; MICROSCOPY; NONHUMAN; OSSIFICATION; RAT;

EID: 0031757823     PISSN: 00016470     EISSN: None     Source Type: Journal    
DOI: 10.3109/17453679808997794     Document Type: Article

References (29)

1. Bianco P, Fisher L W, Young M F, Termine J D, Gehron R P. Expression and localization of the two small proteoglycans higlycan and decorin in developing human skeletal and non-skeletal tissues. J Histochem Cytochem 1990; 38: 1549-63.
2. Border W A, Noble N A. Transforming growth factor b in tissue fibrosis. N Eng J Med 1994; 10; 1286-92.
3. Burchardt H. The biology of bone graft repair. Clin Orthop 1983; 174: 28-42.
4. Centrella M, Horowitz M C, Wozney J M, McCarthy T L. Transforming growth factor-β gene family members and bone. Endoer Rev 1994; 15: 27-39.
5. Derynck R, Jarrett J A, Chen E Y, Goaddel D V. The murine transforming growth factor-β precursor. J Biol Chem 1986; 261: 4377-9.
6. Enneking W F, Mindell E R. Observations on massive retrieved human allogralts. J Bone Joint Surg (Am) 1991; 73:1123-42.
7. Enneking W F, Burchardt H, Puhl J J, Piotrowski G. Physical and biological aspects of repair in dog cortical-bone transplants. J Bone Joint Surg (Am) 1975; 57: 237-52.
8. Fedarko N S, Termine J D, Young M F, Gehron R B. Temporal regulation of hyaluronan and proteoglycan metabolism by human bone cells in vitro. J Biol Chem 1990; 265: 12200-9.
9. Friedlaender G E. Bone allografts: the biological consequences of immunological events. J Bone Joint Surg (Am) 1991; 73: 1119-22.
10. Gatherer D, Ten Dijke P, Baird D T, Akhurst R J. Expression of TGF-β isoforms during first trimester human embryogenesis. Development 1990; 110:445-60.
11. Hardingham T E, Fosang A J. Proteoglycans: many forms and functions. FASEB J 1992; 6: 861-70.
12. Joyce M E, Jingushi S, Bolander M E, Transforming growth factor-β in the regulation of fracture repair. Orthop Clin North Am 1990; 21: 199-209.
13. Kulkarni A B, Huh C-G, Becker D, et al. Transforming growth factor ß1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci USA 1993; 90: 770-4.
14. Kähäri V-M, Larjava H, Uitto J. Differential regulation of extracellular matrix proteoglycan (PG) gene expression: Transforming growth factor-β1 upregulates biglycan (PGI), and versican (large fibroblast PG) but down-regulates decorin (PGII) mRNA levels in human fibroblasts in culture. J Biol Chem 1991; 266; 10608-15.
15. Lind M, Schumacher B, Søballe K, Keller J, Melsen F, Bunger C. Transforming growth factor-ß enhances fracture healing in rabbit tibiae. Acta Orthop Scand 1993; 64: 553-6.
16. Markel M D, Wikenheiser M A, Chao E Y S. A study of fracture callus material properties: Relationship to the torsional strength of bone. J Orthop Res 1990; 8: 843-50.
17. Miller D A, Lee A, Matsui Y, Chen E Y, Moses H L, Derrynck R. Complementary DNA cloning of the murine transforming growth factor ß3 (TGF-ß3) precursor and the competitive expression of TGF-ß3 and TGF-ß1 messenger RNA in murine embryos and adult tissue. Mol Endocrinol 1989a; 3: 1926-34.
18. Miller D A, Lee A, Pelton R W, Chen E Y, Moses H L, Derrynck R. Murine transforming growth factor-ß2 cDNA sequence and expression in adult tissues and embryos. Mol Endocrinol 1989b; 3: 1108-14.
19. Pelker R R, Friedlaender G E, Markham T C. Effects of freezing and freeze-drying on the biomechanical properties of rat bone. J Orthop Res 1984; 1: 405-11.
20. Reddi A H. Regulation of cartilage and bone differentation by bone morphogenetic proteins. Curr Opin Cell Biol 1992; 4: 850-5.
21. Robey P G, Young M F, Flanders K C, et al. Osteoblasts synthesize and respond to transforming growth factor-type beta in vitro. J Cell Biol 1987; 105: 457-63.
22. Rosen V, Thies R S. The BMP proteins in bone formation and repair. Trends Genet 1992; 8: 97-102.
23. Sambrook J, Fritsch E F, Maniatis T. Molecular cloning, a laboratory manual, 2nd edn. Cold Spring Harbor Laboratory, Cold Spring Harbor 1989.
24. Schmid P, Cox D, Bilbe G, Maier R, McMaster G K. Differental expression of TGF-ß1, -ß2 and -ß3 genes during mouse embryogenesis. Development 1991; 111: 117-30.
25. Scott J E. Proteoglycan-fibrillar collagen interactions. Biochem J 1988; 252: 313-23.
26. Seyedin S M, Thomas T C, Thompson A, Rosen D M, Piez K A. Purification and characterization of two cartilage-inducing factors from bovine demineralized bone. Proc Natl Acad Sci USA 1985; 82: 2267-71.
27. Shull M M, Ormsby I, Kier A B, et al. Targeted distribution of the mouse transforming growth factor ß1 gene results in multifocal inflammatory disease. Nature 1992; 359: 693-9.
28. Virolainen P, Vuorio E, Aro H T. Gene expression at graft-host interfaces of cortical bone allografts and autografts. Clin Orthop 1993; 297: 144-9.
29. Virolainen P, Vuorio E, Aro H T. Expression of matrix genes during incorporation of cancellous bone allografts and autografts. Clin Orthop 1995; 317: 263-72.