A new BRCA1 mutation in a Filipino woman with a family history of breast and ovarian cancer

Diagnostic Molecular Pathology

Volumn 7, Issue 3, 1998, Pages 164-167

  Worsham, Maria J ^a   Nathanson, S David ^a   Pals, Gerard ^a   Christopherson, Pat ^a   Strunk, Mark ^a   Wolman, Sandra R ^a  

^a HENRY FORD HOSPITAL   (United States)

Author keywords

Breast and ovarian cancer; Filipino; New mutation; Protein truncation test; Stop codon

Indexed keywords

COMPLEMENTARY DNA; DNA; RNA;

ADULT; ARTICLE; ASIAN; BREAST CANCER; CASE REPORT; CONTROLLED STUDY; ETHNIC GROUP; FAMILY HISTORY; FEMALE; GENE MUTATION; GYNECOLOGIC CANCER; HUMAN; OVARY CANCER; PEDIGREE ANALYSIS; POINT MUTATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCREENING TEST; STOP CODON;

ADULT; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; DNA PRIMERS; DNA, NEOPLASM; FEMALE; FIBROADENOMA; GENES, BRCA1; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MICHIGAN; OVARIAN NEOPLASMS; PEDIGREE; PHILIPPINES; POINT MUTATION; RNA, NEOPLASM;

EID: 0031757119     PISSN: 10529551     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019606-199806000-00007     Document Type: Article

References (4)

1. Miki Y, Swensen J, Shattuck-Eidens D, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994;266:66-71.
2. Wooster R, Bignell F, Shattuck-Eidens D, et al. Identification of the breast cancer susceptibility gene BRCA2. Nature 1995;378:789-92.
3. Easton DF, Bishop DT, et al. Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. Am J Hum Genet 1993;52:678-701.
4. Easton DF, Ford D, et al. Breast and ovarian cancer incidence in BRCA1 mutation carriers. Am J Hum Genet 1995;56:265-71.