Monoclonal antibody 138H11 against gamma-glutamyltransferase provides a possible tool for targeting calicheamicin Θ to renal cell carcinomas

Advances in Experimental Medicine and Biology

Volumn 451, Issue , 1998, Pages 431-436

  Schmidt, C S ^a   Wrasidlo, W ^a   Kaufmann, O ^a   Scherberich, J E ^b   Gaedicke, G ^a   Fischer, P ^a,c  

^a HUMBOLDT UNIVERSITY   (Germany)

^b KH München Harlaching ^*

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALICHEAMICIN; GAMMA GLUTAMYLTRANSFERASE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 138H11; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER SURVIVAL; EPITHELIUM CELL; GENE TARGETING; HISTOPATHOLOGY; IMMUNOMODULATION; KIDNEY CARCINOMA; KIDNEY PROXIMAL TUBULE; NEPHRECTOMY; NONHUMAN; PRIORITY JOURNAL; SURVIVAL RATE;

EID: 0031756581     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-5357-1_66     Document Type: Article

References (10)

1. Goey SH, Verweij J, Stoter G., 1996: Immunotherapy of metastatic renal cell cancer. Ann.Onc. 7, 887-900
2. Fischer P, Störkel S, Haase W, Scherberich JE., 1991: Differential diagnosis of histogenetically distinct human epithelial renal tumours with a monoclonal antibody against gamma-glutamyltransferase. Cancer Immunol Immunother 33, 382-8
3. Fischer P, Scherberich JE, Schoeppe W., 1990: Comparative biochemical and immunological studies on gamma-glutamyltransferases from human kidney and renal cell carcinoma applying monoclonal antibodies. Clin Chim Acta 191, 185-200
4. Thoenes W, Störkel S, Rumpelt HJ., 1986: Histopathology and classification of renal cell tumors (adenomas, oncocytomas and carcinomas). The basic cytological and histopathological elements and their use for diagnostics. Pathol Res Pract 181, 125-43
5. Kaufmann O, Dietel M, Scherberich JE, Gaedicke G, Fischer P., 1997: Immunohistochemical differentiation of metastases of renal carcinomas versus other carcinomas with anti-GGT monoclonal antibody 138H11. Histopathology 31, 31-37
6. Fischer P, Baum RP, Tauber M, Boeckmann W, Weier S, Scherberich JE., 1992: Immunoscintigraphic localization of renal tumours in an extracorporeal perfusion model with a monoclonal antibody against gamma-glutamyltransferase. Cancer Immunol Immunother 35, 283-8
7. Reisfeld R, Mueller B, Schrappe M, Wargalla U, Yang H, Wrasidlo W., 1991: Antibody-drug conjugates for cancer therapy. Immunol Allergy Clin N Amer 11, 341-58
8. Nicolaou KC, Dai WM, Tsay SC, Estevez VA, Wrasidlo W. 1992: Designed enediynes: a new class of DNA-cleaving molecules with potent and selective anticancer activity. Science 256, 1172-8
9. Nicolaou KC, Li T, Nakada M, Hummel C, Hiatt A, Wrasidlo W. 1994: Calicheamicin θ: A rationally designed caliceamicin with extremely potent and selective DNA cleaving properties and apoptosis inducing activity. Angew Chem Int Ed 106, 183-186
10. Chapman AE, Goldstein LJ., 1995: Multiple drug resistance: Biologic basis and clinical significance in renal-cell carcinoma. Semin Oncol 22, 17-28