Essential fatty acid status in cell membranes and plasma of patients with primary Sjogren's syndrome. Correlations to clinical and immunologic variables using a new model for classification and assessment of disease manifestations

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 59, Issue 4, 1998, Pages 239-245

  Oxholm, P ^a   Asmussen, K ^b   Wiik, A ^c   Horrobin, D F ^d  

^a GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c STATENS SERUM INSTITUT   (Denmark)

^d Efamol Limited   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENIC ACID; ARACHIDONIC ACID DERIVATIVE; CHOLESTEROL ESTER; DIHOMO GAMMA LINOLENIC ACID; DOCOSAHEXAENOIC ACID; ESSENTIAL FATTY ACID; ICOSAPENTAENOIC ACID; LINOLEIC ACID; LINOLENIC ACID; MEMBRANE LIPID; PHOSPHOLIPID; RHEUMATOID FACTOR; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE CLASSIFICATION; ERYTHROCYTE LEVEL; FATTY ACID BLOOD LEVEL; FATTY ACID METABOLISM; FEMALE; HUMAN; HUMAN CELL; IMMUNOPATHOLOGY; MALE; PHOSPHOLIPID BLOOD LEVEL; PRIORITY JOURNAL; SJOEGREN SYNDROME; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 0031755413     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-3278(98)90136-3     Document Type: Article

References (19)

1. Price E. J., Venables P. J. W. The etiopathogenesis of Sjögren's syndrome. Sem Arthritis Rheum 1995; 25: 117-133.
2. Horrobin D. F. Essential fatty acid metabolism in diseases of connective tissue with special reference to scleroderma and to Sjögren's syndrome. Med Hypotheses 1984; 14: 233-247.
3. Oxholm P., Pedersen B. K. Horrobin D. F. Natural killer cell functions are related to the cell membrane composition of essential fatty acids: differences in healthy persons and patients with primary Sjögren's syndrome. Clin Exp Rheumatol 1992; 10: 229-234.
4. Oxholm P., Manthorpe R., Prause J. U. Horrobin D. F. Patients with primary Sjögren's syndrome treated for two months with evening primrose oil. Scand J Rheumatol 1986; 15: 103-108.
5. Swanson C. A., Levy J. A., Morrow W. J. W. Effect of low dietary lipid on the development of Sjögren's syndrome and haematological abnormalities in (NZBxNZW) F1 mice. Ann Rheum Dis 1989; 48: 765-770.
6. Oxholm P., Asmussen K. Primary Sjögren's syndrome: the challenge for classification of disease manifestations. J Intern Med 1996; 239: 467-474.
7. Asmussen K., Andersen V., Bendixen G., Bendtzen K., Prause J. U., Thorn J., Wiik A., Oxholm P. Quantitative assessment of clinical disease status in primary Sjögren's syndrome - a cross-sectional study using a new classification model. Scand J Rheumatol 1997; 26: 197-205.
8. Vitali C., Bombardieri S., Moutsopoulos H. et al. Preliminary criteria for the classification of Sjögren's syndrome. Results of a prospective concerted action supported by the European Community. Arthritis Rheum 1993; 36: 340-347.
9. Manthorpe R., Oxholm P., Prause J. U., Schiødt M. The Copenhagen criteria for Sjögren's syndrome. Scand J Rheumatol 1986; 61 (suppl.): 19-21.
10. Manku M. S., Horrobin D. F., Huang Y.-S., Morse N. Fatty acids in plasma and red cell membranes in normal humans. Lipids 1983; 18: 906-908.
11. Omega-6 Essential Fatty Acids. Pathophysiology and Roles in Clinical Medicine. Horrobin D. F., ed. New York: Wiley-Liss, 1990.
12. Zurier R. B. Fatty acids, inflammation and immune responses. Prostaglandins Leukot Essent Fatty Acids 1993; 48: 57-62.
13. Rothman D., DeLuca P., Zurier R. B. Botanical lipids: effects on inflammation, immune responses, and rheumatoid arthritis. Sem Arthritis Rheum 1995; 25: 87-96.
14. Tishler M., Yaron I., Raz A., Meyer F. A., Yaron M. Salivary eicosanoid concentration in patients with Sjögren's syndrome. Ann Rheum Dis 1996; 55: 202-204.
15. Oxholm P., Manthorpe R., Prause J. U., Horrobin D. J. Ratio between arachidonic acid and dihomogammalinolenic acid: a disease marker in primary Sjögren's syndrome. In: Homma S., Sugai S., Tojo T., Miyasaka N., Akizuki M., eds. Sjögren's Syndrome - State of the Art, Proceedings of the Fourth International Symposium. Amsterdam, New York: Kugler, 1994: 335-337.
16. Oxholm P., Horrobin D. F., Manthorpe R, Petersen J. Immmunoglobin production and eicosanoid precursors in patients with primary Sjögren's syndrome. Clin Exp Rheumatol 1995; 13: 128-129.
17. Asmussen K, Bendixen G., Schiødt M., Oxholm P. A new model for classification of disease manifestations in primary Sjögren's syndrome. Evaluation in a retrospective long-term study. J Intern Med 1996; 239: 475-482.
18. Oxholm P., Asmussen K. Standardized assessment of disease status in patients with primary Sjögren's syndrome. Criteria for disease activity and damage. Med Hypotheses 1998; 50: 483-492.
19. Rhodus N. L. Qualitative nutritional intake analysis of older adults with Sjögren's syndrome. Gerontol 1988; 7: 61-69.