Splice donor site mutations in the 3-hydroxy-3methylglutaryl coenzyme A reductase gene cause a deficiency of the endoplasmic reticulum 3-hydroxy-3- methylglutaryl coenzyme A reductase protein in UT2 cells

Journal of Lipid Research

Volumn 39, Issue 11, 1998, Pages 2182-2191

  Engfelt, William Harrison ^a   Masuda, Kimberly R ^a   Paton, Vincent G ^a   Krisans, Skaidrite K ^a  

^a SAN DIEGO STATE UNIVERSITY   (United States)

Author keywords

90 kDa peroxisomal reductase; Chinese hamster ovary cells; Cholesterol; Endoplasmic reticulum; Peroxisomes

Indexed keywords

COMPACTIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; MEVALONIC ACID;

ALLELE; ANIMAL CELL; ARTICLE; CHINESE HAMSTER; CHO CELL; CHOLESTEROL SYNTHESIS; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME DEFICIENCY; EXON; FEMALE; GENE INSERTION SEQUENCE; GENE MUTATION; INTRON; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLICEOSOME; STOP CODON;

ALLELES; ANIMALS; BLOTTING, NORTHERN; BLOTTING, SOUTHERN; CHO CELLS; CRICETINAE; DNA, COMPLEMENTARY; ENDOPLASMIC RETICULUM; EXONS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; MOLECULAR WEIGHT; MUTATION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RNA SPLICING; SEQUENCE ANALYSIS, DNA;

EID: 0031755082     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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