Growth hormone treatment prevents the decrease in insulin-like growth factor I gene expression in patients undergoing abdominal surgery

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 5, 1998, Pages 1566-1572

  Bjarnason, Ragnar ^a,b,c,e   Wickelgren, Ruth ^a   Hermansson, Majlis ^a   Hammarqvist, Folke ^d   Carlsson, Björn ^a   Carlsson, Lena M S ^a  

^a Res Ctr for Endocrinol and Metab

^b Intl Pediat Growth Research Center

^c UNIVERSITY OF GOTHENBURG   (Sweden)

^d KAROLINSKA INSTITUTE   (Sweden)

^e SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHILIN; GLUTAMINE; GROWTH HORMONE BINDING PROTEIN; HUMAN GROWTH HORMONE; INTRALIPID; SOMATOMEDIN; SOMATOMEDIN BINDING PROTEIN 2;

ABDOMINAL SURGERY; ADULT; AGED; ARTICLE; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GENE EXPRESSION; HORMONE RESISTANCE; HUMAN; MALE; MUSCLE ATROPHY; MUSCLE BIOPSY; MUSCLE MASS; PRIORITY JOURNAL; PROTEIN DEGRADATION; QUADRICEPS FEMORIS MUSCLE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUBCUTANEOUS DRUG ADMINISTRATION; TOTAL PARENTERAL NUTRITION;

ABDOMEN; AGED; AGED, 80 AND OVER; BIOPSY; CARRIER PROTEINS; FEMALE; GENE EXPRESSION; GLUTAMINE; HUMAN GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; MALE; MIDDLE AGED; MUSCLE, SKELETAL; PARENTERAL NUTRITION, TOTAL; POLYMERASE CHAIN REACTION; RECEPTORS, SOMATOTROPIN; RNA, MESSENGER; RNA-DIRECTED DNA POLYMERASE;

EID: 0031755033     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.83.5.1566     Document Type: Article

References (18)

1. Isaksson OPG, Jansson J-O, Gause IAM. 1982 Growth hormone stimulates longitudinal bone growth directly. Science. 216:1237-1239.
2. Isgaard J, Nilsson A, Lindahl A, Jansson J-O, Isaksson OGP. 1986 Effects of local administration of GH and IGF-1 on longitudinal bone growth in rats. Am J Physicol. 250:E367-E372.
3. Ross RJ, Chew SL. 1995 Acquired growth hormone resistance. Eur J Endocrinol. 132:655-660.
4. Hammarqvist F, Strömberg C, von der Decken A, Vinnars E, Wernerman J. 1992 Biosynthetic human growth hormone preserves both muscle protein synthesis, the decrease in muscle free glutamine and improves whole body nitrogen economy postoperatively. Ann Surg. 216:184-191.
5. Hermansson M, Wickelgren RB, Hammarqvist F, et al. 1997 Measurement of human growth hormone receptor mRNA by a quantitative polymerase chain reaction based assay: demonstration of reduced expression after elective surgery. J Clin Endocrinol Metab. 82:421-428.
6. Chomczynski P, Sacchi N. 1987 Single step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem. 162:156-159.
7. Steenbergh PH, Koonen-Reemst AM, Cleutjens CB, Sussenbach JS. 1991 Complete nucleotide sequence of the high molecular weight human IGF-I mRNA. Biochem Biophys Res Commun. 175:507-514.
8. Perrin S, Gilliland G. 1990 Site-specific mutagenesis using asymmetric polymerase chain reaction and a single mutant primer. Nucleic Acids Res. 18:7433-7438.
9. Haendler B, Hofer-Warbinek R, Hofer E. 1987 Complementary DNA for human T-cell cyclophilin. EMBO J. 6:947-950.
10. Carlsson LMS, Rowland AM, Clark RG, Gesundheit N, Wong WL. 1991 Ligand-mediated immunofunctional assay for quantitation of growth hormone-binding protein in human blood. J Clin Endocrinol Metab. 73:1216-1223.
11. Rodbard D, Munson J, De Jaen A. 1978 Radioimmunoassay and related procedures in medicine. Vienna: International Atomic Energy Agency; vol 1:469.
12. Manson JM, Wilmore DW. 1986 Positive nitrogen balance with human growth hormone and hypocaloric intravenous feeding. Surgery. 100:188-197.
13. Ward HC, Halliday D, Sim AJW. 1987 Protein and energy metabolism with biosynthetic human growth hormone after gastrointestinal surgery. Ann Surg. 206:56-61.
14. Hammarqvist F, Wernerman J, Ali MR, von der Decken A, Vinnars E. 1989 Addition of glutamine to total parenteral nutrition after elective abdominal surgery spares free glutamine in muscle, counteracts the fall in muscle protein synthesis and improves nitrogen balance. Ann Surg. 209:455-461.
15. Hoffman DM, O'Sullivan AJ, Baxter RC, Ho KK. 1994 Diagnosis of growthhormone deficiency in adults. Lancet. 344:1064-1068.
16. Rosén T, Bosaeus I, Tölli J, Lindstedt G, Bengtsson B-Å. 1993 Increased body fat mass and decreased extracellular fluid volume in adults with growth hormone deficiency. Clin Endocrinol (Oxf). 38:63-71.
17. Bjarnason R, Albertsson-Wikland K, Carlsson LMS. 1995 Acute and chronic effects of subcutaneous growth hormone (GH) injections on plasma levels of GH binding in short children. J Clin Endocrinol Metab. 80:2756-2760.
18. Johannsson G, Bjarnason R, Bramnert M, Carlsson LMS, Degerblad M, Manhem P. 1996 The individual responsiveness to growth hormone (GH) treatment in GH-deficient adults is dependent on the level of GH-binding protein, body mass index, age and gender. J Clin Endocrinol Metab. 81:1575-1581.