Society for Pediatric Research Presidential Address 1998: The SPR and 1- 800-NO-CLOTS: A common vision

Pediatric Research

Volumn 44, Issue 6, 1998, Pages 964-973

  Andrew, Maureen ^a,b,c  

^a MCMASTER UNIVERSITY   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c HAMILTON HEALTH SCIENCES   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHILD HEALTH CARE; CONFERENCE PAPER; MEDICAL EDUCATION; MEDICAL RESEARCH; MEDICAL SOCIETY; PEDIATRICS; PRIORITY JOURNAL;

EID: 0031754676     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-199812000-00024     Document Type: Conference Paper

References (43)

1. Pearson HA 1988 The Centennial History of the American Pediatric Society: 1888-1988. Yale University, New Haven
2. Goldstein JL, Brown MS 1997 The clinical investigators: bewitched, bothered, and bewildered. . . . but still beloved. J Clin Invest 99:2803-2812
3. Townsend CW 1894 The haemorrhagic disease of the newborn. Arch Pediatr 11:559-562
4. Dam CPH 1929 Cholesterinstoffwechsel in Huhnereierin und Huhnchen. Biochem Z 215:475-492
5. Mammen EF, Thomas WR, Seegers WH 1960 Thromb Diath Haemorrh 5:218-249
6. Walker FJ 1980 Regulation of activated protein C by a new protein: a possible function for bovine protein S. J Biol Chem 255:5521-5524
7. Esmon CT 1983 Protein C: biochemistry, physiology, and clinical implications. Blood 62:1155-1158
8. Yasuda F, Hayashi T, Tanitame K, Nishioka J, Suzuki K 1995 Molecular cloning and functional characterization of rat plasma protein S. J Biochem 117:374-383
9. Dreyfus M, Magny J, Bridey F, Schwarz H, Planche C, Dehan M, Tchernia G 1991 Treatment of homozygous protein C deficiency and neonatal purpura fulminans with a purified protein C concentrate. N Engl J Med 325:1565-1568
10. Auberger K 1992 Evaluation of a new protein C concentrate and comparison of protein C assays in a child with congenital protein C deficiency. Ann Hematol 64:146-151
11. Dreyfus M 1995 Replacement therapy with a monoclonal antibody purified protein C concentrate in newborns with severe congenital protein C deficiency. Semin Thromb Hemost 21:371-381
12. Muller F 1995 Purpura fulminans in severe congenital protein C deficiency: monitoring of treatment with protein C concentrate. Eur J Pediatr 155:20-25
13. Monagle P, Andrew M, Halton J, Marlar R, Jardine L, Vegh P, Johnston M, Webber C, Massicotte MP 1998 Homozygous protein C deficiency: description of a new mutation and successful treatment with low molecular weight heparin. Thromb Haemost 79:756-761
14. Dahlback B, Hildebrand B 1994 Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V. Proc Natl Acad Sci USA 91:1396-1400
15. Poort SR, Rosendaal FR, Reitsma PH, Bertina RM 1996 A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 88:3698-3703
16. Nowak-Gottl U, von Kries R, Gobel U 1997 Neonatal symptomatic thromboembolism in Germany: two year survey. Arch Dis Child 76:F163-F167
17. Mills SL, Jackson DC, Older RA 1980 The incidence and etiologies and avoidance of complications of pulmonary angiography in a large series. Diag Radiol 136:295-299
18. Bick RL, Pegram M 1994 Syndromes of hypercoagulability and thrombosis: a review. Semin Thromb Haemost 20:109-132
19. Lane DA, Mannucci PM, Bauer KA 1996 Inherited thrombophilia: part 1. Thromb Haemost 76:651-662
20. Lane DA, Mannucci PM, Bauer KA, Bertina RM, Bochkov NP, Boulyjenkov V, Chandy M, Dahlback B, Ginter EK, Miletich JP, Rosendaal FR, Seligsohn U 1997 Inherited thrombophilia: part 2. Thromb Haemost 76:824-834
21. deVeber G, Adams M, Andrew M, Canadian Pediatric Neurologists 1995 Canadian pediatric ischemic stroke registry (analysis III). Can J Neurol Sci 22:S24-S26
22. Andrew M, Paes B, Milner R, Johnston M, Mitchell L, Tollefsen D, Powers P 1987 Development of the human coagulation system in the full-term infant. Blood 70:165-172
23. Andrew M, Paes B, Milner R, Johnston M, Mitchell L, Tollefsen D, Castle V, Powers P 1988 Development of the human coagulation system in the healthy premature infant. Blood 72:1651-1657
24. Andrew M, Vegh P, Johnston M, Bowker J, Ofosu F, Mitchell L 1992 Maturation of the hemostatic system during childhood. Blood 80:1998-2005
25. Reverdiau-Moalic P, Delahousse B, Bardos GBP, Leroy J, Gruel Y 1996 Evolution of blood coagulation activators and inhibitors in the healthy human fetus. Blood 88:900-906
26. Andrew M, Schmidt B, Mitchell L, Paes B, Ofosu F 1990 Thrombin generation in newborn plasma is critically dependent on the concentration of prothrombin. Thromb Haemost 63:27-30
27. Vieira A, Ofosu F, Andrew M 1991 Heparin sensitivity and resistance in the neonate: an explanation. Thromb Res 63:85-99
28. Dautzenberg M, Fischer A, Regli V, Bouygues P 1989 Bleeding times in children and neonates using a new standardized simplate device. Thromb Haemost 62:287(abstr)
29. Nitschmann E, Monagel P, Andrew M 1998 Morphological and biochemical features affecting the anti-thrombotic properties of the aorta of adult rabbits and rabbit pups. Pediatr Res 43:1-6
30. Xu L, Delorme M, Berry L, Brooker L, Mitchell L, Andrew M 1991 Thrombin generation in newborn and adult plasma in the presence of an endothelial surface. Thromb Haemost 65:1230(abstr)
31. Xu L, Delorme M, Berry L, Ofosu F, Mitchell L, Paes B, Andrew M 1995 Alpha-2-macroglobulin remains as important as ATIII for thrombin regulation in cord plasma in the presence of endothelial cell surfaces. Pediatr Res 37:1-6
32. Mitchell L, Piovella F, Ofosu F, Andrew M 1991 Alpha-2-macroglobulin may provide protection from thromboembolic events in antithrombin III deficient children. Blood 78:2299-2304
33. Andrew M, Marzinotto V, Brooker L, Adams M, Ginsberg J, Freedom R, Williams W 1994 Oral anticoagulant therapy in pediatric patients: a prospective study. Thromb Haemost 71:265-269
34. Andrew M, Mitchell L, Vegh P, Ofosu F 1994 Thrombin regulation in children differs from adults in the absence and presence of heparin. Thromb Haemost 72:836-842
35. Andrew M, Ofosu F, Schmidt B, Brooker L, Hirsh J, Buchanan M 1988 Heparin clearance and ex vivo recovery in newborn piglets and adult pigs. Thromb Res 52:517-527
36. Andrew M, Ofosu F, Brooker L, Buchanan M 1989 The comparison of the pharmacokinetics of a low molecular heparin in the newborn and adult pig Thromb Res 56:529-539
37. Bernstein D, Coupey S, Schonberg S 1986 Pulmonary embolism in adolescents. Am J Dis Child 140:667-671
38. Carter C, Gent M 1982 The epidemiology of venous thrombosis. In: Colman R, Hirsh J, Marder V, Salzman E (eds) Hemostasis and Thrombosis: Basic Principles and Clinical Practice. JB Lippincott, Philadelphia, pp 805-819
39. David M, Andrew M 1993 Venous thromboembolism complications in children: a critical review of the literature. J Pediatr 123:337-346
40. Andrew M, David M, Adams M, Ali K, Anderson R, Barnard D, Berstein M, Brisson L, Cairney B, DeSai D, Grant R, Israels S, Jardine L, Luke B, Massicotte MP, Silva M 1994 Venous thromboembolic complications (VTE) in children: first analyses of the Canadian registry of VTE. Blood 83:1251-1257
41. Schmidt B, Andrew M 1994 A prospective international registry of neonatal thrombotic diseases. Pediatr Res 35:170(abstr)
42. Beruhe C, David M, Laxer R, Adams M, St-Cyr C, Vegh P, Andrew M 1998 The relationship between non-specific inhibitors in children with systemic lupus erythematosus and thromboembolic complications: a cross-sectional study. Pediatr Res 4:351-356
43. Lindblad B, Bergqvist D 1989 Aggressive or conservative treatment in subclavian vein thrombosis. In: Eklof B, Gjores J, Thulesius O, Bergqvist D (eds) Controversies in the Management of Venous Disorders. Butterworth & Co, London, pp 141-158